Health care staffs’ perception of patient safety culture in hospital settings and factors of importance for this

Many hospital patients are affected by adverse events. Managers are important when improving safety. The perception of patient safety culture varies among health care staff. Health care staff (n = 1023) working in medical, surgical or mixed medical-surgical health care divisions answered the 51 items (14 dimensions) Swedish Hospital Survey on Patient Safety Culture (S-HSOPSC). Respondents with a managerial function scored higher than non-managers for 11 of 14 dimensions, indicating patient safety culture strengths for a majority of dimensions. Enrolled nurses and staff with experience > 10 years also scored high for several dimensions. The 12 dimensions and sample characteristics explained 49% and 26% of the variance for the outcome dimensions Overall Perceptions of Safety and Frequency of Incident Reporting, respectively. RNs, ENs and physicians have different views on patient safety culture. Hospital Management Support and Organisational Learning is some important factors influencing patient safety culture. Bridging the gap in health care staff’s perceptions of safety in order to improve patient safety is of utmost importance. Managers have the responsibility to foster patient safety culture at their workplace and can thus benefit from results when improving safety for patients.

Swedish Hospital Survey on Patient Safety Culture— Psychometric properties and health care staff’s perception

This study examined the psychometric properties of the Swedish and the original version of the Hospital Survey on Patient Safety Culture within a Swedish hospital setting and described health care staff’s perceptions of patient safety culture. A web-survey was used to obtain data from registered nurses, enrolled nurses and physicians (N = 1023). Psychometric properties were tested using Confirmatory Factor Analysis and internal consistency using Cronbach’s alpha coefficient. Root mean square error of approximation and other fit indices indicated psychoFmetric properties for both versions to be acceptable. Internal consistency for the dimensions varied between 0.60 and 0.87. Staff scored the dimension “Teamwork Within Units” highest and the dimension “Hospital Management Support” the lowest. The safety was graded as very good or excellent by 58.9% of the respondents and one third had reported more than one event in the past 12 months. The questionnaire is considered to be useful for measuring patient safety culture in Swedish hospital settings. Managers have a great responsibility to work with improving patient safety culture.

Healthcare delivery interventions to reduce cancer disparities worldwide

Globally,cancer care delivery is marked by inequalities,where some economic,demographic,and sociocultural groups have worse outcomes than others.In this review,we sought to identify patient-facing interventions designed to reduce disparities in cancer care in both high-and low-income countries.We found two broad categories of interventions that have been studied in the current literature:Patient navigation and telehealth.Navigation has the strongest evidence base for reducing disparities,primarily in cancer screening.Improved outcomes with navigation interventions have been seen in both high-and low-income countries.Telehealth interventions remain an active area of exploration,primarily in high income countries,with the best evidence being for the remote delivery of palliative care.Ongoing research is needed to identify the most efficacious,costeffective,and scalable interventions to reduce barriers to the receipt of cancer care globally.

Exploring the Implementation of Individual Care Plans in Relation to Characteristics of Staff

The aim was to explore the implementation of individual care plans in municipal elderly care in relation to characteristics of staff. Data regarding characteristics of staff were derived through a questionnaire distributed to all staff working in the care for older people, (N = 908, n = 245) in four municipalities in Sweden. The number of care plans established during a one-year period was collected through a contact person in each municipality. In total 47 individual care plans were established during the study year. Significantly more staff in the municipality that had the most number of established individual care plans agreed that there had been sufficient education (p = 0.017), sufficient time (p = 0.002) and routines established regarding individual care plans (p = 0.014) and had a significantly better job satisfaction (p = 0.001), compared to staff in the other municipalities. Implementation leaders may need to take the working conditions and the perception of available resources among staff into consideration in the on-going process of implementing individual care plans.

