Transcriptional plasticity interacts with natural selection in complexways and is crucial for the survival of species under rapid climate change.How 3D genome architecture affects transcriptional plasticity and its in...Transcriptional plasticity interacts with natural selection in complexways and is crucial for the survival of species under rapid climate change.How 3D genome architecture affects transcriptional plasticity and its interaction with genetic adaptation are unclear.We transplanted estuarine oysters to a new environment and found that genes located in active chromatin regions exhibited greater transcriptional plasticity,and changes in these regions were negatively correlatedwith selective signals.展开更多
基金supported by the National Key Research and Development Program of China(2022YFD2400304 to L.L.)the National Natural Science Foundation of China(32101353 to A.L.)+5 种基金the Youth Innovation Promotion Association,Chinese Academy of Sciences(2023215 to A.L.)the Strategic Priority Research Programof the Chinese Academy of Sciences(XDA23050402 to L.L.)the Young Elite Scientists Sponsorship Program by the China Association for Science and Technology(2021QNRC001 to A.L.)the Key Research and Development Programof Shandong(2022LZGC015 to L.L.)the China Agriculture Research System of MOF and MARA(CARS-49 to L.L.)the USDA NIFA Hatch Animal Health Project(NJ32920 to X.G.).
文摘Transcriptional plasticity interacts with natural selection in complexways and is crucial for the survival of species under rapid climate change.How 3D genome architecture affects transcriptional plasticity and its interaction with genetic adaptation are unclear.We transplanted estuarine oysters to a new environment and found that genes located in active chromatin regions exhibited greater transcriptional plasticity,and changes in these regions were negatively correlatedwith selective signals.