BACKGROUND Vaccine hesitancy is a major challenge in the fight against the coronavirus disease 2019(COVID-19)pandemic.Identifying the sociodemographic factors associated with vaccine acceptance among Nigerians is cruc...BACKGROUND Vaccine hesitancy is a major challenge in the fight against the coronavirus disease 2019(COVID-19)pandemic.Identifying the sociodemographic factors associated with vaccine acceptance among Nigerians is crucial for improving vaccine uptake.AIM To assess the acceptance rate of COVID-19 vaccine and its related determinants among Nigerians.METHODS An online cross-sectional survey(observational study)was conducted between February 2021 and May 2021,using a questionnaire hosted on SurveyMonkey.The invitation to take part in the poll was sent out to participants through social networking platforms.A logistic regression was used to determine which sociodemographic factors were associated with vaccine acceptance constructs.RESULTS A total of 1800 persons responded to the survey,a larger proportion of whom were males(53.9%)and within the age group of 21-30 years(29.4%)and earned an average income of less than$500 per month(43.3%).Only 0.56%of participants had a high perceived risk of COVID-19 infection,while only 1.11%had a perceived risk of dying from COVID-19.The perception rate of the COVID-19 vaccine among participants was 51.1%,while the acceptance rate was 63.9%.There was no significant association between the COVID-19 vaccine acceptance rate and related determinants assessed,particularly age(χ²=3.049,P=0.550),sex(χ²=0.102,P=0.749),average income(χ²=3.802,P=0.875),and religion(χ²=2.819,P=0.420).Participants with chronic conditions demonstrated a higher acceptance rate compared to the general population.CONCLUSION Despite the positive perception observed and substantial vaccine acceptance rate among the study participants,more public health interventions are still needed to enhance vaccine acceptability in Nigeria.展开更多
频域有限差分(finite difference frequency domain,FDFD)方法是地震波场模拟的常用方法,FDFD地震波场模拟的关键之一是构造能有效压制数值频散的FDFD系数。在已有的构造地震波场模拟FDFD系数的方法中,随一个网格内的波长个数变化的自适...频域有限差分(finite difference frequency domain,FDFD)方法是地震波场模拟的常用方法,FDFD地震波场模拟的关键之一是构造能有效压制数值频散的FDFD系数。在已有的构造地震波场模拟FDFD系数的方法中,随一个网格内的波长个数变化的自适应FDFD系数可以最大程度地压制数值频散。目前计算自适应FDFD系数的方法涉及角度积分、共轭梯度优化、顺序初值选取、光滑正则化等问题,不仅较难实现而且计算效率较低。为了简化自适应FDFD系数的计算并提高相应计算效率,本文提出一种新的计算自适应FDFD系数的方法。所提方法首先将不同离散传播角度的平面波解代入FDFD格式,构造相应的最小二乘问题。由于该最小二乘问题较为病态,常规的基于正规方程组的求解方法难以得到光滑的自适应FDFD系数,本文提出通过QR矩阵分解求解相应超定线性方程组来求解该最小二乘问题。相比已有的基于角度积分、共轭梯度优化、顺序初值选取的计算自适应FDFD系数的方法,所提方法在可以得到光滑自适应FDFD系数的基础上,不仅计算过程更简洁,且计算效率明显提高。数值波场模拟结果表明,基于QR矩阵分解的自适应系数FDFD方法可以达到与基于角度积分、共轭梯度优化、顺序初值选取的自适应系数FDFD方法相同的精度,同时所需的计算时间更少。展开更多
In heterogeneous natural gas reservoirs, gas is generally present as small patchlike pockets embedded in the water-saturated host matrix. This type of heterogeneity, also called "patchy saturation", causes s...In heterogeneous natural gas reservoirs, gas is generally present as small patchlike pockets embedded in the water-saturated host matrix. This type of heterogeneity, also called "patchy saturation", causes significant seismic velocity dispersion and attenuation. To establish the relation between seismic response and type of fluids, we designed a rock physics model for carbonates. First, we performed CT scanning and analysis of the fluid distribution in the partially saturated rocks. Then, we predicted the quantitative relation between the wave response at different frequency ranges and the basic lithological properties and pore fluids. A rock physics template was constructed based on thin section analysis of pore structures and seismic inversion. This approach was applied to the limestone gas reservoirs of the right bank block of the Amu Darya River. Based on poststack wave impedance and prestack elastic parameter inversions, the seismic data were used to estimate rock porosity and gas saturation. The model results were in good agreement with the production regime of the wells.展开更多
