Chronic kidney disease(CKD) is a widespread renal disease throughout the world. Once it develops to the advanced stage, serious complications and high risk of death will follow. Hence, early screening is crucial for t...Chronic kidney disease(CKD) is a widespread renal disease throughout the world. Once it develops to the advanced stage, serious complications and high risk of death will follow. Hence, early screening is crucial for the treatment of CKD. Since ultrasonography has no side effects and enables radiologists to dynamically observe the morphology and pathological features of the kidney, it is commonly used for kidney examination. In this study,we propose a novel convolutional neural network(CNN) framework named the texture branch network to screen CKD based on ultrasound images. This introduces a texture branch into a typical CNN to extract and optimize texture features. The model can automatically generate texture features and deep features from input images, and use the fused information as the basis of classification. Furthermore, we train the base part of the network by means of transfer learning, and conduct experiments on a dataset with 226 ultrasound images. Experimental results demonstrate the effectiveness of the proposed approach, achieving an accuracy of 96.01% and a sensitivity of 99.44%.展开更多
基金the Zhejiang Provincial Natural Science Foundation of China (No. LY18F020034)the Zhejiang Provincial Medical Health Science and Technology Project+5 种基金China(No. 2014KYB320)the National Natural Science Foundation of China (Nos. 61801428 and 61672543)the Zhejiang University Education FoundationChina (Nos. K18-511120-004 and K17-511120-017)the Major Scientific Project of Zhejiang LabChina (No. 2018DG0ZX01)。
文摘Chronic kidney disease(CKD) is a widespread renal disease throughout the world. Once it develops to the advanced stage, serious complications and high risk of death will follow. Hence, early screening is crucial for the treatment of CKD. Since ultrasonography has no side effects and enables radiologists to dynamically observe the morphology and pathological features of the kidney, it is commonly used for kidney examination. In this study,we propose a novel convolutional neural network(CNN) framework named the texture branch network to screen CKD based on ultrasound images. This introduces a texture branch into a typical CNN to extract and optimize texture features. The model can automatically generate texture features and deep features from input images, and use the fused information as the basis of classification. Furthermore, we train the base part of the network by means of transfer learning, and conduct experiments on a dataset with 226 ultrasound images. Experimental results demonstrate the effectiveness of the proposed approach, achieving an accuracy of 96.01% and a sensitivity of 99.44%.