This study investigated the vibration frequency in micro-vibration therapy (MVT) performed as a part of nursing care in Japan. We surveyed 31 nurses (25 women and 6 men) who performed MVT with accelerometers attached ...This study investigated the vibration frequency in micro-vibration therapy (MVT) performed as a part of nursing care in Japan. We surveyed 31 nurses (25 women and 6 men) who performed MVT with accelerometers attached to the backs of their hands, and the data obtained were analyzed. The mean vibration frequency was 8.3 Hz (standard deviation [SD]: 1.9 Hz) bilaterally, with a left-right difference of 0.8 Hz (SD: 1.1 Hz, right > left). Furthermore, vibration frequency was correlated with duration of MVT use (rs = 0.5, P < 0.01). The vibration frequency was higher in men (9.2 Hz, SD: 2.4 Hz) than in women (8.1 Hz, SD: 1.8 Hz), but this difference was not significant (P = 0.34). The vibrations of MVT are of a lower frequency than those of other vibration therapies.展开更多
A study the with first principles calculation of the interfaces of the Ni layer or Cu layer on the Fe(100) surface formed with metal plating was performed.Ni or Cu atoms were shown to adopt the corresponding position ...A study the with first principles calculation of the interfaces of the Ni layer or Cu layer on the Fe(100) surface formed with metal plating was performed.Ni or Cu atoms were shown to adopt the corresponding position to the bcc structure of the Fe(100) substrate.Other calculations showed that the interfaces of Ni(5 atomic layers)/Fe(100)(5 layers) or Cu(5 atomic layers)/Fe(100)(5 layers) had square lattices.The orientation relationship of Ni/Fe(100) interface corresponds to fcc-Ni(100)//bcc-Fe(100),Ni[011]//Fe[010],and Ni[011]//Fe[001].Similar results were obtained for Cu/Fe(100) interfaces.This structure was supported by TEM analysis of plated Ni layer on Fe(100) surfaces.The adhesion strength of the Ni/Fe(100) interface evaluated by first principles calculation was higher than that of the Cu/Fe(100) interface.The experimental results of Hull cell iron plated with Ni or Cu supported the results of the calculation.These results indicate that the first principles calculation,which deals with the ideal interface at the atomic scale,has the potential to evaluate the adhesion strength of metallic material interfaces.展开更多
Objectives:To translate and study the factor structure of a Japanese version of the Stressors in Nursing Students scale.Methods:The Stressors in Nursing Students scale was translated into Japanese and administered to ...Objectives:To translate and study the factor structure of a Japanese version of the Stressors in Nursing Students scale.Methods:The Stressors in Nursing Students scale was translated into Japanese and administered to a large cohort(N=1298)of female Japanese nursing students across five universities and across all four years of the nursing programme.The data were analysed using exploratory factor analysis.Results:Exploratory factor analysis revealed four factors:‘Clinical’;‘Conflict and confidence’;‘Education’;and‘Free time’.The relationship between the total score on the Stressors in Nursing Students scale and the demographic aspects of the sample was weak but there was a significant increase in the perception of stressors between first and second year students.Conclusions:There were similarities and differences between the perception of stressors by nursing students in Japan compared with,for example,the United Kingdom and China mainland.While a fourfactor structure was found here,the distribution of items in the Stressors in Nursing Students scale differed from previous studies in the United Kingdom and China with the‘Free time’factor being unique to this study.Stress is an issue for nursing students and is related to the specific stressors they encounter in the process of their work and study.Findings can inform the development of strategies to reduce such stressors among nursing students in multiple,global contexts.展开更多
Today, latent heat storage technology has advanced to allow reuse of waste heat in the middle-temperature range. This paper describes an approach to develop a latent heat storage system using middle-temperature waste ...Today, latent heat storage technology has advanced to allow reuse of waste heat in the middle-temperature range. This paper describes an approach to develop a latent heat storage system using middle-temperature waste heat (~100oC - 200oC) from factories. Direct contact melting and solidification behavior between a heat-transfer fluid (oil) and a latent heat storage material mixture were observed. The mixture consisted of mannitol and erythritol (Cm = 70 mass %, Ce = 30 mass %) as a phase-change material (PCM). The weight of the PCM was 3.0 kg and the flow rate of the oil, foil, was 1.0, 1.5, or 2.0 kg/min. To decrease the solidified height of the PCM mixture during the solidification process, a perforated partition plate was installed in the PCM region in the heat storage vessel. PCM coated oil droplets were broken by the perforated partition plate, preventing the solidified height of the PCM from increasing. The solidification and melting processes were repeated using metal fiber. It was found that installing the metal fiber was more effective than installing the perforated partition plate to prevent the flow out problem of the PCM.展开更多