We performed ultrasonic experiments in specimens from a tight oil reservoir. The P-wave attenuation of fl uid-saturated specimens was estimated by the spectral ratio method. The results suggest that at ultrasonic freq...We performed ultrasonic experiments in specimens from a tight oil reservoir. The P-wave attenuation of fl uid-saturated specimens was estimated by the spectral ratio method. The results suggest that at ultrasonic frequencies, most specimens have stronger attenuation under gas-saturated conditions than at water- or oil-saturated conditions. The P-wave attenuation positively correlates with permeability. Scanning electron microscopy observations and the triple-porosity structure model were used to simulate the wave propagation. The P-wave velocity dispersion and attenuation are discussed on the basis of the Biot, Biot– Rayleigh double-porosity medium, and the triple-porosity structure models. The results suggest that the Biot and Biot–Rayleigh models cannot explain the attenuation, whereas the triple-porosity structure model is in agreement with the experimental data. Furthermore, we infer that microcracks are common in a porosity of 5%–10%, and the size of microcracks increases in samples with higher porosity. However, the volume ratios of microcracks and clay inclusions remain constant regardless of porosity variations. The size of microcracks is signifi cantly larger than the clay inclusions, and the bulk modulus of microcracks is lower than the bulk modulus of clays.展开更多
Microbial enhanced oil recovery (MEOR) methods apply injection of bacteria to depleted oil reservoirs to produce oil, which had remained unrecovered after the conventional methods of production. The ability ofthermo...Microbial enhanced oil recovery (MEOR) methods apply injection of bacteria to depleted oil reservoirs to produce oil, which had remained unrecovered after the conventional methods of production. The ability ofthermophilic anaerobic bacteria to produce gas as the main mechanism in potential MEOR in high salinities of 70-100 g/L was investigated in this study. Maximum gas production of up to 350 mL per 700 mL of salty solution was produced at a salinity of 90 g/L stably during 2-4 days of experiment. The experimental results were upscaled to the Snorre Oilfield, Norway, and simulated using ECLIPSE software for 27 months. The best scenarios showed that the increase in oil recovery on average was at 21% and 17.8% respectively. This study demonstrated that anaerobic bacteria used in biogas plants could be an attractive candidate for MEOR implementation due to their ability to withstand high temperature and salinity, and produce gas in large volumes.展开更多
The wave-induced local fluid flow mechanism is relevant to the complex heterogeneity of pore structures in rocks.The analysis of the local fluid flow mechanism is useful for accurately describing the wave propagation ...The wave-induced local fluid flow mechanism is relevant to the complex heterogeneity of pore structures in rocks.The analysis of the local fluid flow mechanism is useful for accurately describing the wave propagation characteristics in reservoir rocks.In the exploration and production of hydrocarbon reservoirs,the real stratum may be partially saturated with a multi-phase fluid mixture in general.Therefore,it is of great significance to investigate the wave velocity dispersion and attenuation features in relation to pore structures and fluids.In this work,the characteristics of fabric microstructures are obtained on the basis of pressure dependency of dry rock moduli using the effective medium theory.A novel anelasticity theoretical model for the wave propagation in a partially-saturated medium is presented by combining the extended Gurevich squirt-flow model and White patchysaturation theory.Numerical simulations are used to analyze wave propagation characteristics that depend on water saturation,external patchy diameter,and viscosity.We consider a tight sandstone from the Qingyang area of the Ordos Basin in west China and perform ultrasonic measurements under partial saturation states and different confining pressures,where the basic properties of the rock are obtained at the full gas saturation.The comparison of experimental data and theoretical modeling results shows a fairly good agreement,indicating that the new theory is effective.展开更多
