A mild and efficient synthesis of N-substituted-3-aryl-3-（2-hydroxy-4,4-dimethyl-6-oxocyclohex-l- enyl）propanamides via four-component reaction of an aldehyde, amine, Meldrum＇s acid and 5,5-dimethylcyclo- hexane-1,...A mild and efficient synthesis of N-substituted-3-aryl-3-（2-hydroxy-4,4-dimethyl-6-oxocyclohex-l- enyl）propanamides via four-component reaction of an aldehyde, amine, Meldrum＇s acid and 5,5-dimethylcyclo- hexane-1,3-dione in the presence of benzyltriethylammonium chloride （TEBAC） in aqueous medium is described. This method has the advantages of accessible starting materials, good yields, mild reaction conditions and eco- friendliness.展开更多
文摘A mild and efficient synthesis of N-substituted-3-aryl-3-（2-hydroxy-4,4-dimethyl-6-oxocyclohex-l- enyl）propanamides via four-component reaction of an aldehyde, amine, Meldrum＇s acid and 5,5-dimethylcyclo- hexane-1,3-dione in the presence of benzyltriethylammonium chloride （TEBAC） in aqueous medium is described. This method has the advantages of accessible starting materials, good yields, mild reaction conditions and eco- friendliness.
