Effects of Seasonal and Temperature Variations on the Association between Nitrogen Dioxide Exposure and First-Aid Incidence for Neurological Diseases in Shenzhen,China

Neurological disorders,including headaches(tension-type headaches,medication-overuse headaches,and migraines)and dementias that include Alzheimer’s disease,are among the most prevalent and debilitating global conditions.In 2016,these disorders affected 276 million people worldwide and were the second leading cause of death that year[1].This highlights the urgent need for effective prevention,treatment,and support strategies.The etiology of neurological disorders is multifaceted and involves genetic,environmental,physiological,and social factors[2].

Insight into Financial Support for Rural Land Circulation:A Case Study of China Taiwan

Based on the background of the second rural land reform in China Taiwan, we analyzed financial support measures and their effects. It comes to the insight into financial support for rural land circulation in China Taiwan for the new round of rural land reform in China mainland. It is proposed to: (i) put forth effort on rural infrastructure construction with financial special fund as major support and credit fund from policy bank as supplementary support; (ii) improve rural land evaluation, registration and guarantee systems and set up special loan for land circulation, to solve the problem of shortage of fund for farmers purchasing land; (iii) grant operating loans for rural large planting and breeding farmer households, to accelerate land circulation becoming effective; (iv) establish development fund for agriculture, farmers and rural areas, to ensure sustainable input into rural areas.

Managing Dynamics in Corporate Networks

A crucial issue in collaborating in manufacturing corporate networks between different companies is to identify to what extent different strategic and operational decisions need to be coordinated between the involved companies. In this paper, we elaborate on the issue of synchronization and coordination of information flow based on interconnectivities between companies in order to coordinate a corporate network by the means of DSM, Dependence Structure Matrix. The results show that DSM can be used to identify interconnectivities, dependencies on information flow among actors in a network and to identify which information needs to be shared between companies in the network.

Development Status and Prospects of Chinese Natural Gas Industry in 2021

China’s natural gas industry saw a strong rebound in supply and demand in 2021,with apparent consumption reaching 372.6 billion m^(3),up by 12.7%year on year.The increase in domestic gas reserves and production continued to advance,with production reaching 208.6 billion m^(3),an increase of more than 10 billion m^(3) for five consecutive years.Imported natural gas grew at a high rate,with imported pipeline gas and imported LNG totaling 169.1 billion m^(3) in 2021,up by 20.9%year on year,making China the world’s top LNG importer for the first time.In 2022,as China’s economy continues to recover steadily and the development of clean energy decarbonization continues under the“Carbon Peaking and Carbon Neutrality Goals”strategy,the natural gas market will maintain sustained growth,but the incremental demand level and growth rate will be lower than in 2021,with demand growth expected to reach 6%-7%.

Differences in the system accuracy acceptability of four types of blood glucose monitoring systems against five different standards

Objective:This study aimed to evaluate the system accuracy of four types of blood glucose monitoring systems(BGMSs)and explore the differences in the system accuracy acceptability of each BGMS against five different standards.Methods:The glucose measurement values obtained from four types of BGMSs(Roche Accu-Chek® Performa,Bayer Contour™ TS,Sinomedisite Glupad® H1 Plus,and Sinocare® Gold-Accu)were evaluated against the reference values obtained from the biochemical analyzer of the central laboratory.The system accuracy acceptability of each BGMS was determined using the criteria specified in five standards,namely the International Organization for Standardization(ISO)15197:2003,Clinical Laboratory Standards Institute(CLSI)POCT12-A3,ISO 15197:2013,Chinese Society of Laboratory Medicine(CSLM)consensus,and US Food and Drug Administration(FDA)guidelines.Results:From 2018 to 2022,10,980 pairs of measurement values were obtained from 366 glucose meters of four types of BGMSs.Significant correlations were observed between the glucose measurement values from the BGMSs and the reference values from the biochemical analyzer of the central laboratory.The correlation coefficient r was 0.995 for Roche Accu-Chek® Performa,0.994 for Bayer Contour™ TS,0.983 for Sinomedisite Glupad® H1 Plus,and 0.997 for SinocareR Gold-Accu.The acceptability criteria specified in ISO 15197:2003 were met by 100.00%(135/135)of the glucose meters of Roche Accu-Chek® Performa,100.00%(109/109)of Bayer Contour™ TS,81.61%(71/87)of Sinomedisite Glupad® H1 Plus,and 100.00%(35/35)of SinocareR Gold-Accu.Whereas,the acceptability criteria specified in ISO 15197:2013 were met by 99.26%(134/135)of the glucose meters of Roche Accu-Chek® Performa,88.07%(96/109)of Bayer Contour™ TS,58.62%(51/87)of Sinomedisite Glupad R H1 Plus,and 91.43%(32/35)of SinocareR Gold-Accu.Conclusions:Among the four types of BGMSs evaluated,the glucose meters of Roche Accu-Chek® Performa exhibited superior system accuracy.The system accuracy acceptability of each BGMS varied significantly against the acceptability criteria specified in the five different standards.