The strongest documented seismic disaster ever occurred in the Po Plain area (January 3, 1117, M = 6.5) involved significant damage over a large zone. The genetic mechanism of such </span><span style="fo...The strongest documented seismic disaster ever occurred in the Po Plain area (January 3, 1117, M = 6.5) involved significant damage over a large zone. The genetic mechanism of such </span><span style="font-family:Verdana;">an </span><span style="font-family:Verdana;">event, most probably caused by more than one earthquake, is still </span><span style="font-family:Verdana;">an </span><span style="font-family:Verdana;">object of debate. Above all, the sources so far proposed cannot account for significant features of the observed macroseismic field. In this work, we suggest that the damage in the Verona zone was caused by the activation of a fault in the Lessini tectonic district, while damage in the central Po Plain may be related to a thrust fault located beneath the Giudicarie belt. The effects felt in northern Tuscany might derive from the seismic activ</span><span style="font-family:Verdana;">ation</span><span style="font-family:""><span style="font-family:Verdana;"> of the pre</span><span style="font-family:Verdana;">sumed SW-ward buried prolongation of the Giudicarie fault. The presence of such transpressional lithospheric discontinuity in the Adriatic domain since the upper Miocene and its reactivation (Pliocene-Pleistocene</span><span style="font-family:Verdana;">) as a thrust zone is mainly suggested by an accurate analysis of the observed deformation pattern in the central Mediterranean region. The proposed Giudicarie source may also help to explain the damage observed in the central Po Plain on December 25, 1222, which is not compatible with the seismic sources so far proposed.展开更多
Detection of small cancer biomarkers with low molecular weight and a low concentration range has always been challenging yet urgent in many clinical applications such as diagnosing early-stage cancer,monitoring treatm...Detection of small cancer biomarkers with low molecular weight and a low concentration range has always been challenging yet urgent in many clinical applications such as diagnosing early-stage cancer,monitoring treatment and detecting relapse.Here,a highly enhanced plasmonic biosensor that can overcome this challenge is developed using atomically thin two-dimensional phase change nanomaterial.By precisely engineering the configuration with atomically thin materials,the phase singularity has been successfully achieved with a significantly enhanced lateral position shift effect.Based on our knowledge,it is the first experimental demonstration of a lateral position signal change>340μm at a sensing interface from all optical techniques.With this enhanced plasmonic effect,the detection limit has been experimentally demonstrated to be 10^(-15) mol L^(−1) for TNF-α cancer marker,which has been found in various human diseases including inflammatory diseases and different kinds of cancer.The as-reported novel integration of atomically thin Ge_(2)Sb_(2)Te_(5) with plasmonic substrate, which results in a phase singularity and thus a giant lateral position shift, enables the detection of cancer markers with low molecular weight at femtomolar level. These results will definitely hold promising potential in biomedical application and clinical diagnostics.展开更多
Aerosol-cloud-radiation interactions represent one of the largest uncertainties in the current climate assessment. Much of the complexity arises from the non-monotonic responses of clouds, precipitation and radiative ...Aerosol-cloud-radiation interactions represent one of the largest uncertainties in the current climate assessment. Much of the complexity arises from the non-monotonic responses of clouds, precipitation and radiative fluxes to aerosol perturbations under various meteorological conditions. In this study, an aerosol-aware WRF model is used to investigate the microphysical and radiative effects of aerosols in three weather systems during the March 2000 Cloud Intensive Observational Period campaign at the US Southern Great Plains. Three simulated cloud ensembles include a low-pressure deep convective cloud system, a collection of less-precipitating stratus and shallow cumulus, and a cold frontal passage. The WRF simulations are evaluated by several ground-based measurements. The microphysical properties of cloud hydrometeors, such as their mass and number concentrations, generally show monotonic trends as a function of cloud condensation nuclei concentrations. Aerosol radiative effects do not influence the trends of cloud microphysics, except for the stratus and shallow cumulus cases where aerosol semi-direct effects are identified. The precipitation changes by aerosols vary with the cloud types and their evolving stages, with a prominent aerosol invigoration effect and associated enhanced precipitation from the convective sources. The simulated aerosol direct effect suppresses precipitation in all three cases but does not overturn the aerosol indirect effect. Cloud fraction exhibits much smaller sensitivity (typically less than 2%) to aerosol perturbations, and the responses vary with aerosol concentrations and cloud regimes. The surface shortwave radiation shows a monotonic decrease by increasing aerosols, while the magnitude of the decrease depends on the cloud type.展开更多