Burden of malignant mesothelioma in China during 1990-2019 and the projections through 2029

Objective:To provide the most up-to-date data on the burden of malignant mesothelioma(MM)and the projections through 2029 in China.Methods:Data on patients diagnosed with MM from China during 1990-2019 were obtained from the Global Burden of Disease(GBD)2019 database,including annual cases and deaths data and age-standardized rates of incidence,mortality,and disability-adjusted life-years(DALYs)associated with MM among different age groups.Temporal trends during 1990-2019 were analyzed by the Joinpoint regression models using 95%confidence interval(CI),while the projections through 2029 were calculated by the Bayesian age-period-cohort model.Data on the production and consumption of asbestos in China were obtained from the United States Geological Survey on Mineral Commodity Summaries during 1996-2023.Results:We observed a significant elevation in incident new cases and deaths over the last 3 decades,increasing from 1193 in 1990 to 2815 in 2019 for incident cases and from 1134 in 1990 to 2773 in 2019 for death cases.We found a roughly 6%increase in the proportion of incident cases for those aged>70 years(30%in 2019 versus 24%in 1990),while for the proportion of deaths similar elevation for those aged>70 years was found.Additionally,men had significantly higher DALYs due to MM across age groups compared with women.Asbestos consumption in China dramatically dropped since 2012 and reached the bottom in 2017 with 230 kilotons.By 2029,the projected age-standardized rate for incidence and mortality is expected to reach 1.2 per million for both.Conclusion:We found,for the first time using GBD data on the Chinese population,that the burden of MM has been significantly increasing in China over the last three decades and will continue to increase in the upcoming decade,suggesting an urgent need for a complete ban on chrysotile asbestos in China.

针刺临床试验干预措施报告标准的修订:CONSORT声明的扩展

"针刺临床试验干预措施报告标准"(STandards for Reporting Interventions in Clinical Trials of Acupuncture,STRICTA)于2001年和2002年在5种期刊上发表。该指南以对照检查清单及解释的形式供作者和期刊编辑使用,旨在提高针刺临床试验报告的质量,尤其是对其中干预措施的报告,因而有助于对这些试验的解释和重复。随后对STRICTA的应用及影响的述评都强调了STRICTA的价值,也提出了改进和修订的建议。为使修订过程顺利进行,STRICTA工作组、CONSORT工作组和中国Cochrane中心于2008年开始合作。召集成立的有47名成员的专家组对清单的修改稿提出了电子版反馈意见。在后来于弗莱堡(Freiburg)召开的见面会上,由21名专家组成的工作组进一步修订了STRICTA对照检查清单,并计划如何对其进行发布。新的STRICTA对照检查清单作为CONSORT的正式扩展版,包含6项条目及17条二级条目。这些条目为报告针刺治疗的合理性、针刺的细节、治疗方案、其他干预措施、治疗师的背景以及对照或对照干预提供了指南。而且,作为修订工作的一部分,对每一条目作了详尽解释,并针对每一条目给出了报告良好的实例。此外,STRICTA中的"对照"(controlled)一词被替换成了"临床"(clinical),以示STRICTA适用于更广泛的各类临床评价设计,包括非对照结局研究和病例报道。修订的STRICTA对照检查清单有望与CONSORT声明及其非药物治疗扩展版一起共同提高针刺临床试验的报告质量。

The innovations in China’s primary health care reform: Development and characteristics of the community health services in Hangzhou

Objective:This study focuses on Hangzhou,a Chinese city with a population of nine million urban and rural residents,to examine the successful development and innovation experience of its primary health care service system during the new health reform in China since 2009 and then dis-seminate the findings through international third parties.Methods:Measures such as data analysis,study of documents and regulations,fieldwork,and expert discussions were used to systematically investigate primary health care in Hangzhou.The findings will have a profound practical impact on the health reform for nine million rural and urban residents throughout Hangzhou’s municipal boroughs.Results:Community health services in Hangzhou are characterized as follows:They are gov-ernment led;they are guaranteed with enough financing,personnel,facilities,and regulation;sup-ported by the unified information platform;general practitioners have been assigned the key role of health‘gatekeepers’;they provide primary care combined with basic public health services;there are integrated urban and rural health services and insurance coverage;and there is health care-pen-sion-nursing integration and general practitioner-contracted‘smart’services.Preliminary data collection and analysis indicate that the basic health status of Hangzhou residents is superior to that of residents of China as a whole,and some health indicators in Hangzhou are comparable to those in Western developed countries.Conclusion:It is reasonable to believe that the primary health care level in China,including Hangzhou,will be further developed and promoted with indexed performance evaluations and more effective implementation of additional measures.