We screened 15 Agromyces strains from the Microbacteriaceae family and 16 Gordonia strains from the Gordoniaceae family to investigate their biocatalytic ability to reduce carbonyl compounds. Two Agromyces strains (A....We screened 15 Agromyces strains from the Microbacteriaceae family and 16 Gordonia strains from the Gordoniaceae family to investigate their biocatalytic ability to reduce carbonyl compounds. Two Agromyces strains (A. soli NBRC109063 and A. humatus NBRC109085) and two Gordonia strains (G. hydrophobica NBRC16057 and G. malaquae NBRC108250) grew well in 230 medium. The stereoselective reduction of various carbonyl compounds using these four strains was investigated. We discovered that these strains can reduce aliphatic and aromatic α-keto esters and an aromatic α-keto amide. On the basis of the conversion rate and stereoselectivity of the alcohols produced, G. hydrophobica NBRC16057 is a potential biocatalyst for the stereoselective reduction of α-keto esters and an aromatic α-keto amide to the corresponding chiral alcohols. Our results also suggest that the reduction of ethyl 2-methylacetoacetate by wet G. hydrophobica NBRC16057 cells in the presence of L-glutamate is useful for the production of chiral ethyl 3-hydroxy-2-methylbutanoate.展开更多
New ionization and detection techniques in mass spectrometry have been successfully applied for efficient analyses of complex biological systems. It is, however, still difficult to trace structural changes of a specif...New ionization and detection techniques in mass spectrometry have been successfully applied for efficient analyses of complex biological systems. It is, however, still difficult to trace structural changes of a specific molecular species in such systems. In the present study, a molecular probe strategy in combination with tandem electrospray ionization mass spectrometry has been examined using synthetic deuterium-labeled phosphatidylcholine hydroperoxide (PC-OOH/D3) and ethyl-labeled phosphatidylcholine having docosahexaenoic acid side chain (DHA-PC/Et). Administration of a mixture of PC-OOH/D3 and DHA-PC/Et to human blood and human skin surface, followed by extraction and analysis with collision-induced tandem electrospray ionization mass spectrometry demonstrated that metabolites of both molecular probes can be detected simultaneously with strict selectivity. The present method is also found to be useful in tracing chemical changes of the unstable docosahexaenoyl group on the surface of processed fish. The activity of phospholipase A2 can also be assessed using a phospholipid molecular probe with a linoleoyl and a deuteriomethyl group via selective detection of the lyso-phospholipid product by mass spectrometry. The advantage of the present method is that no chromatographic separation is required and analysis can be performed under strictly the same condition for different molecular probes, affording multiple data by one experiment. The present strategy may be useful for tracing time-dependent phenomena in dynamic phospholipid biochemistry, and can be widely used for any biological and food systems.展开更多
To research the potential ability of marine-derived actinomycetes to act as biocatalysts, 8 Micromonospora strains and 5 Streptomyces strains were screened. Two recommended media (227 and 1076 media) and 2 modified me...To research the potential ability of marine-derived actinomycetes to act as biocatalysts, 8 Micromonospora strains and 5 Streptomyces strains were screened. Two recommended media (227 and 1076 media) and 2 modified media (1076-25% and P-1076-25% media) for liquid culture of these marine-derived actinomycetes were tested. As a result, 2 Micromonospora strains (Micromonospora sp. NBRC107096 and 107097) cultured with the 1076-25% medium and 2 Streptomyces strains (Streptomyces tateyamensis NBRC105048 and Streptomyces sp. NBRC105896) cultured with P-1076-25% medium showed a good growth. The stereoselective reduction of α-keto esters using these 4 actinomycetes was tested. As a result, it was found that these strains had a reducing activity toward various α-keto esters. The introduction of L-glutamate or sucrose as an additive remarkably increased the conversion ratios in the reduction of substrates by the Micromonospora strain. Furthermore, in the presence of L-alanine, Streptomyces tateyamensis NBRC105048 reduced ethyl pyruvate, ethyl 2-oxobutanoate, ethyl 2-oxopentanoate, ethyl 2-oxohexanoate, and ethyl 3-methyl-2-oxobutyrate to the corresponding α-hydroxy ester with a high conversion ratio and with excellent enantiomeric excess. Thus, we found that these marine-derived actinomycetes have great potential to be used as biocatalysts for stereoselective reduction of carbonyl compounds.展开更多
A flexible supporting structure that reduces seismic response of an arch is proposed. Topology and cross-sectional areas of the supporting structure modeled as a truss structure are optimized through two steps of stat...A flexible supporting structure that reduces seismic response of an arch is proposed. Topology and cross-sectional areas of the supporting structure modeled as a truss structure are optimized through two steps of static and dynamic optimization problems. In the first step, a flexible supporting structure that has diagonal displacement at the top under horizontal load is obtained by solving static optimization problems. Then, in the second step, the cross-sectional area of the flexible member is optimized to minimize the seismic response acceleration of the arch evaluated by the complete quadratic combination(CQC) method. Time-history seismic response analysis is carried out to show that the response in the normal direction of the roof successfully decreases due to flexibility of the supporting structure; in addition, installing passive energy dissipation devices into the flexible supporting structure is very effective in reducing the tangential response of the arch.展开更多