Few seismic exploration work was carried out in Tibetan Plateau due to the characteristics of alpine hypoxia and harsh environmental protection needs.Complex near surface geological conditions,especially the signal sh...Few seismic exploration work was carried out in Tibetan Plateau due to the characteristics of alpine hypoxia and harsh environmental protection needs.Complex near surface geological conditions,especially the signal shielding and static correction of permafrost make the quality of seismic data is not ideal,the signal to noise ratio(SNR)is low,and deep target horizon imaging is difficult.These data cannot provide high quality information for oil and gas geological survey and structural sedimentary research in the area.To solve the issue of seismic exploration in Tibetan Plateau,this test used low frequency vibroseis wide-line and high-density acquisition scheme.In view of the actual situation of the study area,the terrain,the source and the diff erent observation system were simulated,and the processing technique was adopted to improve the quality of seismic data.Low-frequency components with a minimum of 1.5Hz of vibroseis ensure the deep geological target imaging quality in the area,the seismic profi le wave group is clear,and the SNR is relatively high,which can meet the needs of oil and gas exploration.Seismic data can provide the support for the development of oil and gas survey in the Tibet plateau.展开更多
This study aims to determine the relationships between local meteorological conditions,proglacial river discharge and biogeochemical processes operating in a periglacial basin located in the Polar Ural mountain range,...This study aims to determine the relationships between local meteorological conditions,proglacial river discharge and biogeochemical processes operating in a periglacial basin located in the Polar Ural mountain range, Russia. Fieldwork was conducted in the catchment of Obruchev Glacier(13 km2) during the summer peak flow period in 2008. River discharge was dominated by snowmelt and changed from 3300 l s-1 to less than 1000 l s-1. The mean daily air temperatures of stations situated in the mountain tundra and near Obruchev Glacier from July 11 th to August 1st 2008 were 14.4°C and 10.3°C, respectively. The glacial river had low total dissolved solids varying from 4.5 to 9 mg l-1 and coefficients of correlation between Na+ and Cl-, K+ and Cl-, as well as NH4+ and Cl- were 0.94, 0.90 and 0.84, respectively. Rainfall events affected the snowmelt initiation and provided an essential part of the discharge during the intense snowmelt period, which occurred from July 11 th to July 18 th 2008. Data showed that Na+ and K+ in the surface water derived from snowmelt rather than chemical weathering of silicates. Also, it was obtained that NO3- derived from the melting snowpack, whereas ammonification occurring under the snowpacks was the primary source for NH4+.展开更多
EVs (electric vehicles) have been widely accepted as a promising solution for reducing oil consumption, air pollution and greenhouse gas emission. The number of EVs is growing very fast over the years. However, the ...EVs (electric vehicles) have been widely accepted as a promising solution for reducing oil consumption, air pollution and greenhouse gas emission. The number of EVs is growing very fast over the years. However, the high adoption of EVs will impose a burden on the power system, especially for neighborhood level network. In this paper, we propose a mixed control framework for EV charging scheduling to mitigate its impact on the power network. A metric for modeling customer's satisfaction is also proposed to compare the user satisfaction for different algorithms. The impacts of the proposed algorithms on EV charging cost, EV penetration and peak power reduction are evaluated with real data for a neighborhood level network. The simulation results demonstrate the effectiveness of the proposed algorithms.展开更多
In this paper we present the most important definitions and results of the theory of parabolic-like mappings, and we will give an example. The proofs of the results can be found in [2,4] and [3].
