期刊文献+
共找到2篇文章
< 1 >
每页显示 20 50 100
The combined effects of lysozyme and ascorbic acid on microstructure and properties of zein-based films 被引量:1
1
作者 Dongwei Wei Weizhi Huo +2 位作者 Guangmeng Li Qiuling Xie Yanbin Jiang 《Chinese Journal of Chemical Engineering》 SCIE EI CAS CSCD 2018年第3期648-656,共9页
Edible zein-based films containing lysozyme(LY) and ascorbic acid(AA) were developed in the presence of polyethylene glycol 400(PEG 400), the combined effects of LY and AA on the microstructure, mechanical properties ... Edible zein-based films containing lysozyme(LY) and ascorbic acid(AA) were developed in the presence of polyethylene glycol 400(PEG 400), the combined effects of LY and AA on the microstructure, mechanical properties and release properties of developed zein films were investigated in detail. The results of microstructure characterization indicated that zein-based films became compact and smooth, and LY aggregates were well distributed in the zein matrix because of the simultaneous addition of LY and AA. The results of mechanical tests showed that because of the synergistic effects of LY and AA on zein film, elongation at break of zein-based film could be up to 138%, which was 34.5 times higher than that of zein control film. LY release tests showed that when the concentration of AA was less than 3.1 mg·cm^(-2), the release rate of LY significantly decreased by 33.7%, and the total release increased by 80.6%. While the release profiles of AA showed that the release rate and total release of AA from the films containing LY increased by approximately 68.9% and 61.7% than the films without LY. Good antioxidant and sustained antimicrobial activities were found for the developed zein films. 展开更多
关键词 Antimicrobial Antioxidant Zein Bioactive packaging Lysozyme Ascorbic acid
下载PDF
Bio-inspired Cell Membrane Ingredient Cholesterol-conjugated Chitosan as a Potential Material for Bone Tissue Repair 被引量:1
2
作者 LI Zhenzhen WEN Jianhua +4 位作者 JIA Weijian DING Shan XIA Xiaohui ZHOU Changren HUANG Yadong 《Chemical Research in Chinese Universities》 SCIE CAS CSCD 2016年第3期406-413,共8页
We prepared a cholesterol-conjugated chitosan(CHCS) material and evaluated its potential application as a bone tissue repair material by in vitro cell experiments. Cell proliferation, differentiation and morphology ... We prepared a cholesterol-conjugated chitosan(CHCS) material and evaluated its potential application as a bone tissue repair material by in vitro cell experiments. Cell proliferation, differentiation and morphology on CHCS membrane surfaces with different graft degrees were assessed in mouse pre-osteoblasts MC3T3-E1 cells. The results indicate that CHCS materials could promote the proliferation of MC3T3-E1 cells at low graft degrees, but the CHCS material with high graft degree inhibits the proliferation of cells in contrast to the pure chitosan membrane. However, the alkaline phosphatase(ALP) activity of MC3T3-E1 ceils on different CHCS membrane surface increased with in- creasing graft degrees of cholesterol. The area of cells stretched onto the surface of CHCS materials was larger than on the surface of CS materials, and more microfilaments and stress fibers in cells were observed on CHCS materials than on the pure chitosan material surface. After 7 d, the expression of related osteogenic marker genes, such as rum-related transcription factor 2(Runx2), osterix(OSX), osteocalcin(OCN), osteopontin(OPN), ALP and collagen I(COL-I) were all up-regulated in CHCS materials to different degrees compared to pure chitosan material, which in- dicated that the CHCS materials facilitated MC3T3-EI cell differentiation and maturation, Characterizing CHCS materials is useful in designing and developing strategies for bone tissue engineering. 展开更多
关键词 Bone repair material CHITOSAN CHOLESTEROL MC3T3-E1 Cell differentiation
原文传递
上一页 1 下一页 到第
使用帮助 返回顶部