Prescription of Antibiotics in Oral-Dental Practice: Case of the Dental Practice at the Coyah Prefectoral Hospital in the Republic of Guinea 2019-2020

Introduction: Antibiotics are medications that have the property of destroying bacteria or preventing their proliferation. The aim of this study is to evaluate antibiotic prescriptions in oral practice: case of the dental office of the Coyah prefectural hospital. Methods: This is a descriptive cross-sectional study which took place from August 2019 to January 2020 inclusive, i.e. a duration of six (6) months, during which 400 patients were identified. Results: Our results revealed a frequency of 70% of antibiotic prescriptions. The 16 - 25-year-old age group was the most dismayed, at 47.25% and with an average age of 27.78 years. Men represent 55% compared to 45% of women, i.e. sex ratio of 1.22. Pulp gangrene was the most common pathology in 55% of cases. The most prescribed family was Betalactamine or 61.71% and the most represented molecules were Amoxicillin with 56.10% followed by Metronidazole or 34.16%. And the favorable prognosis was observed in 99% of cases. Conclusion: Prescription should always be based on the benefit-risk ratio. This prescription by practitioners aims to prevent or eradicate infections and pain in order to obtain a good therapeutic result.

Study on the Treatment of Reusable Care Equipment in Public and Private Dental Practices in the City of Conakry

Introduction: The effective sterilization of reusable instruments in dental care is a crucial issue for public health. The aim of this study was to contribute to improving the processing conditions of reusable care instruments in dental practices in the city of Conakry. Methods: We carried out an observational and cross-sectional study of a descriptive type lasting three months from January to April 2022 in public and private dental practices approved for activities. Results: A total of 48 dental practices were surveyed, including 7 public and 41 private. 91.67% had the trays for instrument sterilization. 77.08% had a sterilization device. The instruments were: cleaned 100%, disinfected 70.83%, sterilized 20.83% and 20.83% reused the instruments without being sterilized. 72.97% sterilized the instruments at the end of the day. 50% of respondents declared that there were six stages of sterilization. According to standard standards, one dental office or 2.70% respected the normal sterilization process and 13.51% respected the duration and temperature. The storage quality was inadequate at 95.83%. 95.83% of dental practices are at high risk of contamination. The difficulties encountered by staff in daily activity during our study were lack of hygienists (87.50%), insufficient material resources (58.33%), and lack of protocol procedure (45.83%). Conclusion: This study allowed us to note shortcomings of dental surgeons in the process of processing reusable care materials.

The Dental Absces: Epidemiological, Clinical and Therapeutic Aspects at the Dental Office of the Prefectoral Hospital of Siguiri in 2021 in the Republic of Guinea

Introduction: A dental abscess is a collection of pus located in the tissues surrounding the tooth roots. The aim of this work is to describe the epidemiological, clinical and therapeutic aspects of dental abscess in order to contribute to the management of patients suffering from this pathology at the dental office of the Siguiri Prefectural Hospital. Methods: This was a retrospective descriptive study lasting 2 months carried out on the registers of patients received between October 2017 and October 2020 at the dental office of the Siguiri prefectural hospital. Results: 4690 patient files were identified during the study, of which 546 met our selection criteria, i.e. a frequency of 11.64%. During our study, we found 51.83% female compared to 48.17% male, i.e. a sex ratio of 1.07. 54.21% of our patients resided in rural communes compared to 45.76% for the urban commune. The age group most affected was that of 16 - 25 years old or 33.69%. Swelling, pain and functional discomfort were the reasons for consultation in all patients followed by other associated reasons in 41.21%. The premolar-molar group was the most represented, i.e. 86.70%. 80.04% of our patients presented an acute abscess compared to 19.96% of chronic cases. Antibiotic, analgesic, and mouthwash were prescribed in all patients during the study followed by 96.37% of cases prescription of steroidal anti-inflammatory drugs. 93.04% of causal teeth were extracted followed by 6.78% of cases of conservative treatment in our study. In our study, 80.95% of our patients had a good post-therapeutic outcome. Conclusion: This study highlights the need for prevention and early management of dental abscesses.