基金supported by the Natural Science Foundation of Jiangsu Province(Grant No.BK20200021)the National Natural Science Foundation of China(Grant No.42174161 and 41974123)the Natural Science Foundation of Heilongjiang Province of China(YQ2023D005).
文摘BACKGROUND Vaccine hesitancy is a major challenge in the fight against the coronavirus disease 2019(COVID-19)pandemic.Identifying the sociodemographic factors associated with vaccine acceptance among Nigerians is crucial for improving vaccine uptake.AIM To assess the acceptance rate of COVID-19 vaccine and its related determinants among Nigerians.METHODS An online cross-sectional survey(observational study)was conducted between February 2021 and May 2021,using a questionnaire hosted on SurveyMonkey.The invitation to take part in the poll was sent out to participants through social networking platforms.A logistic regression was used to determine which sociodemographic factors were associated with vaccine acceptance constructs.RESULTS A total of 1800 persons responded to the survey,a larger proportion of whom were males(53.9%)and within the age group of 21-30 years(29.4%)and earned an average income of less than$500 per month(43.3%).Only 0.56%of participants had a high perceived risk of COVID-19 infection,while only 1.11%had a perceived risk of dying from COVID-19.The perception rate of the COVID-19 vaccine among participants was 51.1%,while the acceptance rate was 63.9%.There was no significant association between the COVID-19 vaccine acceptance rate and related determinants assessed,particularly age(χ²=3.049,P=0.550),sex(χ²=0.102,P=0.749),average income(χ²=3.802,P=0.875),and religion(χ²=2.819,P=0.420).Participants with chronic conditions demonstrated a higher acceptance rate compared to the general population.CONCLUSION Despite the positive perception observed and substantial vaccine acceptance rate among the study participants,more public health interventions are still needed to enhance vaccine acceptability in Nigeria.
基金supported by the National Natural Science Foundation of China(No.42174161,No.41974123)China Postdoctoral Science Foundation(No.2022M711004)+1 种基金China National Petroleum Corporation Exploration and Development Research Institute Open Fund(No.822102016)the Jiangsu Province Science Fund for Distinguished Young Scholars(No.BK20200021).
文摘频域有限差分(finite difference frequency domain,FDFD)方法是地震波场模拟的常用方法,FDFD地震波场模拟的关键之一是构造能有效压制数值频散的FDFD系数。在已有的构造地震波场模拟FDFD系数的方法中,随一个网格内的波长个数变化的自适应FDFD系数可以最大程度地压制数值频散。目前计算自适应FDFD系数的方法涉及角度积分、共轭梯度优化、顺序初值选取、光滑正则化等问题,不仅较难实现而且计算效率较低。为了简化自适应FDFD系数的计算并提高相应计算效率,本文提出一种新的计算自适应FDFD系数的方法。所提方法首先将不同离散传播角度的平面波解代入FDFD格式,构造相应的最小二乘问题。由于该最小二乘问题较为病态,常规的基于正规方程组的求解方法难以得到光滑的自适应FDFD系数,本文提出通过QR矩阵分解求解相应超定线性方程组来求解该最小二乘问题。相比已有的基于角度积分、共轭梯度优化、顺序初值选取的计算自适应FDFD系数的方法,所提方法在可以得到光滑自适应FDFD系数的基础上,不仅计算过程更简洁,且计算效率明显提高。数值波场模拟结果表明,基于QR矩阵分解的自适应系数FDFD方法可以达到与基于角度积分、共轭梯度优化、顺序初值选取的自适应系数FDFD方法相同的精度,同时所需的计算时间更少。
基金sponsored by the NSFC(41104066)973 Program of China(No.2014CB239006)+1 种基金NSTMP of China(Nos.2011ZX05004-003 and 2011ZX05029-003)12th 5-Year Basic Research Program of CNPC(No.2011A-3601)
文摘In heterogeneous natural gas reservoirs, gas is generally present as small patchlike pockets embedded in the water-saturated host matrix. This type of heterogeneity, also called "patchy saturation", causes significant seismic velocity dispersion and attenuation. To establish the relation between seismic response and type of fluids, we designed a rock physics model for carbonates. First, we performed CT scanning and analysis of the fluid distribution in the partially saturated rocks. Then, we predicted the quantitative relation between the wave response at different frequency ranges and the basic lithological properties and pore fluids. A rock physics template was constructed based on thin section analysis of pore structures and seismic inversion. This approach was applied to the limestone gas reservoirs of the right bank block of the Amu Darya River. Based on poststack wave impedance and prestack elastic parameter inversions, the seismic data were used to estimate rock porosity and gas saturation. The model results were in good agreement with the production regime of the wells.