We shall introduce a new geometric constant A(X) of a Banach space X,which is closely related to the modulus of smoothness ρX(τ),and investigate it in relation with the constant A2(X) by Baronti et al.,the von Neum...We shall introduce a new geometric constant A(X) of a Banach space X,which is closely related to the modulus of smoothness ρX(τ),and investigate it in relation with the constant A2(X) by Baronti et al.,the von Neumann–Jordan constant CNJ(X) and the James constant J(X).A sequence of recent results on these constants as well as some other geometric constants will be strengthened and improved.展开更多
A dispersion system fluid can convect even if the dispersoid is a solid phase.Therefore,heat exchange performance can be improved while maintaining fluidity using a material with high thermal conductivity as the dispe...A dispersion system fluid can convect even if the dispersoid is a solid phase.Therefore,heat exchange performance can be improved while maintaining fluidity using a material with high thermal conductivity as the dispersoid.This study presents the melting performance evaluation results of a latent heat storage material with a carbon nanotube(CNT)dispersion system with high thermal conductivity,which enhances the thermal conductivity of the latent heat storage material and does not limit free convection.Increasing the thermal conductivity and enhancing the melting convection of the heat storage material result in increased latent heat storage speed.In this study,the thermal conductivity of the latent heat storage material was successfully increased by dispersing CNTs in the material.When 0.1%(in mass)of multi-wall CNT(MWCNT)was dispersed in a paraffin-based latent heat storage material,the shear stress increased by 1.5 times at a shear rate of 500 s^(-1),while taking into account the potential effects of convective inhibition.Therefore,a latent heat storage experiment was conducted in a rectangular heat storage tank using the CNT dispersion composition ratio as a parameter.A rectangular vessel with a heated vertical surface was used for the latent heat storage experiment.The melting speed was determined by comparing the amount of latent heat stored in a CNT-dispersed latent heat storage material and a single-phase latent heat storage material sample.The experimental results show that the time required for the latent heat storage material to completely melt in the heat storage tank was the shortest for the single-phase latent heat storage material sample.However,the fastest melting progress was observed for the sample with 0.02%(in mass)MWCNT content in the melting rate range of up to approximately 40%in the tank.The results indicate that this phenomenon is caused by the difference in the melting rates in the upper part of the tank.The generated data are useful for determining the shape and heat transfer surface arrangement of the latent heat storage tank.展开更多
文摘This study investigated the vibration frequency in micro-vibration therapy (MVT) performed as a part of nursing care in Japan. We surveyed 31 nurses (25 women and 6 men) who performed MVT with accelerometers attached to the backs of their hands, and the data obtained were analyzed. The mean vibration frequency was 8.3 Hz (standard deviation [SD]: 1.9 Hz) bilaterally, with a left-right difference of 0.8 Hz (SD: 1.1 Hz, right > left). Furthermore, vibration frequency was correlated with duration of MVT use (rs = 0.5, P < 0.01). The vibration frequency was higher in men (9.2 Hz, SD: 2.4 Hz) than in women (8.1 Hz, SD: 1.8 Hz), but this difference was not significant (P = 0.34). The vibrations of MVT are of a lower frequency than those of other vibration therapies.
文摘A study the with first principles calculation of the interfaces of the Ni layer or Cu layer on the Fe(100) surface formed with metal plating was performed.Ni or Cu atoms were shown to adopt the corresponding position to the bcc structure of the Fe(100) substrate.Other calculations showed that the interfaces of Ni(5 atomic layers)/Fe(100)(5 layers) or Cu(5 atomic layers)/Fe(100)(5 layers) had square lattices.The orientation relationship of Ni/Fe(100) interface corresponds to fcc-Ni(100)//bcc-Fe(100),Ni[011]//Fe[010],and Ni[011]//Fe[001].Similar results were obtained for Cu/Fe(100) interfaces.This structure was supported by TEM analysis of plated Ni layer on Fe(100) surfaces.The adhesion strength of the Ni/Fe(100) interface evaluated by first principles calculation was higher than that of the Cu/Fe(100) interface.The experimental results of Hull cell iron plated with Ni or Cu supported the results of the calculation.These results indicate that the first principles calculation,which deals with the ideal interface at the atomic scale,has the potential to evaluate the adhesion strength of metallic material interfaces.