Detecting decreased sexual health with MDHAQ-S

There are instruments that measure sexual function or sexual health for persons with RA, but since sexual health is a sensitive issue, the hypothesis is that it would be easier to have a standard questionnaire that could indicate the need for communication about sexual health issues instead of an extra questionnaire with more detailed questions on sexual health. The aim of the study is to find out whether sexual health difficulties can be screened by factors included in the MDHAQ-S for persons with RA. This study explores the relation between factors included in the MDHAQ-S and the Sexual Health Questionnaire (QSH) using a mixed methods design combining quantitative and qualitative data. The MDHAQ-S covers sexual health issues, not only by using the question on sexual health, but also on other factors included in the questionnaire such as increased pain, fatigue, depression, anxiety, physical capacity, level of physiccal activity and body weight. To explore decreased sexual arousal, decreased sexual satisfaction and decreased sexual well-being, in-depth interviews must be held with persons with RA, either using a sexual health questionnaire or in a clinical interview.

对瑞典哮喘青少年患者医疗管理、哮喘控制和生活质量的研究

Aim: In Sweden, paediatricians or general practitioners treat most adolescents with asthma. This study compares management, treatment goals and quality of life for adolescents aged 15-18 y in paediatric or primary care. Material and methods: A random sample of patients answered a disease-specific and a quality-of-life (MiniAQLQ) questionnaire. Results: The 146 adolescents in paediatric care had more years with asthma, better continuity of annual surveillance, higher use of inhaled steroids and a stated better knowledge of their asthma than the 174 patients in primary care. No difference could be detected in asthma control or quality of life. Of all 320 adolescents, approximately 20%had woken at night due to asthma symptoms during the last week. About 15%hadmade unscheduled, urgent care visits and a third had used short-acting beta-agonist relievers more than twice a week. Quality-of-life scores were high and similar in both settings. Conclusions: Swedish adolescents with asthma are managed and treated somewhat differently in paediatric and primary care but with equal and, for the most part, satisfying results. The difference between the two settings probably reflects both differences in severity of asthma and different treatment traditions. For all adolescents, better ful-filment of goals regarding symptoms and exacerbations would be desirable, whereas a good quality of life including normal physical activity seems to have been achieved.

Nursing in a Globalized World: Nursing Students with International Study Experience Report Higher Competence at Graduation

Due to globalization, there is a need for nurses with skills and competence in providing safe, competent and culturally appropriate care. The aim of the study was to investigate whether International Study Experiences (ISE) in other countries during basic nursing education had an impact on newly graduated nurses as regards to self-reported competence. Moreover, a second aim was to explore what background factors that facilitated or constituted a hindrance for nursing students to choose to conduct part of their basic nursing education abroad. At 11 Universities/University Colleges (henceforth called Higher Education Institutions [HEIs]) in Sweden, 565 nursing students responded to the Nurse Professional Competence (NPC) Scale. Students with ISE rated their competence significantly higher on three NPC competence areas—“Legislation in nursing and safety planning”, “Leadership and development of nursing” and “Education and supervision of staff/students”. Background factors that significantly seemed to enhance ISE were living alone, not having children or other commitments in relation to family, international focus at the HEI and previous international experience. Lack of financial means was reported to prevent students from choosing ISE. The study implies that several background factors are of importance whether students choose ISE or not. ISE during basic nursing education might result in better self-reported competence in leading and developing nursing care, including education of future nurses, and in providing safe care.

Chemoprophylaxis, diagnosis, treatments, and discharge management of COVID-19: An evidence-based clinical practice guideline(updated version)

