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Retention of testicular integrity and testosterone levels upon ingestion of garlic cloves(Allium sativum)in the Sprague-Dawley rat
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作者 Adejoke Elizabeth Memudu Ibukun Dorcas Akinrinade Olalekan Michael Ogundele 《Asian Pacific Journal of Tropical Biomedicine》 SCIE CAS 2015年第4期319-323,共5页
Objective: To investigate the effects of acute and chronic aqueous garlic extract ingestion on testicular cellular integrity and serum testosterone levels.Methods: Twenty(20) male Sprague-Dawley rats weighing an avera... Objective: To investigate the effects of acute and chronic aqueous garlic extract ingestion on testicular cellular integrity and serum testosterone levels.Methods: Twenty(20) male Sprague-Dawley rats weighing an average of 120 g were used.Animals were divided into three groups. Group A served as control(10 rats for 28 and 56 d respectively), while treatment Groups B and C were given 200 mg/kg for Allium sativum(garlic cloves) extract for 28 and 56 d respectively.Results: Histological analysis revealed the presence of all spermatogenic lineages, appearance of proliferative activities in the interstitial cells, as well as increased serum testosterone levels.Conclusions: This study confirmed proliferative and restorative potentials in both acute and chronic garlic ingestion. 展开更多
关键词 ALLIUM sativum TESTIS TESTOSTERONE
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