Electrostatic microelectromechanical (MEMS) switches are the basic building blocks for various radio-frequency (RF) transceivers. However, conventional cantilever-based designs of MEMS switches require a large actuati...Electrostatic microelectromechanical (MEMS) switches are the basic building blocks for various radio-frequency (RF) transceivers. However, conventional cantilever-based designs of MEMS switches require a large actuation voltage, exhibit limited RF performance, and suffer from many performance tradeoffs due to their flat geometries restricted in two dimensions (2D). Here, by leveraging the residual stress in thin films, we report a novel development of three-dimensional (3D) wavy microstructures, which offer the potential to serve as high-performance RF switches. Relying on standard IC-compatible metallic materials, we devise a simple fabrication process to repeatedly manufacture out-of-plane wavy beams with controllable bending profiles and yields reaching 100%. We then demonstrate the utility of such metallic wavy beams as RF switches achieving both extremely low actuation voltage and improved RF performance owing to their unique geometry, which is tunable in three dimensions and exceeds the capabilities of current state-of-the-art flat-cantilever switches with 2D-restricted topology. As such, the wavy cantilever switch presented in this work actuates at voltages as low as 24 V while simultaneously exhibiting RF isolation and insertion loss of 20 dB and 0.75 dB, respectively, for frequencies up to 40 GHz. Wavy switch designs with 3D geometries break through the design limits set by traditional flat cantilevers and provide an additional degree of freedom or control knob in the switch design process, which could enable further optimization of switching networks used in current 5G and upcoming 6G communication scenarios.展开更多
Melanoma is a serious malignant skin tumor.Effectively eliminating melanoma and healing after-surgical wounds are always challenges in clinical studies.To address these problems,we propose manganese-doped calcium sili...Melanoma is a serious malignant skin tumor.Effectively eliminating melanoma and healing after-surgical wounds are always challenges in clinical studies.To address these problems,we propose manganese-doped calcium silicate nanowire-incorporated alginate hydrogels(named MCSA hydrogels)for in situ photothermal ablation of melanoma followed by the wound healing process.The proposed MCSA hydrogel had controllable gelation properties,reasonable strength,and excellent bioactivity due to the incorporated calcium silicate nanowires as the in situ cross-linking agents and bioactive components.The doping of manganese into calcium silicate nanowires gave them excellent photothermal effects for eradicating melanoma effectively under near infrared(NIR)irradiation.Moreover,the synergistic effect of manganese and silicon in the MCSA hydrogel effectively promotes migration and proliferation of vascular endothelial cells and promotes angiogenesis.Hence,such bifunctional bioactive hydrogels could achieve combined functions of photothermal therapy and wound healing,showing great promise for melanoma therapy and tissue regeneration.展开更多
基金This work was supported in part by the Scientific and Technological Research Council of Turkey(TUBITAK)grant number 118E842,the Turkish Academy of Sciences(TUBA)Outstanding Young Scientist Award(TUBA-GEBIP)to Murat Kaya Yapici,and Sabanci University.Rayan Bajwa also acknowledges the support of the Higher Education Council(HEC)of Pakistan for supporting graduate studies.
文摘Electrostatic microelectromechanical (MEMS) switches are the basic building blocks for various radio-frequency (RF) transceivers. However, conventional cantilever-based designs of MEMS switches require a large actuation voltage, exhibit limited RF performance, and suffer from many performance tradeoffs due to their flat geometries restricted in two dimensions (2D). Here, by leveraging the residual stress in thin films, we report a novel development of three-dimensional (3D) wavy microstructures, which offer the potential to serve as high-performance RF switches. Relying on standard IC-compatible metallic materials, we devise a simple fabrication process to repeatedly manufacture out-of-plane wavy beams with controllable bending profiles and yields reaching 100%. We then demonstrate the utility of such metallic wavy beams as RF switches achieving both extremely low actuation voltage and improved RF performance owing to their unique geometry, which is tunable in three dimensions and exceeds the capabilities of current state-of-the-art flat-cantilever switches with 2D-restricted topology. As such, the wavy cantilever switch presented in this work actuates at voltages as low as 24 V while simultaneously exhibiting RF isolation and insertion loss of 20 dB and 0.75 dB, respectively, for frequencies up to 40 GHz. Wavy switch designs with 3D geometries break through the design limits set by traditional flat cantilevers and provide an additional degree of freedom or control knob in the switch design process, which could enable further optimization of switching networks used in current 5G and upcoming 6G communication scenarios.
基金supported by the National Natural Science Foundation of China(81771989)Innovation Cross Team of the Chinese Academy of Sciences(JCTD-2018-13)Science and Technology Commission of Shanghai Munici-pality(20490713900).
文摘Melanoma is a serious malignant skin tumor.Effectively eliminating melanoma and healing after-surgical wounds are always challenges in clinical studies.To address these problems,we propose manganese-doped calcium silicate nanowire-incorporated alginate hydrogels(named MCSA hydrogels)for in situ photothermal ablation of melanoma followed by the wound healing process.The proposed MCSA hydrogel had controllable gelation properties,reasonable strength,and excellent bioactivity due to the incorporated calcium silicate nanowires as the in situ cross-linking agents and bioactive components.The doping of manganese into calcium silicate nanowires gave them excellent photothermal effects for eradicating melanoma effectively under near infrared(NIR)irradiation.Moreover,the synergistic effect of manganese and silicon in the MCSA hydrogel effectively promotes migration and proliferation of vascular endothelial cells and promotes angiogenesis.Hence,such bifunctional bioactive hydrogels could achieve combined functions of photothermal therapy and wound healing,showing great promise for melanoma therapy and tissue regeneration.