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Fingerprinting of the Acacia nilotica (L.) Bark Extract Having Antibacterial Property
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作者 Jayshree D. Patel Nirmal S. Sahay Vipin Kumar 《Journal of Health Science》 2015年第3期123-127,共5页
Acacia nilotica (L.) Delile, commonly known as "Babul", is reported for its medicinal property since ages. Plant is recognized for its medicinal use in traditional practices. For the study, phytochemicals were ext... Acacia nilotica (L.) Delile, commonly known as "Babul", is reported for its medicinal property since ages. Plant is recognized for its medicinal use in traditional practices. For the study, phytochemicals were extracted as well as identified from four different solvents and their antibacterial property was determined. The fingerprinting was accomplished using HPTLC and the MIC (Minimum Inhibitory Concentration) was elucidated using standard protocols. Two Gram positive (Staphylococcus aureus and Bacillus subtilis) and two Gram negative (Escherichia coli and Pseudomonas aeruginosa) bacteria were selected for the antibacterial screening. The major phytochemicals identified in the extract of the bark of A. nilotica were catechin/epicatechin, ellagic acid and m-digallic acid. Excellent antimicrobial activity was found in chloroform (40 ~tg/mL) and methanol (60 ~g/mL) extracts against Pseudomonas aeruginosa. The chloroform extracts consist of higher number of phytochemicals/bands as compared with other extracts and demonstrated significant antibacterial activity against all the test bacterial species. 展开更多
关键词 Acacia nilotica antimicrobial screening fingerprinting BACTERIA HPTLC
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Ethnomedicinal, phytochemical and pharmacological updates on Hygrophila auriculata (Schum.) Hiene: an overview
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作者 Neeraj K. Sethiya Nasir M. Ahmed +3 位作者 Raeesh M. Shekh Vivek Kumar Pawan Kumar Singh Vipin Kumar 《Journal of Integrative Medicine》 CAS CSCD 2018年第5期299-311,共13页
This article explores the most recent evidence-based information on ethnomedicinal, phytochemical and pharmacological understanding of Hygrophila auriculata for the treatment of various diseases and health conditions.... This article explores the most recent evidence-based information on ethnomedicinal, phytochemical and pharmacological understanding of Hygrophila auriculata for the treatment of various diseases and health conditions. Various ethnomedicinal writings suggest the use of the plant or its parts for the treatment of jaundice, oedema, gastrointestinal ailments, diarrhoea, dysentery, urinogenital disorder, gall stones, urinary calculi, kidney stone, leucorrhoea, rheumatism, tuberculosis, anaemia, body pain, constipation, skin disease, and as an aphrodisiac. The plant has been reported to contain flavonoids (apigenin, luteolin, ellagic acid, gallic acid and quercetin), alkaloids (asteracanthine and asteracanthicine), triterpenes (lupeol, lupenone, hentricontane and betulin), sterols (stigmasterol and asterol), minerals, amino acids, fatty acids, aliphatic esters and essential oils. Extracts and bioactive compounds from the plant have been found to possess antimicrobial, anthelmintic, antitermite, nephroprotective, hepatoprotective, central nervous system protective, antitumour, antidiabetic, anticataract, antioxidant, haematopoietic, diuretic, antinociceptive, anti-inflammatory, antipyretic, antimotility, aphrodisiac, neuroprotection, anti- endotoxin and anti-urolithiatic activities. For this paper, we reviewed patents, clinical studies, analytical studies and marketed formulations from the earliest found examples from 1887 to the end of 2017. 展开更多
关键词 ETHNOMEDICINE Hygrophila auriculata PHARMACOLOGY PHYTOCHEMICAL
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