Some Implications of Theoretical Relation between RAW and RRW Measures on Risk Reduction Strategies

In using risk-informed approaches for ensuring safety of operating NPPs(nuclear power plants),risk importance measures obtained from PRAs(probabilistic risk assessments)of the plants are integral elements of consideration in many cases.In PSA models and applications associated with NPPs the risk importance of a particular feature(e.g.function,system,component,failure mode or operator action)can be,most generally,divided into two categories:importance with respect to risk increase potential and importance with respect to risk decrease potential.The representative of the first category,as used for practical purposes,is RAW(risk achievement worth).Representative of the second category,as mentioned in consideration of risk importance,is RRW(risk reduction worth).It can be shown that the two risk importance measures,RAW and RRW,are dependent on each other.The only parameter in this mutual dependency is probability of failure of the considered feature.The paper discusses the relation between RAW and RRW and some of its implications,including those on the general strategies for the reduction of risk imposed for the operation of the considered facility.Two general risk reduction strategies which are considered in the discussion are:a)risk reduction by decreasing the failure probability of the considered feature;and b)risk reduction while keeping the failure probability of the considered feature at the same level.Simple examples are provided to illustrate the differences between two strategies and point to main issues and conclusions.

Investigation of the topological shape of bovine serum albumin in solution by small-angle x-ray scattering at Beijing synchrotron radiation facility

This paper reports that at a newly constructed small-angle x-ray scattering station of Beijing Synchrotron Radia- tion Facility, the topological shape of ligand-free bovine serum albumin in solution has been investigated. An appropriate scattering curve is obtained and the calculated value of the gyration radius is 31.2~=t=0.25 ~_ （11=0.1 nm） which is co- incident with other ones＇ results. It finds that the low-resolution structure models obtained by making use of ab initio reconstruction methods are fitting the crystal structure of human serum albumin very well. All of these results perform the potential of the beamline to apply to structural biology studies. The characteristics, the defects, and the improving measures of the station in future are also discussed.