基金the Specially Appointed Professor Program of Jiangsu Province, China,the National Natural Science Foundation of China (No. 41704109)the Fundamental Research Funds for the Central Universities, China.(No. 2016B13114).
文摘We performed ultrasonic experiments in specimens from a tight oil reservoir. The P-wave attenuation of fl uid-saturated specimens was estimated by the spectral ratio method. The results suggest that at ultrasonic frequencies, most specimens have stronger attenuation under gas-saturated conditions than at water- or oil-saturated conditions. The P-wave attenuation positively correlates with permeability. Scanning electron microscopy observations and the triple-porosity structure model were used to simulate the wave propagation. The P-wave velocity dispersion and attenuation are discussed on the basis of the Biot, Biot– Rayleigh double-porosity medium, and the triple-porosity structure models. The results suggest that the Biot and Biot–Rayleigh models cannot explain the attenuation, whereas the triple-porosity structure model is in agreement with the experimental data. Furthermore, we infer that microcracks are common in a porosity of 5%–10%, and the size of microcracks increases in samples with higher porosity. However, the volume ratios of microcracks and clay inclusions remain constant regardless of porosity variations. The size of microcracks is signifi cantly larger than the clay inclusions, and the bulk modulus of microcracks is lower than the bulk modulus of clays.
文摘Microbial enhanced oil recovery (MEOR) methods apply injection of bacteria to depleted oil reservoirs to produce oil, which had remained unrecovered after the conventional methods of production. The ability ofthermophilic anaerobic bacteria to produce gas as the main mechanism in potential MEOR in high salinities of 70-100 g/L was investigated in this study. Maximum gas production of up to 350 mL per 700 mL of salty solution was produced at a salinity of 90 g/L stably during 2-4 days of experiment. The experimental results were upscaled to the Snorre Oilfield, Norway, and simulated using ECLIPSE software for 27 months. The best scenarios showed that the increase in oil recovery on average was at 21% and 17.8% respectively. This study demonstrated that anaerobic bacteria used in biogas plants could be an attractive candidate for MEOR implementation due to their ability to withstand high temperature and salinity, and produce gas in large volumes.
基金supported by the National Natural Science Foundation of China(Grant no.41704109)the Jiangsu Province Outstanding Youth Fund Project(Grant no.BK20200021).
文摘The wave-induced local fluid flow mechanism is relevant to the complex heterogeneity of pore structures in rocks.The analysis of the local fluid flow mechanism is useful for accurately describing the wave propagation characteristics in reservoir rocks.In the exploration and production of hydrocarbon reservoirs,the real stratum may be partially saturated with a multi-phase fluid mixture in general.Therefore,it is of great significance to investigate the wave velocity dispersion and attenuation features in relation to pore structures and fluids.In this work,the characteristics of fabric microstructures are obtained on the basis of pressure dependency of dry rock moduli using the effective medium theory.A novel anelasticity theoretical model for the wave propagation in a partially-saturated medium is presented by combining the extended Gurevich squirt-flow model and White patchysaturation theory.Numerical simulations are used to analyze wave propagation characteristics that depend on water saturation,external patchy diameter,and viscosity.We consider a tight sandstone from the Qingyang area of the Ordos Basin in west China and perform ultrasonic measurements under partial saturation states and different confining pressures,where the basic properties of the rock are obtained at the full gas saturation.The comparison of experimental data and theoretical modeling results shows a fairly good agreement,indicating that the new theory is effective.
