The accumulation of undesirable deposits on the heat exchange surface represents a critical issue in industrial heat exchangers.Taking experimental measurements of the fouling is relatively difficult and,often,this me...The accumulation of undesirable deposits on the heat exchange surface represents a critical issue in industrial heat exchangers.Taking experimental measurements of the fouling is relatively difficult and,often,this method does not lead to precise results.To overcome these problems,in the present study,a new approach based on an Artificial Neural Network(ANN)is used to predict the fouling resistance as a function of specific measurable variables in the phosphoric acid concentration process.These include:the phosphoric acid inlet and outlet temperatures,the steam temperature,the phosphoric acid density,the phosphoric acid volume flow rate circulating in the loop.Some statistical accuracy indices are employed simultaneously to justify the interrelation between these independent variables and the fouling resistance and to select the best training algorithm allowing the determination of the optimal number of hidden neurons.In particular,the BFGS quasi-Newton back-propagation approach is found to be the most performing of the considered training algorithms.Furthermore,the best topology ANN for the shell and tube heat exchanger is obtained with a network consisting of one hidden layer with 13 neurons using a tangent sigmoid transfer function for the hidden and output layers.This model predicts the experimental values of the fouling resistance with AARD%=0.065,MSE=2.168×10^(−11),RMSE=4.656×10^(−6)and r^(2)=0.994.展开更多
AIM: To assess whether juvenile chronic ferric iron ingestion limit colitis and dysbiosis at adulthood in rats and mice. METHODS: Two sets of experiments were designed. In the first set, recently weaned mice were eith...AIM: To assess whether juvenile chronic ferric iron ingestion limit colitis and dysbiosis at adulthood in rats and mice. METHODS: Two sets of experiments were designed. In the first set, recently weaned mice were either orally administered ferrous (Fe2+) iron salt or ferric (Fe3+) microencapsulated iron for 6 wk. The last week of experiments trinitrobenzene sulfonic acid (TNBS) colitis was induced. In the second set, juvenile rats received the microencapsulated ferric iron for 6 wk and were also submitted to TNBS colitis during the last week of experiments. In both sets of experiments, animals were sacrificed 7 d after TNBS instillation. Severity of the inflammation was assessed by scoring macroscopic lesions and quantifying colonic myeloperoxidase (MPO) activity. Alteration of the microflora profile was estimated usingquantitative polymerase chain reaction (qPCR) by measuring the evolution of total caecal microflora, Bacteroidetes, Firmicutes and enterobacteria. RESULTS: Neither ferrous nor ferric iron daily exposures at the juvenile period result in any effect in control animals at adulthood although ferrous iron repeated administration in infancy limited weight gain. Ferrous iron was unable to limit the experimental colitis (1.71 ± 0.27 MPO U/mg proteinvs 2.47 ± 0.22 MPO U/mg protein in colitic mice). In contrast, ferric iron significantly prevented the increase of MPO activity (1.64 ± 0.14 MPO U/mg protein) in TNBS-induced colitis. Moreover, this positive effect was observed at both the doses of ferric iron used (75 and 150 mg/kg per day po - 6 wk). In the study we also compared, in both rats and mice, the consequences of chronic repeated low level exposure to ferric iron (75 mg/kg per day po - 6 wk) on TNBS-induced colitis and its related dysbiosis. We confirmed that ferric iron limited the TNBS-induced increase of MPO activity in both the rodent species. Furthermore, we assessed the ferric iron incidence on TNBS-induced intestinal microbiota dysbiosis. At first, we needed to optimize the isolation and quantify DNA copy numbers using standard curves to perform by qPCR this interspecies comparison. Using this approach, we determined that total microflora was similar in control rats and mice and was mainly composed of Firmicutes and Bacteroidetes at a ratio of 10/1. Ferric juvenile administration did not modify the microflora profile in control animals. Total microflora numbers remained unchanged whichever experimental conditions studied. Following TNBS-induced colitis, the Firmicutes/Bacteroidetes ratio was altered resulting in a decrease of the Firmicutes numbers and an increase of the Bacteroidetes numbers typical of a gut inflammatory reaction. In parallel, the subdominant population, the enterobacteria was also increased. However, ferric iron supplementation for the juvenile period prevented the increase of Bacteroidetes and of enterobacteria numbers consecutive to the colitis in both the studied species at adulthood.CONCLUSION: Rats and mice juvenile chronic ferric iron ingestion prevents colitis and dysbiosis at adulthood as assessed by the first interspecies comparison.展开更多