Klippel-feil:A syndrome in the occipital-cervical spine field and its dentofacial manifestations

Klippel-Feil syndrome(KFS) is defined by congenital cervical vertebral spine fusion and is seen with a wide spectrum of dental manifestations and craniofacial profiles. Previous studies on lateral cephalograms have documented an association between fusion of the cervicalvertebrae and deviations in the craniofacial profile in non-syndromic patients with severe malocclusion. To our knowledge, no previous studies have described the craniofacial profile including the cranial base of KFS patients on lateral cephalograms. Therefore KFS and its craniofacial and dental manifestations were described according to existing literature and additionally the craniofacial profile and cranial base was analysed on lateral cephalograms of two patients with KFS. According to the literature the dental manifestations of KFS-patients included oligodontia, overjet, cross bite, open bite and deep bite. The craniofacial profile was clinically described as reduced lower facial height, midfacial hypoplasia, and mandibular prognathia. The analyses of the two lateral cephalograms showed increased mandibular inclination, increased vertical jaw-relationship, increased jaw angle and maxillary retrognathia. The cranial base was normal in both cases. The sagittal jaw relationship and mandibular prognathia varied between the two cases. The literature review and the analyses of the two lateral cephalograms have shown that deviations in the occipital and cervical spine field as KFS were associated with deviations in the teeth and craniofacial profile.

Tooth agenesis and craniofacial morphology in preorthodontic children with and without morphological deviations in the upper cervical spine

AIM: To analyze differences in prevalence and pattern of tooth agenesis and craniofacial morphology between non syndromic children with tooth agenesis with and without upper cervical spine morphological deviations and to analyze associations between craniofacial morphology and tooth agenesis in the two groups together. METHODS: One hundred and twenty-six pre-orthodontic children with tooth agenesis were divided into two groups with(19 children, mean age 11.9) and without(107 children, mean age 11.4) upper spine morphological deviations. Visual assessment of upper spine morphology and measurements of craniofacial morphology were performed on lateral cephalograms. Tooth agenesis was evaluated from orthopantomograms.RESULTS: No significant differences in tooth agenesis and craniofacial morphology were found between children with and without upper spine morphological deviations(2.2 ± 1.6 vs 1.94 ± 1.2, P > 0.05) but a tendency to a different tooth agenesis pattern were seen in children with morphological deviations in the upper spine. In the total group tooth agenesis was associated with the cranial base angle(n-s-ba, r = 0.23,P < 0.01), jaw angle(ML/RLar, r = 0.19, P < 0.05), mandibular inclination(NSL/ML, r =-0.21, P < 0.05), mandibular prognathia(s-n-pg, r = 0.25, P < 0.01), sagittal jaw relationship(ss-n-pg, r =-0.23, P < 0.5), overjet(r =-0.23, P < 0.05) and overbite(r =-0.25, P < 0.01). CONCLUSION: Etiology of tooth agenesis in children with upper spine morphological deviations was discussed. The results may be valuable for the early diagnosis and treatment planning of non syndromic children with tooth agenesis.

