Morphine and other opioids are among the most effective analgesics for treating pain.However,drug dependence and other deleterious side effects of opioids have limited their clinical applicability.Recent studies sugge...Morphine and other opioids are among the most effective analgesics for treating pain.However,drug dependence and other deleterious side effects of opioids have limited their clinical applicability.Recent studies suggest that the use of opioids for pain control may even exacerbate disease outcomes in some pain-producing conditions,such as acute pancreatitis[1].展开更多
基金supported by the National Key R&D Program of China (2019YFC1709101)The Project First-Class Disciplines Development of Chengdu University of TCM (CZYHW1901)+2 种基金Sao Paulo Research Foundation (FAPESP 2018/07366-4)the National Natural Science Foundation of China (81904312 and 81774437)the Sichuan Science and Technology Program,China (2019YFH0108,2018HH0123,and 2018SZ0257)。
文摘Morphine and other opioids are among the most effective analgesics for treating pain.However,drug dependence and other deleterious side effects of opioids have limited their clinical applicability.Recent studies suggest that the use of opioids for pain control may even exacerbate disease outcomes in some pain-producing conditions,such as acute pancreatitis[1].