期刊文献+
共找到2篇文章
< 1 >
每页显示 20 50 100
Pulmonary capillary hemangiomatosis or hepatopulmonary syndrome in a patient with calcinosis,Raynaud’s phenomenon,esophageal dysmotility,sclerodactyly and telangiectasia syndrome?
1
作者 Bijaya Laxmi Shrestha Ying-Kang Jin 《Chinese Medical Journal》 SCIE CAS CSCD 2020年第2期243-244,共2页
To the Editor:We were interested in the article,which reported a woman with calcinosis,Raynaud’s phenomenon,esophageal dysmotility,sclerodactyly and telangiectasia(CREST)syndrome who developed progressive dyspnea on ... To the Editor:We were interested in the article,which reported a woman with calcinosis,Raynaud’s phenomenon,esophageal dysmotility,sclerodactyly and telangiectasia(CREST)syndrome who developed progressive dyspnea on exertion and was later diagnosed with pulmonary capillary hemangiomatosis(PCH)that was confirmed by an open lung biopsy.[1]We would like to remark that the diagnosis of PCH is inconclusive from just history,treatment,and histological changes.This case also does not specify a clear connection between PCH and CREST syndrome;therefore,we believe we need to explore another possible disease association. 展开更多
关键词 ESOPHAGEAL MOTILITY diagnosis
原文传递
Successful clearance of persistent SARS-CoV-2 asymptomatic infection following a single dose of Ad5-nCoV vaccine 被引量:1
2
作者 Shaofu Qiu Zhao Chen +21 位作者 Airu Zhu Qiuhui Zeng Hongbo Liu Xiaoqing Liu Feng Ye Yingkang Jin Jie Wu Chaojie Yang Qi Wang Fangli Chen Lan Chen Sai Tian Xinying Du Qingtao Hu Jinling Cheng Canjie Chen Fang Li Jing Sun Yanqun Wang Jingxian Zhao Jincun Zhao Hongbin Song 《Signal Transduction and Targeted Therapy》 SCIE CSCD 2023年第4期1942-1952,共11页
Persistent asymptomatic(PA)SARS-CoV-2 infections have been identified.The immune responses in these patients are unclear,and the development of effective treatments for these patients is needed.Here,we report a cohort... Persistent asymptomatic(PA)SARS-CoV-2 infections have been identified.The immune responses in these patients are unclear,and the development of effective treatments for these patients is needed.Here,we report a cohort of 23 PA cases carrying viral RNA for up to 191 days.PA cases displayed low levels of inflammatory and interferon response,weak antibody response,diminished circulating follicular helper T cells(cTfh),and inadequate specific CD4+and CD8+T-cell responses during infection,which is distinct from symptomatic infections and resembling impaired immune activation.Administration of a single dose of Ad5-nCoV vaccine to 10 of these PA cases elicited rapid and robust antibody responses as well as coordinated B-cell and cTfh responses,resulting in successful viral clearance.Vaccine-induced antibodies were able to neutralize various variants of concern and persisted for over 6 months,indicating long-term protection.Therefore,our study provides an insight into the immune status of PA infections and highlights vaccination as a potential treatment for prolonged SARS-CoV-2 infections. 展开更多
关键词 infection IMPAIRED ASYMPTOMATIC
原文传递
上一页 1 下一页 到第
使用帮助 返回顶部