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Clinicopathological and molecular insights into odontogenic tumors associated with syndromes:A comprehensive review
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作者 Lauren Frenzel Schuch Felipe Martins Silveira +4 位作者 Vanesa Pereira-Prado Estefania Sicco Deepak Pandiar Mariana Villarroel-Dorrego Ronell Bologna-Molina 《World Journal of Experimental Medicine》 2024年第4期96-103,共8页
The association between genetic syndromes and odontogenic tumors encompasses several entities,reflecting the intricate interplay between genetic factors and the development of these lesions.The present study aimed to ... The association between genetic syndromes and odontogenic tumors encompasses several entities,reflecting the intricate interplay between genetic factors and the development of these lesions.The present study aimed to comprehensively investigate the associations between genetic syndromes and odontogenic tumors.We delineated the diverse spectrum of syndromic connections,including key syndromes such as Gardner syndrome,Gorlin syndrome,Schimmelpenning syndrome,and others.Our findings underscore the clinical significance of recognizing odontogenic tumors associated with genetic syndromes as diagnostic indicators for early intervention.We advocate for multidisciplinary collaboration among clinicians,geneticists,and researchers to deepen our understanding of the underlying mechanisms driving these syndromic associations.In light of this,our study contributes to the growing body of knowledge in dentistry and medical genetics,offering insights that may inform clinical practice and enhance patient care for individuals affected by genetic syndromes and odontogenic tumors. 展开更多
关键词 Genetic syndrome Odontogenic tumors Head and neck tumors MISDIAGNOSIS Genetic mutations
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