This paper illustrates approaches to flooding risk governance in a territory where a high density of population corresponds to a high level of industrial activities and a significant development of transport infrastru...This paper illustrates approaches to flooding risk governance in a territory where a high density of population corresponds to a high level of industrial activities and a significant development of transport infrastructures in a transboundary context between France, Germany and Switzerland. In the last few years, some fundamental changes in European official instructions about risks and especially about flooding risks occurred. Substantial public policy challenges remain in order to promote a broad-based resilient territory twinned with local knowledge of sustainable land management and civic participation in local governance. The survey is based on a GIS study and questionnaires with a representative panel of 235 stakeholders from the studied territory. Our statistical results demonstrate that, in spite of a deep-rooted mindset as regards flooding hazards, local population awareness of the territorial vulnerability is not related to important challenges. A hierarchical analysis of the data shows that the awareness of stakeholders is less related to the importance of risks when the territorial level decreases. It also highlights the decline of solidarity among neighbouring communities when the distance from the industrial axis increases. Greatly impacted by flooding risks, industrial activities of the regional basin are paradoxically not really perceived as common challenges. Such a case study illustrates how public policies need to be relevant to the adapted levels. Awareness of common issues is a central target to develop acceptance in order to provide an efficient framework of resilience, including willingness to pay to reduce the risk and solidarity in local development compensations.展开更多
The objective of this paper is to present a new method for designing absorbing or non-reflective boundary conditions (ABC) or (NRBC), illustrated by the case study of the modelling of a solid body in water, specifical...The objective of this paper is to present a new method for designing absorbing or non-reflective boundary conditions (ABC) or (NRBC), illustrated by the case study of the modelling of a solid body in water, specifically the capillary gravity waves generated by its motion at the surface. The study analyses the flow of an inviscid, barotropic, and compressible fluid around the stationary solid body. The dynamic behaviour of the fluid is analysed using a two-dimensional coupled Neumann-Kelvin model extended with capillarity and inertia terms. For computational purposes, it is necessary to truncate the unbounded spatial domain with artificial boundaries and then introduce appropriate absorbing boundary conditions. The propagation of short wavelength waves in a convective fluid medium with significant differences in properties between the interior and the surface of the fluid presents a number of difficulties in the design of these conditions. The results are illustrated numerically and commented upon.展开更多
Wireless sensors networks consist of a number of sensors nodes connected through a wireless network that collect data to be treated locally or relayed to the sink node using multi-hop wireless transmission. Several so...Wireless sensors networks consist of a number of sensors nodes connected through a wireless network that collect data to be treated locally or relayed to the sink node using multi-hop wireless transmission. Several solutions were proposed to minimize the amount of information flowing within the network. Clustering algorithms is one solution and mechanism that enables the creation of sensor’s clusters;each sensor is dominated by elected routers. In order to limit energy consumption, the clustering around the sensor is established: sensors linked to the router transmit relayed data thereafter outward. The number of messages sent and the transmission range are thus reduced. This article tackles this issue by unveiling proposed techniques in the same line of researches and proposing a clustering mechanism based on the amount of energy remaining in the sensors. The simulation results show that proposed method can achieve higher network lifetime by comparison to original LEACH.展开更多
文摘The accumulation of undesirable deposits on the heat exchange surface represents a critical issue in industrial heat exchangers.Taking experimental measurements of the fouling is relatively difficult and,often,this method does not lead to precise results.To overcome these problems,in the present study,a new approach based on an Artificial Neural Network(ANN)is used to predict the fouling resistance as a function of specific measurable variables in the phosphoric acid concentration process.These include:the phosphoric acid inlet and outlet temperatures,the steam temperature,the phosphoric acid density,the phosphoric acid volume flow rate circulating in the loop.Some statistical accuracy indices are employed simultaneously to justify the interrelation between these independent variables and the fouling resistance and to select the best training algorithm allowing the determination of the optimal number of hidden neurons.In particular,the BFGS quasi-Newton back-propagation approach is found to be the most performing of the considered training algorithms.Furthermore,the best topology ANN for the shell and tube heat exchanger is obtained with a network consisting of one hidden layer with 13 neurons using a tangent sigmoid transfer function for the hidden and output layers.This model predicts the experimental values of the fouling resistance with AARD%=0.065,MSE=2.168×10^(−11),RMSE=4.656×10^(−6)and r^(2)=0.994.