文摘Objectives:To translate and study the factor structure of a Japanese version of the Stressors in Nursing Students scale.Methods:The Stressors in Nursing Students scale was translated into Japanese and administered to a large cohort(N=1298)of female Japanese nursing students across five universities and across all four years of the nursing programme.The data were analysed using exploratory factor analysis.Results:Exploratory factor analysis revealed four factors:‘Clinical’;‘Conflict and confidence’;‘Education’;and‘Free time’.The relationship between the total score on the Stressors in Nursing Students scale and the demographic aspects of the sample was weak but there was a significant increase in the perception of stressors between first and second year students.Conclusions:There were similarities and differences between the perception of stressors by nursing students in Japan compared with,for example,the United Kingdom and China mainland.While a fourfactor structure was found here,the distribution of items in the Stressors in Nursing Students scale differed from previous studies in the United Kingdom and China with the‘Free time’factor being unique to this study.Stress is an issue for nursing students and is related to the specific stressors they encounter in the process of their work and study.Findings can inform the development of strategies to reduce such stressors among nursing students in multiple,global contexts.
文摘Today, latent heat storage technology has advanced to allow reuse of waste heat in the middle-temperature range. This paper describes an approach to develop a latent heat storage system using middle-temperature waste heat (~100oC - 200oC) from factories. Direct contact melting and solidification behavior between a heat-transfer fluid (oil) and a latent heat storage material mixture were observed. The mixture consisted of mannitol and erythritol (Cm = 70 mass %, Ce = 30 mass %) as a phase-change material (PCM). The weight of the PCM was 3.0 kg and the flow rate of the oil, foil, was 1.0, 1.5, or 2.0 kg/min. To decrease the solidified height of the PCM mixture during the solidification process, a perforated partition plate was installed in the PCM region in the heat storage vessel. PCM coated oil droplets were broken by the perforated partition plate, preventing the solidified height of the PCM from increasing. The solidification and melting processes were repeated using metal fiber. It was found that installing the metal fiber was more effective than installing the perforated partition plate to prevent the flow out problem of the PCM.
文摘We screened 15 Agromyces strains from the Microbacteriaceae family and 16 Gordonia strains from the Gordoniaceae family to investigate their biocatalytic ability to reduce carbonyl compounds. Two Agromyces strains (A. soli NBRC109063 and A. humatus NBRC109085) and two Gordonia strains (G. hydrophobica NBRC16057 and G. malaquae NBRC108250) grew well in 230 medium. The stereoselective reduction of various carbonyl compounds using these four strains was investigated. We discovered that these strains can reduce aliphatic and aromatic α-keto esters and an aromatic α-keto amide. On the basis of the conversion rate and stereoselectivity of the alcohols produced, G. hydrophobica NBRC16057 is a potential biocatalyst for the stereoselective reduction of α-keto esters and an aromatic α-keto amide to the corresponding chiral alcohols. Our results also suggest that the reduction of ethyl 2-methylacetoacetate by wet G. hydrophobica NBRC16057 cells in the presence of L-glutamate is useful for the production of chiral ethyl 3-hydroxy-2-methylbutanoate.
文摘New ionization and detection techniques in mass spectrometry have been successfully applied for efficient analyses of complex biological systems. It is, however, still difficult to trace structural changes of a specific molecular species in such systems. In the present study, a molecular probe strategy in combination with tandem electrospray ionization mass spectrometry has been examined using synthetic deuterium-labeled phosphatidylcholine hydroperoxide (PC-OOH/D3) and ethyl-labeled phosphatidylcholine having docosahexaenoic acid side chain (DHA-PC/Et). Administration of a mixture of PC-OOH/D3 and DHA-PC/Et to human blood and human skin surface, followed by extraction and analysis with collision-induced tandem electrospray ionization mass spectrometry demonstrated that metabolites of both molecular probes can be detected simultaneously with strict selectivity. The present method is also found to be useful in tracing chemical changes of the unstable docosahexaenoyl group on the surface of processed fish. The activity of phospholipase A2 can also be assessed using a phospholipid molecular probe with a linoleoyl and a deuteriomethyl group via selective detection of the lyso-phospholipid product by mass spectrometry. The advantage of the present method is that no chromatographic separation is required and analysis can be performed under strictly the same condition for different molecular probes, affording multiple data by one experiment. The present strategy may be useful for tracing time-dependent phenomena in dynamic phospholipid biochemistry, and can be widely used for any biological and food systems.