The novel severe acute respiratory syndrome coronavirus 2(SARS-CoV-2)is the cause of a rapidly spreading illness,coronavirus disease 2019(COVID-19),affecting more than seventeen million people around the world.Diagnosis and treatment guidelines for clinicians caring for patients are needed.In the early stage,we have issued"A rapid advice guideline for the diagnosis and treatment of 2019 novel coronavirus(2019-nCoV)infected pneumonia(standard version)";now there are many direct evidences emerged and may change some of previous recommendations and it is ripe for develop an evidence-based guideline.We formed a working group of clinical experts and methodologists.The steering group members proposed 29 questions that are relevant to the management of COVID-19 covering the following areas:chemoprophylaxis,diagnosis,treatments,and discharge management.We searched the literature for direct evidence on the management of COVID-19,and assessed its certainty generated recommendations using the Grading of Recommendations,Assessment,Development and Evaluation(GRADE)approach.Recommendations were either strong or weak,or in the form of ungraded consensus-based statement.Finally,we issued 34 statements.Among them,6 were strong recommendations for,14 were weak recommendations for,3 were weak recommendations against and 11 were ungraded consensus-based statement.They covered topics of chemoprophylaxis(including agents and Traditional Chinese Medicine(TCM)agents),diagnosis(including clinical manifestations,reverse transcription-polymerase chain reaction(RT-PCR),respiratory tract specimens,IgM and IgG antibody tests,chest computed tomography,chest X-ray,and CT features of asymptomatic infections),treatments(including lopinavirritonavir,umifenovir,favipiravir,interferon,remdesivir,combination of antiviral drugs,hydroxychloroquine/chloroquine,interleukin-6 inhibitors,interleukin-1 inhibitors,glucocorticoid,qingfei paidu decoction,lianhua qingwen granules/capsules,convalescent plasma,lung transplantation,invasive or noninvasive ventilation,and extracorporeal membrane oxygenation(ECMO)),and discharge management(including discharge criteria and management plan in patients whose RT-PCR retesting shows SARS-CoV-2 positive after discharge).We also created two figures of these recommendations for the implementation purpose.We hope these recommendations can help support healthcare workers caring for COVID-19 patients.

Diagnosis of Liver Involvement in Primary Sj(o)gren Syndrome

Liver involvement was one of the first extraglandular manifestations to be reported in patients with primary Sj(o)gren syndrome (SS).In the 1990s,a study of liver involvement in patients with primary SS integrated the evaluation of clinical signs of liver disease,liver function and a complete panel of autoantibodies.Recent developments in the field of hepatic and viral diseases have significantly changed the diagnostic approach to liver involvement in SS.The most recent studies have shown that,after eliminating hepatotoxic drugs and fatty liver disease,the two main causes of liver disease in primary SS are chronic viral infections and autoimmune liver diseases.The differential diagnosis of liver disease in primary SS (viral vs autoimmune) is clinically important,since the two processes require different therapeutic approaches and have different prognoses.With respect to viral infections,chronic HCV infection is the main cause of liver involvement in SS patients from the Mediterranean area,while chronic HBV infection may be the main cause of liver involvement in SS patients from Asian countries.After eliminating viral hepatitis,primary biliary cirrhosis (PBC) should be considered the main cause of liver disease in primary SS.PBC-related SS patients may have a broad spectrum of abnormalities of the liver,including having no clinical or analytical data suggestive of liver disease.Autoimmune hepatitis (AIH) is the second most frequently found autoimmune liver disease to be associated with SS (all reported cases are type I),and nearly 10% of these patients have an AIH-PBC overlap.Finally,IgG4-related disease must be investigated in patients with SS presenting with sclerosing cholangitis,especially when autoimmune pancreatitis or retroperitoneal fibrosis are also present.

晚发性结直肠癌患者亲属的结肠镜筛查时间间隔:一项全国性匹配队列研究

Colorectal cancer(CRC)is a major global cancer burden,ranking third in terms of incidence,but second in terms of mortality[1].Early detection of CRC through screening combined with subsequent removal of polyps remains a predominant strategy for CRC prevention.Family history is a known risk factor for CRC[2-4].However,only a few screening guidelines provide recommendations for individuals with familial CRC risk[5].

初级医疗保健中罗19巢癌的诊断

全世界每年新发卵巢癌病例超过20万例，约占所有女性癌症病例的4％。总的来说，卵巢癌的5年生存率较低，仅30％～40％。早期卵巢癌的5年生存率在70％以上，仅五分之一的患者能够得以早期诊断。。晚期卵巢癌的5年生存率只有约15％。目前还没有行之有效的筛查方法。

成人慢性心力衰竭的诊断与治疗：最新NICE指南概要

在英国有90万人患有心力衰竭（心衰）。由于缺血性心肌病（心衰患者的主要病因）预后改善和人口老龄化导致了心衰患病率的增加。心衰的两种主要类型为：左室收缩功能（LVEF）异常和LVEF正常的心衰。

