BACKGROUND Emerging infectious diseases are a constant threat to the public’s health and health care systems around the world.Coronavirus disease 2019(COVID-2019),which was defined by the World Health Organization as...BACKGROUND Emerging infectious diseases are a constant threat to the public’s health and health care systems around the world.Coronavirus disease 2019(COVID-2019),which was defined by the World Health Organization as pandemic,has rapidly emerged as a global health threat.Outbreak evolution and prevention of international implications require substantial flexibility of frontline health care facilities in their response.AIM To explore the effect of the implementation and management strategy of prescreening triage in children during COVID-19.METHODS The standardized triage screening procedures included a standardized triage screening questionnaire,setup of pre-screening triage station,multi-point temperature monitoring,extensive screenings,and two-way protection.In order to ensure the implementation of the pre-screening triage,the prevention and control management strategies included training,emergency exercise,and staff protection.Statistical analysis was performed on the data from all the children hospitalized from January 20,2020 to March 20,2020 at solstice during the pandemic period.Data were obtained from questionnaires and electronic medical record systems.RESULTS A total of 17561 children,including 2652 who met the criteria for screening,192 suspected cases,and two confirmed cases without omission,were screened from January 20,2020 to March 20,2020 at solstice during the pandemic period.There was zero transmission of the infection to any medical staff.CONCLUSION The effective strategies for pre-screening triage have an essential role in the prevention and control of hospital infection.展开更多
Background:The levels of ghrelin and tumor necrosis factor alpha (TNF-a) are considered biological markers of congenital heart diseases (CHD).The present meta-analysis was conducted to investigate the clinical signifi...Background:The levels of ghrelin and tumor necrosis factor alpha (TNF-a) are considered biological markers of congenital heart diseases (CHD).The present meta-analysis was conducted to investigate the clinical significance of serum levels of ghrelin and TNF-α in children with (CHD).Methods:Chinese and English scientific literature databases were searched to retrieve published studies relevant to ghrelin,TNF-α and CHD.Manual search was additionally employed to identify other relevant studies from cross-references.The retrieved studies were screened on the basis of our stringent inclusion and exclusion criteria to select high quality case-control studies for meta-analysis.Results:We initially retrieved 108 published studies (20 in Chinese and 88 in English) from database searches.Finally,6 case-control studies (5 in English and 1 in Chinese) were enrolled in our meta-analysis,and contained a total of 160 cyanotic congenital heart disease (CCHD) patients and 215 acyanotic congenital heart disease (ACHD) patients,along with 162 healthy controls.The results of meta-analysis showed that serum levels of ghrelin and TNF-α in CCHD or ACHD children were significantly higher than those in healthy controls.Conclusion:Our meta-analysis results showed that serum levels of ghrelin and TNF-α are elevated in children with CHD,and could be used as effective biologic markers in early diagnosis of CHD.展开更多
文摘BACKGROUND Emerging infectious diseases are a constant threat to the public’s health and health care systems around the world.Coronavirus disease 2019(COVID-2019),which was defined by the World Health Organization as pandemic,has rapidly emerged as a global health threat.Outbreak evolution and prevention of international implications require substantial flexibility of frontline health care facilities in their response.AIM To explore the effect of the implementation and management strategy of prescreening triage in children during COVID-19.METHODS The standardized triage screening procedures included a standardized triage screening questionnaire,setup of pre-screening triage station,multi-point temperature monitoring,extensive screenings,and two-way protection.In order to ensure the implementation of the pre-screening triage,the prevention and control management strategies included training,emergency exercise,and staff protection.Statistical analysis was performed on the data from all the children hospitalized from January 20,2020 to March 20,2020 at solstice during the pandemic period.Data were obtained from questionnaires and electronic medical record systems.RESULTS A total of 17561 children,including 2652 who met the criteria for screening,192 suspected cases,and two confirmed cases without omission,were screened from January 20,2020 to March 20,2020 at solstice during the pandemic period.There was zero transmission of the infection to any medical staff.CONCLUSION The effective strategies for pre-screening triage have an essential role in the prevention and control of hospital infection.
文摘Background:The levels of ghrelin and tumor necrosis factor alpha (TNF-a) are considered biological markers of congenital heart diseases (CHD).The present meta-analysis was conducted to investigate the clinical significance of serum levels of ghrelin and TNF-α in children with (CHD).Methods:Chinese and English scientific literature databases were searched to retrieve published studies relevant to ghrelin,TNF-α and CHD.Manual search was additionally employed to identify other relevant studies from cross-references.The retrieved studies were screened on the basis of our stringent inclusion and exclusion criteria to select high quality case-control studies for meta-analysis.Results:We initially retrieved 108 published studies (20 in Chinese and 88 in English) from database searches.Finally,6 case-control studies (5 in English and 1 in Chinese) were enrolled in our meta-analysis,and contained a total of 160 cyanotic congenital heart disease (CCHD) patients and 215 acyanotic congenital heart disease (ACHD) patients,along with 162 healthy controls.The results of meta-analysis showed that serum levels of ghrelin and TNF-α in CCHD or ACHD children were significantly higher than those in healthy controls.Conclusion:Our meta-analysis results showed that serum levels of ghrelin and TNF-α are elevated in children with CHD,and could be used as effective biologic markers in early diagnosis of CHD.
