Transforming growth factor-β(TGF-β)is a multifunctional regulatory molecule existing in a wide variety of both normal and neoplastic cells. In order to evaluate the structure-function relationship of TGF-β, we have...Transforming growth factor-β(TGF-β)is a multifunctional regulatory molecule existing in a wide variety of both normal and neoplastic cells. In order to evaluate the structure-function relationship of TGF-β, we have synthesized a series of its important fragments by manual stepwise solid-phase methodology and studied their biological activity. In展开更多
The evidence on the length-regulation in the self-association of actin is conflicting andits interpretation relies heavily on the character of the measurement method. By quasi-elastically light scattering (QELS) measu...The evidence on the length-regulation in the self-association of actin is conflicting andits interpretation relies heavily on the character of the measurement method. By quasi-elastically light scattering (QELS) measurements. the change of the polymerlength as a function of time and the effect of ATP have been studied. QELS studies re-vealed that there is a length-regulation stage in self-association of actin which is not in-展开更多
文摘Transforming growth factor-β(TGF-β)is a multifunctional regulatory molecule existing in a wide variety of both normal and neoplastic cells. In order to evaluate the structure-function relationship of TGF-β, we have synthesized a series of its important fragments by manual stepwise solid-phase methodology and studied their biological activity. In
基金Project supported by the State Commission of Science and Technology and the National Natural Science Foundation of China.
文摘The evidence on the length-regulation in the self-association of actin is conflicting andits interpretation relies heavily on the character of the measurement method. By quasi-elastically light scattering (QELS) measurements. the change of the polymerlength as a function of time and the effect of ATP have been studied. QELS studies re-vealed that there is a length-regulation stage in self-association of actin which is not in-
