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Use of eschar swab DNA to diagnose Rickettsia conorii subspecies conorii infection in Crimea:A case report
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作者 Emine E.Alieva Muniver T.Gafarova +3 位作者 Eugene I.Bondarenko Igor A.Dovgan Irina I.Osiptchuk Marina E.Eremeeva 《Infectious Medicine》 2023年第4期338-342,共5页
Mediterranean spotted fever(MSF)has been diagnosed clinically in the Crimean Peninsula since the 1930s.We describe the recent illness of an elderly patient from Crimea who had developed a classic triad of MSF symptoms... Mediterranean spotted fever(MSF)has been diagnosed clinically in the Crimean Peninsula since the 1930s.We describe the recent illness of an elderly patient from Crimea who had developed a classic triad of MSF symptoms consisting of fever,maculopapular rash,and eschar.Clinical diagnosis of rickettsiosis was confirmed using real-time PCR and sequencing of 4 Rickettsia protein genes.The strain causing clinical illness was characterized as Rickettsia conorii subspecies conorii Malish 7.This report corroborates the utility of eschar swab material as a source of DNA for PCR-based diagnostics that enables timely patient treatment and management. 展开更多
关键词 ESCHAR Mediterranean spotted fever PCR Rickettsia conorii SWAB
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