Right coronary artery from the left sinus of valsalva:Multislice CT and transradial PCI

A 42-year-old-woman presented with de novo crescendo angina.Thallium-scintigraphy showed inferior ischemia.Coronary angiogram revealed a right coronary artery(RCA),originating from the left sinus of Valsalva with a severe proximal systolic compression.She underwent successful transradial percutaneous coronary intervention with stent implantation.Multislice-computed tomography(MSCT) is usually used to evaluate coronary artery anomalies and can effectively show the anomalous RCA and the inter-arterial trajectory between the aorta and pulmonary arteries.Anomalies of the origin of the coronary arteries are rare,but can produce specific clinicopathological entities that should be diagnosed with accuracy.This case report illustrates the role of MSCT in the detailed description of an abnormal coronary artery and the use of stenting for symptoms relief.

Acute myocarditis triggering coronary spasm and mimicking acute myocardial infarction

A 24-year-old healthy man consulted to our center because of typical on-and-off chest-pain and an electrocardiogram showing ST-segment elevation in inferior leads. An urgent coronary angiography showed angiographically normal coronary arteries. Cardiovascular magnetic resonance imaging confirmed acute myocarditis. Although acute myocarditis triggering coronary spasm is an uncommon association, it is important to recognize it, particularly for the management for those patients presenting with ST-segment elevation and suspect myocardial infarction and angiographically normal coronary arteries. The present report highlights the role of cardiovascular magnetic resonance imaging to identify acute myocarditis as the underlying cause.

Bioactivity of mackerel peptides on obesity and insulin resistance,an in-vivo study

Of many metabolic irregularity risk factors,glucose intolerance,insulin resistance,and abdominal obesity are the main ones.The risk of vascular diseases and cancers is rather high in such individuals therefore its treatment and prevention are equally important for the health of population.Marine including fish biopeptides have frequently shown to prevent and or ameliorate these risk factors.In our earlier studies,Atlantic mackerel hydrolysate and its fractions showed promising effects on immunity and hypertension.We,therefore,in the current study,aimed to examine the effects of mackerel hydrolysate along its cationic peptides,isolated at pH3 using electrodialysis with ultrafiltration membrane,on metabolic disorder factors in diet-induced insulin resistant obese mice.Mice were fed the chow and or the hypercaloric diet (high fat high sucrose) for the duration of 8-weeks.Subsequently the hypercaloric fed insulin resistant obese mice were gavaged daily either the vehicle and or the test material at the dosage of 208 mg of sample protein per kg mice body weight.According to our observations,mackerel peptides could not effectively modulate food intake,weight gain,adiposity,plasma glucose and insulin concentrations,hepatic cholesterol,and triglyceride levels.Thus,obesity and metabolic impairments could not be averted by the treatments in insulin resistant obese mice.In conclusion,anti-hypertensive,and immunomodulatory attributes of mackerel peptides at the tested concentrations do not seem to be correlated with its metabolic syndrome benefiting effects.To presume a general statement about the metabolic syndrome benefiting potency of Atlantic mackerel's biopeptides further research is warranted.