Assessment of posterior vitreous detachment on enhanced high density line optical coherence tomography

The state of the vitreo-retinal interface affects various retinal diseases, and the presence or absence of a posterior vitreous detachment （PVD） is one of the most important factors. As such, various studies studying PVD in relation to retinal disease have been performed.

特发性黄斑旁中心凹毛细血管扩张伴黄斑裂孔形成

Background:To report the occurrence of a full thickness macular hole in association with idiopathic parafoveal telangiectasia.Methods:Observational case report.Results:A 60-year-old female with a history of bilateral idiopathic parafoveal telangiectasia presented with acute complaints of decreased vision and metamorphopsia in her right eye.The patient’s retinal examination was significant for idiopathic parafoveal telangiectasia bilaterally,and a new,full-thickness macular hole in the right eye which was confirmed by optical coherence tomography.Conclusions:Full-thickness macular hole formation may occur in conjunction with idiopathic parafoveal telangiectasia,which has not been reported to date.Idiopathic parafoveal telangiectasia,IPT,is a clinical entity with distinct biomicroscopic and fluorescein angiographic findings which may be divided into developmental and acquired forms.Idiopathic macular hole formation is a relatively common condition,which tends to occur more frequently in females in their 7th and 8th decades of life.Idiopathic parafoveal telangiectasia has been reported in association with lamellar macular holes,but,to our knowledge,not with a full thickness macular hole.Here in we report the case of a patient with bilateral idiopathic parafoveal telangiectasia who developed a full-thickness macular hole.

玻璃体内注射曲安西龙治疗视网膜中央静脉阻塞所致的黄斑水肿

Purpose:To investigate the efficacy of intravitreal triamcinolone as treatment for macular oedema in central retinal vein occlusion(CRVO).Methods:We conducted a retrospective comparative case series of nine patients with macular oedema associated with CRVO(six non-ischaemic and three ischaemic)treated with an intravitreal injection of 4 mg triamcinolone acetonide,compared with 10 control(observation)patients(six non-ischaemic and four ischaemic).Examination included visual acuity(VA)tests and complete ophthalmic examinations at baseline,1,2 and 6 months postoperatively.Results:The mean baseline VA was 20/161 for CRVO treatment group patients and 20/75 for observation group patients(P=0.15).No significant difference in VA between CRVO treatment group patients(20/99)and controls(20/282)was observed at the final 6-month visit(p=0.33).Subgroup analysis of the non-ischaemic CRVO treatment patients compared with the non-ischaemic controls also showed no significant difference at the 6-month visit(20/59 and 20/100,respectively;p=0.20).At 6 months,five of the six nonischaemic treated patients had VA≥ 20/100,compared with five of the six non-ischaemic control patients.All patients tolerated the procedure well,but there was a significant increase in intraocular pressure by the 2-month visit(P=0.015).Conclusions:Intravitreal injection of triamcinolone may not be effective for treatment of macular oedema in all CRVO patients or all nonischaemic CRVO patients.A trend towards VA improvement was noted but was not statistically significant.Although our treatment was not hindered by severe complications,there was a significant increase in IOP in the 2 months following treatment.