Bioactive metabolites produced by different endophytic fungi have wide range of applications in pharmaceutical and herbal medicine research.In contrast to plants,they are barely investigated to their boundless possibi...Bioactive metabolites produced by different endophytic fungi have wide range of applications in pharmaceutical and herbal medicine research.In contrast to plants,they are barely investigated to their boundless possibilities as storehouses of novel bioactive metabolites.They produce diverse metabolites by different biosynthetic pathways with the host plant.Enthusiasm for endophytes as a characteristic asset for new drugs was roused by the disclosure of paclitaxel-producing endophytic fungi.Anticancer activity is by and large connected with the cytotoxicity of the compounds present in the endophytic fungi.Phylogenetic classification of endophytic fungi is of great interest to mycologists as they can produce novel bioactive compounds with antitumor activity.This article audits anticancer compounds derived from endophytic fungi disengaged from the separate host plant.The endophytic fungi have been grouped by their host plants and anticancer compound synthesized.展开更多
Objective:To investigate the bioactive components of a coastal medicinal plant,Hyptis suaveolens(L.)Poit.(H.suaveolens)leaves using fourier transform-infrared spectroscopy and gas chromatography-mass spectrometer(GC-M...Objective:To investigate the bioactive components of a coastal medicinal plant,Hyptis suaveolens(L.)Poit.(H.suaveolens)leaves using fourier transform-infrared spectroscopy and gas chromatography-mass spectrometer(GC-MS).Methods:The chemical compositions of the ethanol extract of whole plant of H.suaveolens was investigated using PerkinElmer GC-MS,while the mass spectra of the compounds found in the extract was matched with the National Institute of Standard and Technology library.Results:The results of fourier transform-infrared spectroscopy analysis confirmed the presence of secondary alcohols,phenols,alkanes,alkynes,aromatics,nitro compounds and aliphatic compounds.GC-MS analysis of the ethanolic extract revealed the existence of 30 phytochemical compounds.5,5-Dimethylimidazolidin-2,4-diamine(20.35%)was found to be the major compound.Conclusions:The results of this study offer a platform to use H.suaveolens leaves as herbal alternative for various diseases.展开更多
文摘Bioactive metabolites produced by different endophytic fungi have wide range of applications in pharmaceutical and herbal medicine research.In contrast to plants,they are barely investigated to their boundless possibilities as storehouses of novel bioactive metabolites.They produce diverse metabolites by different biosynthetic pathways with the host plant.Enthusiasm for endophytes as a characteristic asset for new drugs was roused by the disclosure of paclitaxel-producing endophytic fungi.Anticancer activity is by and large connected with the cytotoxicity of the compounds present in the endophytic fungi.Phylogenetic classification of endophytic fungi is of great interest to mycologists as they can produce novel bioactive compounds with antitumor activity.This article audits anticancer compounds derived from endophytic fungi disengaged from the separate host plant.The endophytic fungi have been grouped by their host plants and anticancer compound synthesized.
文摘Objective:To investigate the bioactive components of a coastal medicinal plant,Hyptis suaveolens(L.)Poit.(H.suaveolens)leaves using fourier transform-infrared spectroscopy and gas chromatography-mass spectrometer(GC-MS).Methods:The chemical compositions of the ethanol extract of whole plant of H.suaveolens was investigated using PerkinElmer GC-MS,while the mass spectra of the compounds found in the extract was matched with the National Institute of Standard and Technology library.Results:The results of fourier transform-infrared spectroscopy analysis confirmed the presence of secondary alcohols,phenols,alkanes,alkynes,aromatics,nitro compounds and aliphatic compounds.GC-MS analysis of the ethanolic extract revealed the existence of 30 phytochemical compounds.5,5-Dimethylimidazolidin-2,4-diamine(20.35%)was found to be the major compound.Conclusions:The results of this study offer a platform to use H.suaveolens leaves as herbal alternative for various diseases.