文摘The strongest documented seismic disaster ever occurred in the Po Plain area (January 3, 1117, M = 6.5) involved significant damage over a large zone. The genetic mechanism of such </span><span style="font-family:Verdana;">an </span><span style="font-family:Verdana;">event, most probably caused by more than one earthquake, is still </span><span style="font-family:Verdana;">an </span><span style="font-family:Verdana;">object of debate. Above all, the sources so far proposed cannot account for significant features of the observed macroseismic field. In this work, we suggest that the damage in the Verona zone was caused by the activation of a fault in the Lessini tectonic district, while damage in the central Po Plain may be related to a thrust fault located beneath the Giudicarie belt. The effects felt in northern Tuscany might derive from the seismic activ</span><span style="font-family:Verdana;">ation</span><span style="font-family:""><span style="font-family:Verdana;"> of the pre</span><span style="font-family:Verdana;">sumed SW-ward buried prolongation of the Giudicarie fault. The presence of such transpressional lithospheric discontinuity in the Adriatic domain since the upper Miocene and its reactivation (Pliocene-Pleistocene</span><span style="font-family:Verdana;">) as a thrust zone is mainly suggested by an accurate analysis of the observed deformation pattern in the central Mediterranean region. The proposed Giudicarie source may also help to explain the damage observed in the central Po Plain on December 25, 1222, which is not compatible with the seismic sources so far proposed.
基金We thank Shiyue Liu from School of Life Sciences in The Chinese University of Hong Kong for helpful discussions.This work is supported under the PROCORE-France/Hong Kong Joint Research Scheme(F-CUHK402/19)the Research Grants Council,Hong Kong Special Administration Region(AoE/P-02/12,14210517,14207419,N_CUHK407/16)the European Union’s Horizon 2020 research and innovation programme under the Marie Sklodowska-Curie Grant Agreement No.798916.Y.Wang is supported under the Hong Kong PhD Fellowship Scheme.
文摘Detection of small cancer biomarkers with low molecular weight and a low concentration range has always been challenging yet urgent in many clinical applications such as diagnosing early-stage cancer,monitoring treatment and detecting relapse.Here,a highly enhanced plasmonic biosensor that can overcome this challenge is developed using atomically thin two-dimensional phase change nanomaterial.By precisely engineering the configuration with atomically thin materials,the phase singularity has been successfully achieved with a significantly enhanced lateral position shift effect.Based on our knowledge,it is the first experimental demonstration of a lateral position signal change>340μm at a sensing interface from all optical techniques.With this enhanced plasmonic effect,the detection limit has been experimentally demonstrated to be 10^(-15) mol L^(−1) for TNF-α cancer marker,which has been found in various human diseases including inflammatory diseases and different kinds of cancer.The as-reported novel integration of atomically thin Ge_(2)Sb_(2)Te_(5) with plasmonic substrate, which results in a phase singularity and thus a giant lateral position shift, enables the detection of cancer markers with low molecular weight at femtomolar level. These results will definitely hold promising potential in biomedical application and clinical diagnostics.
基金support provided by NASA ROSES14-ACMAPNSF (Award No. 1700727)+1 种基金supported by the US DOE ASR programsupport of the Jet Propulsion Laboratory, California Institute of Technology, under contract with NASA
文摘Aerosol-cloud-radiation interactions represent one of the largest uncertainties in the current climate assessment. Much of the complexity arises from the non-monotonic responses of clouds, precipitation and radiative fluxes to aerosol perturbations under various meteorological conditions. In this study, an aerosol-aware WRF model is used to investigate the microphysical and radiative effects of aerosols in three weather systems during the March 2000 Cloud Intensive Observational Period campaign at the US Southern Great Plains. Three simulated cloud ensembles include a low-pressure deep convective cloud system, a collection of less-precipitating stratus and shallow cumulus, and a cold frontal passage. The WRF simulations are evaluated by several ground-based measurements. The microphysical properties of cloud hydrometeors, such as their mass and number concentrations, generally show monotonic trends as a function of cloud condensation nuclei concentrations. Aerosol radiative effects do not influence the trends of cloud microphysics, except for the stratus and shallow cumulus cases where aerosol semi-direct effects are identified. The precipitation changes by aerosols vary with the cloud types and their evolving stages, with a prominent aerosol invigoration effect and associated enhanced precipitation from the convective sources. The simulated aerosol direct effect suppresses precipitation in all three cases but does not overturn the aerosol indirect effect. Cloud fraction exhibits much smaller sensitivity (typically less than 2%) to aerosol perturbations, and the responses vary with aerosol concentrations and cloud regimes. The surface shortwave radiation shows a monotonic decrease by increasing aerosols, while the magnitude of the decrease depends on the cloud type.
