重症妊娠肝内胆汁淤积症临床危险因素的初步分析

目的研究影响妊娠肝内胆汁淤积症(ICP)严重程度的相关危险因素。方法采用单中心回顾性研究,收集79例ICP患者的临床信息,包括基本情况,肝脏损伤,对分娩和胎儿预后的影响。根据胆汁酸水平,将79例患者分为重症与轻症两组,进行临床数据比较。结果 ICP重症患者的怀孕年龄偏高,重症组平均年龄为(31.0±3.6)岁,轻症组平均年龄为(28.9±4.1)岁,(P=0.034)。妊娠周期中起病时间较早,分别为(250.2±26.57)d vs(258.2±13.27)d,(P=0.079)。HBV感染在重症患者中常见(33.33%vs 14.55%,P=0.056),后两个变量在两组之间差异有边缘性统计学意义(0.05<P<0.10)。绝大部分重症患者(92%)采用剖腹产进行分娩,明显高于轻症组患者(58%),(P=0.006),而新生儿的存活率在轻重症患者之间差异无统计学意义。结论年龄是与ICP严重程度相关的危险因素,起病时间、HBV感染与疾病严重程度的相关性有边缘性统计学意义。

Cooperation, innovation and transition： the new focus of the China Interventional Therapeutics （CIT） congress

Since its inauguration in 2003, China Interventional Therapeutics （CIT） congress has witnessed the growth of percutaneous cardiovascular intervention in China. In 2003 the total number ofpercutaneous coronary intervention （PCI） in China was about 40 000 cases,1 while by CIT＇s 10th anniversary in 2012, the annual number of PCI in China had reached 340 000 cases. CIT has grown along with PCI practice in the country; last year the CIT congress hosted 6000 attendees, including 180 international faculty members and over 750 foreign participants from 42 countries or regions.