Polyamide Fibers Covered with Chlorhexidine: Thermodynamic Aspects

Results of dynamic and equilibrium of sorption of a reactive dye Remazol Brilliant Blue, and a bactericidal agent, Digluconate of Chlorhexidine over Polyamide fibers are presented with the aim of supplying the fiber with bactericidal properties. However, adsorption of Chlorhexidine onto Polyamide is scarce due to the lack of interactions between the reactive groups of the fiber and the antiseptic molecule. Therefore, in order to provide the fiber surface with anionic groups, fiber has been previously dyed with Remazol Brilliant Blue which increases the negative charge of the fiber surface due to the presence of its sulfonate end groups. Thermodynamic parameters of equilibrium sorption in the two situations, fiber/dye and fiber-dye/Chlorhexidine, have been analyzed, as function of the temperature, pH and concentration of the dye in the pretreatment. Results show that when sorption of Remazol Brilliant Blue reaches the value of about 50 mmol/ kg at the higher temperature and concentration tested, the amount of Chlorhexidine adsorbed exhibits its maximum value which is 6 mmol/kg. Both processes, adsorption of Remazol Brilliant Blue and adsorption of Chlorhexidine, fit well to Langmuir adsorption model, suggesting the existence of some kinds of specific interactions between adsorbent and adsorbate. Thermodynamic functions show that the interaction is endothermic and spontaneous in all the rage of temperature tested. The kinetic studies show that sorption of Remazol Brilliant Blue is better described by pseudo-first order model, while sorption of Chlorhexidine fits better to pseudo-second order model, and seems to be quicker process. According to the obtained results, chemical interaction between the vinyl-sulfone group of Remazol Brilliant Blue and the amine groups of Polyamide fiber, followed by electrostatic interactions between the guanine group of the Chlorhexidine and the sulfonate group of the dye must be considered in order to explain the adsorption process.

Study of the Duration of Treatment in Drug Prescriptions Received in Pharmacies in Dakar

The prescription must include the name of the drugs or products prescribed, dosage form, dosage, directions for use and duration of treatment. However, sometimes errors can occur that can have consequences for the health of patients. Our study concerns the use of medical prescriptions received in pharmacies in the Dakar department. The survey was conducted in 90 pharmacies in these communes, which represent one third of the 270 pharmacies in the department of Dakar. This allowed us to study 2700 prescriptions. The study took place from 1 December 2016 to 30 June 2017, i.e. over a period of 7 months. Our results show that neurologists and urologists have a longer average treatment time than other specialists, with an average of 120 days and 90 days of treatment respectively. Then, the specialists who take a long time the drug represent more than 27%, and require renewal of the drug. In 63.90% of the cases, no notification on the duration of treatment was given by the prescriber. Only 5.39% were only given the mention “to be renewed”. At the end of our analysis, we can say that the prescription must be perfectly legible to avoid confusion by the patient or the pharmacist. The pharmacist then participates in the therapeutic education of the patient and thus helps him/her to live better with his/her disease. Therefore, socio-professional health associations and organisations must provide more continuous training on prescribing to ensure good compliance and above all avoid people buying medicines in the parallel circuit in order to better control health expenditure.

Oral Healthcare Renunciation and Socioeconomic Determinants

The unequal access to healthcare in general and oral healthcare, in particular, is a true public health concern. Thus, it is important to assess the oral healthcare renunciation and socioeconomic determinants to take appropriate measures. A cross-sectional, descriptive population-based study of 300 households was carried out between April 28, 2016, and May 28, 2016, according to WHO’s guidelines (Protocol 1997), in Senegal adapted form. Results showed that 18.23% of householders report that their household members have foregone oral healthcare. Among those who renounced care, 51.5% did so for care costs (24.2%) or remoteness of health facilities (27.3%) reasons. Therefore, dental treatment renunciation was independently associated to income level, age, sex, marital status, and types of oral healthcare coverage. This study’s analysis shows that oral healthcare renunciation depends primarily on the financial aspect and the remoteness of health structures. Still, there are other important socio-anthropological parameters that should be investigated.

Statistical Evaluation of Anthropometric Measures and Oral Health Status in Terms of Diet, Smoking and Brushing Habits

Introduction and Objective: The aim of this research was to find out the interaction of anthropometric measurements particularly body mass and oral health status of Turkish young adult nationals regionally, depending on the effects of diet (food and fluid consumption), smoking and tooth brushing habits, which were determined by using the body mass index (BMI) and dental health index (DMFT). Material and Methods: The BMI and DMFT of 202 cases, with an age average 22.5 years, were recorded through physical and clinical examinations. Statistical evaluation of the data was checked by Cronbach’s Alpha Reliability Scale and performed by analysis of variance, Somer’s d and Pearson Chi-Square statistics, Poisson Regression and Odds Ratio analysis. Results: The results showed that the mean of BMI was at the optimum level (21.52) for all cases. The DMFT was higher for underweight females and for overweight males. The mean of DMFT according to sexes seemingly had no significant difference;however, females had 8.6% more DMFT than males. When the risk factors of dental caries were evaluated, the DMFT was found as 19.3% more for cases consuming high carbohydrate foods, 4.5% more for high beverage consumption and 18% more for smokers. Conclusions: In conclusion, tooth brushing 3 or more times a day is necessary to decrease the DMFT and tooth brushing 3 times a day as opposed to 1 or 2 times shows significant difference regarding oral health.

