PURPOSE: To report a case of isolated optic nerve lymphoma diagnosed by optic nerve biopsy. DESIGN: Case report. METHODS: A 66-year-old woman was referred t o the Neuro-Ophthalmology Service because of a decrease in v...PURPOSE: To report a case of isolated optic nerve lymphoma diagnosed by optic nerve biopsy. DESIGN: Case report. METHODS: A 66-year-old woman was referred t o the Neuro-Ophthalmology Service because of a decrease in visual acuity and ri ght optic disk edema. RESULTS: A magnetic resonance image of the brain showed on ly enhancement of the optic nerve. An examination that included ANA, c-ANCA, p -ANCA, Lyme titers, FTA-ABS, ACE level, chest x-ray, and lumbar puncture was negative. Because of rapid progression on clinical examination and serial imagin g, an optic nerve biopsywas performed, which showed B-cell lymphoma. CONCLUSION : Optic nerve lymphoma can be confused with a variety of inflammatory and neopla stic infiltrations of the optic nerve on clinical and radiographic examinations. Optic nerve biopsy can be valuable in diagnosing isolated optic nerve lymphoma if other diagnostic tests are unrevealing, but the procedure carries considerabl e risk of loss of visual acuity and should be recommended judiciously.展开更多
文摘PURPOSE: To report a case of isolated optic nerve lymphoma diagnosed by optic nerve biopsy. DESIGN: Case report. METHODS: A 66-year-old woman was referred t o the Neuro-Ophthalmology Service because of a decrease in visual acuity and ri ght optic disk edema. RESULTS: A magnetic resonance image of the brain showed on ly enhancement of the optic nerve. An examination that included ANA, c-ANCA, p -ANCA, Lyme titers, FTA-ABS, ACE level, chest x-ray, and lumbar puncture was negative. Because of rapid progression on clinical examination and serial imagin g, an optic nerve biopsywas performed, which showed B-cell lymphoma. CONCLUSION : Optic nerve lymphoma can be confused with a variety of inflammatory and neopla stic infiltrations of the optic nerve on clinical and radiographic examinations. Optic nerve biopsy can be valuable in diagnosing isolated optic nerve lymphoma if other diagnostic tests are unrevealing, but the procedure carries considerabl e risk of loss of visual acuity and should be recommended judiciously.