基金Supported by Institut Polytechnique LaSalle Beauvais
文摘AIM: To assess whether juvenile chronic ferric iron ingestion limit colitis and dysbiosis at adulthood in rats and mice. METHODS: Two sets of experiments were designed. In the first set, recently weaned mice were either orally administered ferrous (Fe2+) iron salt or ferric (Fe3+) microencapsulated iron for 6 wk. The last week of experiments trinitrobenzene sulfonic acid (TNBS) colitis was induced. In the second set, juvenile rats received the microencapsulated ferric iron for 6 wk and were also submitted to TNBS colitis during the last week of experiments. In both sets of experiments, animals were sacrificed 7 d after TNBS instillation. Severity of the inflammation was assessed by scoring macroscopic lesions and quantifying colonic myeloperoxidase (MPO) activity. Alteration of the microflora profile was estimated usingquantitative polymerase chain reaction (qPCR) by measuring the evolution of total caecal microflora, Bacteroidetes, Firmicutes and enterobacteria. RESULTS: Neither ferrous nor ferric iron daily exposures at the juvenile period result in any effect in control animals at adulthood although ferrous iron repeated administration in infancy limited weight gain. Ferrous iron was unable to limit the experimental colitis (1.71 ± 0.27 MPO U/mg proteinvs 2.47 ± 0.22 MPO U/mg protein in colitic mice). In contrast, ferric iron significantly prevented the increase of MPO activity (1.64 ± 0.14 MPO U/mg protein) in TNBS-induced colitis. Moreover, this positive effect was observed at both the doses of ferric iron used (75 and 150 mg/kg per day po - 6 wk). In the study we also compared, in both rats and mice, the consequences of chronic repeated low level exposure to ferric iron (75 mg/kg per day po - 6 wk) on TNBS-induced colitis and its related dysbiosis. We confirmed that ferric iron limited the TNBS-induced increase of MPO activity in both the rodent species. Furthermore, we assessed the ferric iron incidence on TNBS-induced intestinal microbiota dysbiosis. At first, we needed to optimize the isolation and quantify DNA copy numbers using standard curves to perform by qPCR this interspecies comparison. Using this approach, we determined that total microflora was similar in control rats and mice and was mainly composed of Firmicutes and Bacteroidetes at a ratio of 10/1. Ferric juvenile administration did not modify the microflora profile in control animals. Total microflora numbers remained unchanged whichever experimental conditions studied. Following TNBS-induced colitis, the Firmicutes/Bacteroidetes ratio was altered resulting in a decrease of the Firmicutes numbers and an increase of the Bacteroidetes numbers typical of a gut inflammatory reaction. In parallel, the subdominant population, the enterobacteria was also increased. However, ferric iron supplementation for the juvenile period prevented the increase of Bacteroidetes and of enterobacteria numbers consecutive to the colitis in both the studied species at adulthood.CONCLUSION: Rats and mice juvenile chronic ferric iron ingestion prevents colitis and dysbiosis at adulthood as assessed by the first interspecies comparison.
文摘This paper illustrates approaches to flooding risk governance in a territory where a high density of population corresponds to a high level of industrial activities and a significant development of transport infrastructures in a transboundary context between France, Germany and Switzerland. In the last few years, some fundamental changes in European official instructions about risks and especially about flooding risks occurred. Substantial public policy challenges remain in order to promote a broad-based resilient territory twinned with local knowledge of sustainable land management and civic participation in local governance. The survey is based on a GIS study and questionnaires with a representative panel of 235 stakeholders from the studied territory. Our statistical results demonstrate that, in spite of a deep-rooted mindset as regards flooding hazards, local population awareness of the territorial vulnerability is not related to important challenges. A hierarchical analysis of the data shows that the awareness of stakeholders is less related to the importance of risks when the territorial level decreases. It also highlights the decline of solidarity among neighbouring communities when the distance from the industrial axis increases. Greatly impacted by flooding risks, industrial activities of the regional basin are paradoxically not really perceived as common challenges. Such a case study illustrates how public policies need to be relevant to the adapted levels. Awareness of common issues is a central target to develop acceptance in order to provide an efficient framework of resilience, including willingness to pay to reduce the risk and solidarity in local development compensations.
文摘The objective of this paper is to present a new method for designing absorbing or non-reflective boundary conditions (ABC) or (NRBC), illustrated by the case study of the modelling of a solid body in water, specifically the capillary gravity waves generated by its motion at the surface. The study analyses the flow of an inviscid, barotropic, and compressible fluid around the stationary solid body. The dynamic behaviour of the fluid is analysed using a two-dimensional coupled Neumann-Kelvin model extended with capillarity and inertia terms. For computational purposes, it is necessary to truncate the unbounded spatial domain with artificial boundaries and then introduce appropriate absorbing boundary conditions. The propagation of short wavelength waves in a convective fluid medium with significant differences in properties between the interior and the surface of the fluid presents a number of difficulties in the design of these conditions. The results are illustrated numerically and commented upon.
文摘Wireless sensors networks consist of a number of sensors nodes connected through a wireless network that collect data to be treated locally or relayed to the sink node using multi-hop wireless transmission. Several solutions were proposed to minimize the amount of information flowing within the network. Clustering algorithms is one solution and mechanism that enables the creation of sensor’s clusters;each sensor is dominated by elected routers. In order to limit energy consumption, the clustering around the sensor is established: sensors linked to the router transmit relayed data thereafter outward. The number of messages sent and the transmission range are thus reduced. This article tackles this issue by unveiling proposed techniques in the same line of researches and proposing a clustering mechanism based on the amount of energy remaining in the sensors. The simulation results show that proposed method can achieve higher network lifetime by comparison to original LEACH.