Characterization of Pectin Nanocoatings at Polystyrene and Titanium Surfaces

The titanium implant surface plays a crucial role for implant incorporation into bone. A new strategy to improve implant integration in a bone is to develop surface nanocoatings with plant-derived polysaccharides able to increase adhesion of bone cells to the implant surface. The aim of the present study was to physically characterize and compare polystyrene and titanium surfaces nanocoated with different Rhamnogalacturonan-Is (RG-I) and to visualize RG-I nanocoatings. RG-Is from potato and apple were coated on aminated surfaces of polystyrene, titianium discs and titanium implants. To characterize, compare and visualize the surface nanocoatings measurements of contact angle measurements and surface roughness with atomic force microscopy, scanning electron microscopy, and confocal microscopy was performed. We found that, both unmodified and enzymatic modified RG-Is influenced surface wettability, without any major effect on surface roughness (Sa, Sdr). Furthermore, we demonstrated that it is possible to visualize the pectin RG-Is molecules and even the nanocoatings on titanium surfaces, which have not been presented before. The comparison between polystyrene and titanium surface showed that the used material affected the physical properties of non-coated and coated surfaces. RG-Is should be considered as a candidate for new materials as organic nanocoatings for biomaterials in order to improve bone healing.

Age estimation of individuals aged 5-23 years based on dental development of the Indonesian population

Dental development can be used to estimate age for forensic purposes.However,most of the currently available methods are less reliable for the Indonesian population due to population variability.This study presents a new method and evaluates other methods that utilize dental development to estimate the age of Indonesian people.Panoramic radiographs of 304 young Indonesian people aged 5–23 years old were analysed for deciduous tooth root resorption,permanent tooth calcification,and eruption.The extent of tooth root resorption was determined based on AlQahtani’s modified Moorrees et al.method.Tooth calcification was classified based on a modified Demirjian et al.method.Tooth eruption was evaluated based on AlQahtani’s modified Bengston system.The sequence of tooth root resorption,and permanent tooth calcification and eruption were grouped into 19 age categories(from 5–23 years old)in an atlas.The differences between males and females,between maxillary and mandibular teeth,and between right and left teeth were also analysed.There were minimal significant differences of tooth development between males and females,and between the right and left teeth(P>0.05),while the maxillary and mandibular dental development was significantly different(P<0.05).The newly developed atlas showed the development of the right side of maxillary and mandibular tooth of combined sex of Indonesian population.Another 34 panoramic radiographs of known-age and sex individuals from Indonesia were assessed using the newly developed Atlas of Dental Development in the Indonesian Population,Ubelaker’s Dental Development Chart,The London Atlas of Human Tooth Development and Eruption by AlQahtani,and the Age Estimation Guide-Modern Australia population by Blenkin-Taylor.Accuracy was assessed by comparing estimated age to actual chronological age using the Bland-Altmand test.Results show that the smallest range of error was found in the Atlas of Dental Development in the Indonesian Population(−0.969 to 1.210 years),followed by The London Atlas of Human Tooth Development and Eruption by AlQahtani(−2.013 to 1.990 years),the Age Estimation Guide-Modern Australia population by Blenkin-Taylor(−2.495 to 2.598 years),and the Dental Development Chart by Ubelaker(−2.960 to 3.289 years).These findings show that the Atlas of Dental Development constructed in this study performs better than the other three methods and presents greater accuracy of age estimation in the Indonesian population.