Aim: To determine the epidemiological, diagnosis and treatment of secondary bone cancer at the National Hospital University Hubert Koutoukou Maga of Cotonou. Patients and Method: It was a retrospective descriptive cro...Aim: To determine the epidemiological, diagnosis and treatment of secondary bone cancer at the National Hospital University Hubert Koutoukou Maga of Cotonou. Patients and Method: It was a retrospective descriptive cross-sectional study carried out from January 1999 to December 2013 on the records of patients treated in the rheumatology department. The selected files had radiological images of tumor appearance objectified by two radiologists. The diagnosis of secondary bone cancer was confirmed after a bone biopsy or the discovery of a primitive tumor site. Patients with hematologic malignancy and incomplete or insufficiently explored records were excluded. Results: Among 10,292 patients followed in the service, 51 (0.5%) had documented bone metastasis. The sex ratio was 1.83. The mean age of patients was 54 ± 9 [26-85] years, with 53% of those over 60 years old. Secondary cancers were on the spine (74.5%), pelvis (35.3%) and the long bones (39.2%). The primary cancer most frequently found was that of the prostate and breast (45.1% and 27.6%, respectively) followed by genital and digestive cancers (9.8% and 7.8%, respectively). Treatment was dominated by hormone therapy (83%) bisphosphonates (70.5%) and chemotherapy (57%). Conclusion: The profile of bone cancer in Benin hospital is very diverse and dominated by the types and osteolytic ostéocondensant. Primary cancers were dominated by the prostate and breast. Bisphosphonates took an important place in the treatment of the disease.展开更多
Objective: To determine the frequency and impact of metabolic syndrome (MS) in patients with low back pain in rheumatology unit in Benin. Patients and Methods: Analytic cross-sectional study conducted between June and...Objective: To determine the frequency and impact of metabolic syndrome (MS) in patients with low back pain in rheumatology unit in Benin. Patients and Methods: Analytic cross-sectional study conducted between June and December 2016 in the rheumatology hospital unit of National Hospital University Hubert Koutoukou Maga of Cotonou. 82 patients with mechanical low back pain were selected. The prevalence of MS was defined using the criteria of the International Diabetes Federation 2005. The data were analyzed using epi data and SPSS17.0 software. Results: The mean age was 50.4 ± 14.9 [12 - 90] years. The sex ratio was 0.82. 29.3% patients have met diagnostic criteria for MS. The mean duration of back pain was 40 ± 17.2 [3 - 120] days. Diseases associated with low back pain were as follow: lumbar intervertebral disk degeneration (34.1%), disk herniation (13.4%), facet joint arthrosis (18.3%), degenerative spondylolisthesis (11%), degenerative lumbar spinal stenosis (6.1%) and related forms (17.1%). MS observed in 24 patients was characterized by the frequent association of abdominal obesity (24 cases), arterial hypertension (22 cases), HDL hypocholesterolemia (8 cases), hyperglycemia (12 cases) or hypertriglyceridemia (7 cases). The presence of the MS was associated with a decreased response to the medical treatment (p 0.01). Conclusion: The MS is frequent in patients with low back pain in rheumatology unit at Cotonou and influence the treatment response. The management of these patients must be integrated into a multidisciplinary approach including the rheumatologist and nutritionist.展开更多
文摘Aim: To determine the epidemiological, diagnosis and treatment of secondary bone cancer at the National Hospital University Hubert Koutoukou Maga of Cotonou. Patients and Method: It was a retrospective descriptive cross-sectional study carried out from January 1999 to December 2013 on the records of patients treated in the rheumatology department. The selected files had radiological images of tumor appearance objectified by two radiologists. The diagnosis of secondary bone cancer was confirmed after a bone biopsy or the discovery of a primitive tumor site. Patients with hematologic malignancy and incomplete or insufficiently explored records were excluded. Results: Among 10,292 patients followed in the service, 51 (0.5%) had documented bone metastasis. The sex ratio was 1.83. The mean age of patients was 54 ± 9 [26-85] years, with 53% of those over 60 years old. Secondary cancers were on the spine (74.5%), pelvis (35.3%) and the long bones (39.2%). The primary cancer most frequently found was that of the prostate and breast (45.1% and 27.6%, respectively) followed by genital and digestive cancers (9.8% and 7.8%, respectively). Treatment was dominated by hormone therapy (83%) bisphosphonates (70.5%) and chemotherapy (57%). Conclusion: The profile of bone cancer in Benin hospital is very diverse and dominated by the types and osteolytic ostéocondensant. Primary cancers were dominated by the prostate and breast. Bisphosphonates took an important place in the treatment of the disease.
文摘Objective: To determine the frequency and impact of metabolic syndrome (MS) in patients with low back pain in rheumatology unit in Benin. Patients and Methods: Analytic cross-sectional study conducted between June and December 2016 in the rheumatology hospital unit of National Hospital University Hubert Koutoukou Maga of Cotonou. 82 patients with mechanical low back pain were selected. The prevalence of MS was defined using the criteria of the International Diabetes Federation 2005. The data were analyzed using epi data and SPSS17.0 software. Results: The mean age was 50.4 ± 14.9 [12 - 90] years. The sex ratio was 0.82. 29.3% patients have met diagnostic criteria for MS. The mean duration of back pain was 40 ± 17.2 [3 - 120] days. Diseases associated with low back pain were as follow: lumbar intervertebral disk degeneration (34.1%), disk herniation (13.4%), facet joint arthrosis (18.3%), degenerative spondylolisthesis (11%), degenerative lumbar spinal stenosis (6.1%) and related forms (17.1%). MS observed in 24 patients was characterized by the frequent association of abdominal obesity (24 cases), arterial hypertension (22 cases), HDL hypocholesterolemia (8 cases), hyperglycemia (12 cases) or hypertriglyceridemia (7 cases). The presence of the MS was associated with a decreased response to the medical treatment (p 0.01). Conclusion: The MS is frequent in patients with low back pain in rheumatology unit at Cotonou and influence the treatment response. The management of these patients must be integrated into a multidisciplinary approach including the rheumatologist and nutritionist.
