Objective To study the role of three-dimensional computed tomography and reconstruction (3 - DCT) in the operative treatment of developmental dysplasia of the hip. Methods Twenty cases of developmental dysplasia of hi...Objective To study the role of three-dimensional computed tomography and reconstruction (3 - DCT) in the operative treatment of developmental dysplasia of the hip. Methods Twenty cases of developmental dysplasia of hip were examined preoperatively with X-ray and 3 -DCT. The 3 - EXIT data were compared with the operative findings. Results In 9 out of 16 cases, X-ray and 3 - EXIT results were consistent with each other. For the remaining 7 cases, 3 - EXIT revealed deformities not shown on X-ray and the operative plans were modified according to the findings. Conclusion 3 - DCT provides a better image of hip dislocation and is helpful to decide the surgical approach and degree of correction. 5 refs.展开更多
Duchenne muscular dystrophy (DMD) is a fatal genetic disease for the youth and children. 8 biopsies of DMD patients were determined and demonstrated that the membrane_binding nitric oxide synthase was enriched in norm...Duchenne muscular dystrophy (DMD) is a fatal genetic disease for the youth and children. 8 biopsies of DMD patients were determined and demonstrated that the membrane_binding nitric oxide synthase was enriched in normal skeletal muscles and was little in DMD muscles. The results from Western blot and immunohistochemistry showed that inducible nitric oxide synthase (iNOS) was overexpressed in DMD muscle fibers, while a small amount of highly localized iNOS can be found in normal fibers. Based on these findings, it is proposed that the mechanism of progressive injury in DMD muscle might be associated with the abnormal expression of iNOS.展开更多
文摘Objective To study the role of three-dimensional computed tomography and reconstruction (3 - DCT) in the operative treatment of developmental dysplasia of the hip. Methods Twenty cases of developmental dysplasia of hip were examined preoperatively with X-ray and 3 -DCT. The 3 - EXIT data were compared with the operative findings. Results In 9 out of 16 cases, X-ray and 3 - EXIT results were consistent with each other. For the remaining 7 cases, 3 - EXIT revealed deformities not shown on X-ray and the operative plans were modified according to the findings. Conclusion 3 - DCT provides a better image of hip dislocation and is helpful to decide the surgical approach and degree of correction. 5 refs.
文摘Duchenne muscular dystrophy (DMD) is a fatal genetic disease for the youth and children. 8 biopsies of DMD patients were determined and demonstrated that the membrane_binding nitric oxide synthase was enriched in normal skeletal muscles and was little in DMD muscles. The results from Western blot and immunohistochemistry showed that inducible nitric oxide synthase (iNOS) was overexpressed in DMD muscle fibers, while a small amount of highly localized iNOS can be found in normal fibers. Based on these findings, it is proposed that the mechanism of progressive injury in DMD muscle might be associated with the abnormal expression of iNOS.