Swedish rape offenders——a latent class analysis

Sweden has witnessed an increase in the rates of sexual crimes including rape.Knowledge of who the offenders of these crimes are is therefore of importance for prevention.We aimed to study characteristics of individuals convicted of rape,aggravated rape,attempted rape or attempted aggravated rape(abbreviated rape+),against a woman≥18years of age,in Sweden.By using information from the Swedish Crime Register,offenders between 15 and 60years old convicted of rapeþbetween 2000 and 2015 were included.Information on substance use disorders,previous criminality and psychiatric disorders were retrieved from Swedish population-based registers,and Latent Class Analysis(LCA)was used to identify classes of rapeþoffenders.A total of 3039 offenders were included in the analysis.A major-ity of them were immigrants(n=1800;59.2%)of which a majority(n=1451;47.7%)were born outside of Sweden.The LCA identified two classes:Class A-low offending class(LOC),and Class B—high offending class(HOC).While offenders in the LOC had low rates of previous criminality,psychiatric disorders and substance use disorders,those included in the HOC had high rates of previous criminality,psychiatric disorders and substance use dis-orders.While HOC may be composed by more“traditional”criminals probably known by the police,the LOC may represent individuals not previously known by the police.These two separated classes,as well as our finding in regard to a majority of the offenders being immi-grants,warrants further studies that take into account the contextual characteristics among these offenders.

General practice training in China:A multimodal experiential program provided by Australian educators

Our small group of expert GP academic trainers from Monash University and the University of Melbourne have been collaborating over the last decade to develop a GP model training program based in Luohu,Shenzhen,that deeply engages Chinese GPs and seeks to provide personal and professional development of the GPs.The program is closely linked to continuing offshore GP education in Australia,with many trainees of the program having attended intensive training hosted by Monash University in Australia.

Offshore teaching in chronic disease management:The Monash- Shenzhen experience

The important role of GPs and the high prevalence and burden of chronic disease in China have been discussed in other articles in this series,so there is no need to reiterate this background here.This article deals with the pedagogy of chronic disease management as presented to cohorts of Chinese GPs from Shenzhen attending an offshore program at Monash University in Australia.The program,which commenced in 2010,was 7 weeks in duration and has now expanded to 13 weeks,enabling greater coverage of important topics,more site visits,and instruction in teaching and research methods,along with development of research proposals often based on management of a chronic disease.

预测英格兰和威尔士2型糖尿病的发生风险：QD Score前瞻性推导和验证

目的 开发并验证一个新的糖尿病风险模型（QDScore），用来估计10年内获得糖尿病诊断的风险，该模型的基础建立于多样化的种族和社会经济地位人群。 设计 前瞻性开放性队列研究，使用的数据常规收集于355个英格兰和威尔士全科诊所，然后使用176个独立诊所的数据来验证这一评分。 参与者 该推导模型共包括2540753例患者，年龄25—79岁，产生16436315患者年，其中78081例为新诊断2型糖尿病；验证队列包括1232832例患者（7643037患者年），其中37535例患者为新发2型糖尿病。 结局评估指标 用Cox比例风险模型估计建立队列中风险因子的效应，并且在男性和女件中推导出一个风险公式。终模型中包括的检验预测变量有：自我报告的种族、年龄、性别、体重指数、吸烟状态、糖尿病家族史、Townsend剥夺评分、已接受治疗的高血压、心血管疾病和口前使用糖皮质激素；关注的结局评估指标是在全科诊所记录中新发生的糖尿病。校正和区分度的测定在验证队列中进行计算。 结果 不同种族间2型糖尿病的风险存在4到5倍的变异。与白人参照组相比，巴基斯坦女性的调整风险比为4．07（95％可信区间3．24～5．11），巴基斯坦男性为2．54（2．20～2．93）。巴基斯坦和盂加拉困男性与印度男性相对风险比显著增高。非洲黑人男性和中国女性与对应的白人参照组相比风险增加。在验证数据中，该模型解释了51．53％的女性差异（95％可信区间50．90～52．16）和48．16％的男性差异（47．52～48．80）。风险积分显示了良好的区分能力，女性中D值达2．11（95％可信区间2．08～2．14），男性中为1．97（1．95～2．00）。模型经过很好的校正。 结论 QDScore是第一个基于前瞻性队列研究并且包括了社会等级和种族来预测糖尿病10年风险的风险预测模型。该模型不需要实验室检查，并且可以应用于临床实践，另外，还可以通过一个简单的网络计算器为公众所用（www．qdscore．org）。