Accuracy evaluation of Roche Accu-Chek Performa blood glucose meters at low glucose concentrations:A nine-year retrospective study

Objective:To evaluate the accuracy of Roche Accu-Chek Performa glucose meters at a low glucose concentration of<5.55 mmol/L(100 mg/dL)over a 9-year period.Methods:The accuracy of the Roche Accu-Chek Performa glucose meters at low glucose concentrations was evaluated using annual comparison data for 9 consecutive years from 2015 to 2023,according to the acceptability criteria specified in International Organization for Standardization(ISO)15197:2013.Blood samples with low glucose concentrations of<5.55 mmol/L were prepared by incubation and glycolysis.The glucose concentration was detected using Roche Accu-Chek Performa glucose meters and a biochemical analyzer in the central laboratory.Results:A total of 2978 pairs of comparison results from 211 glucose meters at a low glucose concentration of<5.55 mmol/L were retrospectively analyzed from 2015 to 2023.The clinical use duration spanned from 1 to 9 years and 40.76%(86 out of 211 glucose meters)had been used for more than 2 years.The correlation coefficient r between glucose meter measurements and laboratory reference values was 0.98(p<0.001).The mean according to Roche Accu-Chek Performa glucose meters was 0.05 mmol/L(0.9 mg/dL)higher than that of the biochemical analyzer(Z=-13.82,p<0.0001).The results showed that 100.00%(211 out of 211)of the Roche Accu-Chek Performa glucose meters met the acceptability criteria specified in ISO 15197:2013.At a low glucose concentration of<5.55 mmol/L,99.90%(2975 out of 2978)of the comparative data pairs in the error distribution fell within the range of±0.83 mmol/L(15 mg/dL).Parkes consensus error grid analysis showed that 100.00%(2978 out of 2978)of comparative data pairs fell within region A.Conclusions:This study demonstrated that Roche Accu-Chek Performa glucose meters successfully met the accuracy standards of ISO 15197:2013 for measuring blood glucose within the hypoglycemic range.Greater attention should be given to the performance of blood glucose monitoring systems in the low glycemic range,especially for patients with diabetes who are prone to hypoglycemia and require precise measurements.

A HYBRID APPROACH FOR MINIMIZING MAKESPAN IN PERMUTATION FLOWSHOP SCHEDULING

This work proposes a hybrid approach for solving traditional flowshop scheduling problems to reduce the makespan （total completion time）. To solve scheduling problems, a combination of Decision Tree （DT） and Scatter Search （SS） algorithms are used. Initially, the DT is used to generate a seed solution which is then given input to the SS to obtain optimal / near optimal solutions of makespan. The DT used the entropy function to convert the given problem into a tree structured format / set of rules. The SS provides an extensive investigation of the search space through diversification. The advantages of both DT and SS are used to form a hybrid approach. The proposed algorithm is tested with various benchmark datasets available for flowshop scheduling. The statistical results prove that the proposed method is competent and efficient for solving flowshop problems.

Optimal periodic replacement policy for a warranted product subject to multi modes failure process

A complex product subjects to multiple failure modes such as minor and catastrophic failure with some probability.This paper investigates the effects of minor failure and catastrophic failure on the periodic replacement policy for a complex product supported by a warranty period.Cost models are developed and the expected optimal replacement policies are developed analytically such that long run expected life-cycle cost rate is minimized.Structural properties of the optimal replacement policies are derived for a product which fails with multiple failure modes and the failure rate is an increasing function of time.Finally,a numerical experiment is performed to show the important features of our study.