Self reported adherence to antiretroviral treatment and correlates in Hunan province,the Peoples Republic of China

Aims:This study aimed to describe the adherence level to antiretroviral therapy and its associated factors among people living with HIV in Hunan province,China.Methods:Across-sectional survey study was done at two major HIV treatment sites within Hunan province in China from July 2011 to Oct 2012 through face-to-face interviews.Adherence measures were captured using a 30-day visual analog scale(VAS).Results:A total of 418 participants consented and completed the questionnaires with the mean age being 38 years old.Based on VAS,28%of the participants had lower than 90%ART adherence level.The main reasons for missing drugs were;forgetting,being away from home,being busy and feeling worse after taking drugs.Logistic regression results showed that drug use(B=0.68,OR=2.11),time on ART(B=0.31,OR=0.72)and side effects(B=0.64,OR=1.82)were significantly associated with adherence to ART.Conclusion:Patients on ARVs in Hunan province are faced with adherence challenges notably drug abuse,drug regime scheduling challenges at the initial stages of therapy and drug side effects.It is therefore necessary to institute specific adherence interventions that target those who abuse drugs,ART naïve patients,and those experiencing side effects in order to achieve optimal ART adherence.

女性艾滋病风险感知及安全套使用相关因素的调查研究

目的全球范围内中老年女性人类免疫缺陷病毒(human immunodeficiency virus,HIV)阳性病例有明显增加趋势。本研究旨调查湖南省40岁及以上女性对HIV感染风险的感知、艾滋病相关知识和态度、安全套使用情况及关联因素。方法2019年7月至2020年8月,对湖南省4个地区的958名40岁及以上女性进行横断面调查。收集其社会人口学特征、HIV感染风险感知、艾滋病知识和态度、安全套使用和其他安全性行为的相关资料。使用单因素和多因素logistic回归分析来确定安全套使用的关联因素。结果在958名调查对象中,60.6%认为自己没有感染艾滋病毒的风险,46.8%报告他们在过去的性生活中从未使用过安全套。年龄较大、家庭月收入较低、在过去1年没有接受过艾滋病相关教育、不愿意使用避孕套或无法在性行为时决定安全套的使用、对艾滋病态度更消极的女性在性行为过程中使用安全套的可能性较小。结论调查显示多数40岁及以上的女性认为自己感染HIV的风险很低,性行为过程中安全套使用率也很低。未来应针对这一群体加强艾滋病预防和控制相关知识教育。