文摘To research the potential ability of marine-derived actinomycetes to act as biocatalysts, 8 Micromonospora strains and 5 Streptomyces strains were screened. Two recommended media (227 and 1076 media) and 2 modified media (1076-25% and P-1076-25% media) for liquid culture of these marine-derived actinomycetes were tested. As a result, 2 Micromonospora strains (Micromonospora sp. NBRC107096 and 107097) cultured with the 1076-25% medium and 2 Streptomyces strains (Streptomyces tateyamensis NBRC105048 and Streptomyces sp. NBRC105896) cultured with P-1076-25% medium showed a good growth. The stereoselective reduction of α-keto esters using these 4 actinomycetes was tested. As a result, it was found that these strains had a reducing activity toward various α-keto esters. The introduction of L-glutamate or sucrose as an additive remarkably increased the conversion ratios in the reduction of substrates by the Micromonospora strain. Furthermore, in the presence of L-alanine, Streptomyces tateyamensis NBRC105048 reduced ethyl pyruvate, ethyl 2-oxobutanoate, ethyl 2-oxopentanoate, ethyl 2-oxohexanoate, and ethyl 3-methyl-2-oxobutyrate to the corresponding α-hydroxy ester with a high conversion ratio and with excellent enantiomeric excess. Thus, we found that these marine-derived actinomycetes have great potential to be used as biocatalysts for stereoselective reduction of carbonyl compounds.
文摘A flexible supporting structure that reduces seismic response of an arch is proposed. Topology and cross-sectional areas of the supporting structure modeled as a truss structure are optimized through two steps of static and dynamic optimization problems. In the first step, a flexible supporting structure that has diagonal displacement at the top under horizontal load is obtained by solving static optimization problems. Then, in the second step, the cross-sectional area of the flexible member is optimized to minimize the seismic response acceleration of the arch evaluated by the complete quadratic combination(CQC) method. Time-history seismic response analysis is carried out to show that the response in the normal direction of the roof successfully decreases due to flexibility of the supporting structure; in addition, installing passive energy dissipation devices into the flexible supporting structure is very effective in reducing the tangential response of the arch.
基金The second author is supported in part by Grant-in-Aid for Scientific Research,Japan Society for the Promotionof Science(Grant No.23540216)
文摘We shall introduce a new geometric constant A(X) of a Banach space X,which is closely related to the modulus of smoothness ρX(τ),and investigate it in relation with the constant A2(X) by Baronti et al.,the von Neumann–Jordan constant CNJ(X) and the James constant J(X).A sequence of recent results on these constants as well as some other geometric constants will be strengthened and improved.
基金supported by JSPS KAKENHI(Grant numbers JP18K03999 and 22K03958)。
文摘A dispersion system fluid can convect even if the dispersoid is a solid phase.Therefore,heat exchange performance can be improved while maintaining fluidity using a material with high thermal conductivity as the dispersoid.This study presents the melting performance evaluation results of a latent heat storage material with a carbon nanotube(CNT)dispersion system with high thermal conductivity,which enhances the thermal conductivity of the latent heat storage material and does not limit free convection.Increasing the thermal conductivity and enhancing the melting convection of the heat storage material result in increased latent heat storage speed.In this study,the thermal conductivity of the latent heat storage material was successfully increased by dispersing CNTs in the material.When 0.1%(in mass)of multi-wall CNT(MWCNT)was dispersed in a paraffin-based latent heat storage material,the shear stress increased by 1.5 times at a shear rate of 500 s^(-1),while taking into account the potential effects of convective inhibition.Therefore,a latent heat storage experiment was conducted in a rectangular heat storage tank using the CNT dispersion composition ratio as a parameter.A rectangular vessel with a heated vertical surface was used for the latent heat storage experiment.The melting speed was determined by comparing the amount of latent heat stored in a CNT-dispersed latent heat storage material and a single-phase latent heat storage material sample.The experimental results show that the time required for the latent heat storage material to completely melt in the heat storage tank was the shortest for the single-phase latent heat storage material sample.However,the fastest melting progress was observed for the sample with 0.02%(in mass)MWCNT content in the melting rate range of up to approximately 40%in the tank.The results indicate that this phenomenon is caused by the difference in the melting rates in the upper part of the tank.The generated data are useful for determining the shape and heat transfer surface arrangement of the latent heat storage tank.