基金This work was supported by Nation key R&D program(No.2016YFC060110305)Geological and mineral investigation and evaluation special project(No.DD20160160 and No.DD20160181).
文摘Few seismic exploration work was carried out in Tibetan Plateau due to the characteristics of alpine hypoxia and harsh environmental protection needs.Complex near surface geological conditions,especially the signal shielding and static correction of permafrost make the quality of seismic data is not ideal,the signal to noise ratio(SNR)is low,and deep target horizon imaging is difficult.These data cannot provide high quality information for oil and gas geological survey and structural sedimentary research in the area.To solve the issue of seismic exploration in Tibetan Plateau,this test used low frequency vibroseis wide-line and high-density acquisition scheme.In view of the actual situation of the study area,the terrain,the source and the diff erent observation system were simulated,and the processing technique was adopted to improve the quality of seismic data.Low-frequency components with a minimum of 1.5Hz of vibroseis ensure the deep geological target imaging quality in the area,the seismic profi le wave group is clear,and the SNR is relatively high,which can meet the needs of oil and gas exploration.Seismic data can provide the support for the development of oil and gas survey in the Tibet plateau.
基金supported by the Institute of Geography and Spatial Management at Jagiellonian University
文摘This study aims to determine the relationships between local meteorological conditions,proglacial river discharge and biogeochemical processes operating in a periglacial basin located in the Polar Ural mountain range, Russia. Fieldwork was conducted in the catchment of Obruchev Glacier(13 km2) during the summer peak flow period in 2008. River discharge was dominated by snowmelt and changed from 3300 l s-1 to less than 1000 l s-1. The mean daily air temperatures of stations situated in the mountain tundra and near Obruchev Glacier from July 11 th to August 1st 2008 were 14.4°C and 10.3°C, respectively. The glacial river had low total dissolved solids varying from 4.5 to 9 mg l-1 and coefficients of correlation between Na+ and Cl-, K+ and Cl-, as well as NH4+ and Cl- were 0.94, 0.90 and 0.84, respectively. Rainfall events affected the snowmelt initiation and provided an essential part of the discharge during the intense snowmelt period, which occurred from July 11 th to July 18 th 2008. Data showed that Na+ and K+ in the surface water derived from snowmelt rather than chemical weathering of silicates. Also, it was obtained that NO3- derived from the melting snowpack, whereas ammonification occurring under the snowpacks was the primary source for NH4+.
文摘EVs (electric vehicles) have been widely accepted as a promising solution for reducing oil consumption, air pollution and greenhouse gas emission. The number of EVs is growing very fast over the years. However, the high adoption of EVs will impose a burden on the power system, especially for neighborhood level network. In this paper, we propose a mixed control framework for EV charging scheduling to mitigate its impact on the power network. A metric for modeling customer's satisfaction is also proposed to compare the user satisfaction for different algorithms. The impacts of the proposed algorithms on EV charging cost, EV penetration and peak power reduction are evaluated with real data for a neighborhood level network. The simulation results demonstrate the effectiveness of the proposed algorithms.
文摘In this paper we present the most important definitions and results of the theory of parabolic-like mappings, and we will give an example. The proofs of the results can be found in [2,4] and [3].