Symptom characteristics and prevalence of qi deficiency syndrome in people of varied health status and ages: A multicenter cross-sectional study

Objective:Aging caused by a deficiency syndrome can be found in ancient and modern traditional Chinese medicine literature.Qi deficiency syndrome(QDS)is a vital factor in the aging process.This study aimed to establish a full-scale trial to evaluate the prevalence,symptom severity,frequency,and distribution of QDS in different age groups and varying health status to elucidate the role of qi deficiency in the aging process and deterioration of health.Methods:This cross-sectional study was conducted in four hospitals in China,and data from 1220 participants were included.The participants,aged between 20 and 79 years,completed questionnaires that recorded prevalence of QDS and severity or frequency of relevant symptoms,then were interviewed by investigators.We used frequency analysis and chi-squared tests to perform comparative analysis of prevalence in different age and health groups;we used a ranksum tests for quantitative analysis of symptoms severity and frequency scores;we performed a regression analysis of correlation between syndrome occurrence and potential factors using nonconditional binary logistic stepwise regression of numerical variables.P<0.05 was considered statistically significant.Results:Prevalence,symptom severity and frequency scores of QDS showed a rising trend when physical condition worsened,rather than when age increased.Health status,fatigue,shortness of breath or no desire to talk,spontaneous sweating,swollen tongue with teeth marks on side,and deficient and weak pulse,rather than increasing age were contributing factors to this syndrome.Distribution of QDS in certain health and age stages showed remarkable irregularities.Conclusions:Qi deficiency may be a contributing factor for sub-health(sub-optimal health)and chronic diseases rather than aging.It may play a crucial role in chronic disease pathogenesis of young and middle-aged people,and in sub-health pathogenesis of older adults.Recognition of the warning signs and symptoms of QDS may lead to early intervention and prevention of subhealth,and chronic diseases.

A review of the graded treatment strategy for SARS-CoV-2 pneumonia

The emergence of the 2019 novel coronavirus(2019-nCoV)from China has triggered a worldwide outbreak of viral pneumonia.With the rapid outbreak,frontline clinical researchers are exploring experimental treatments.We searched Pubmed,Web of Science,BMJ(British medical association),Cochrane library,Elsevier Science Direct,OUP(Oxford University Press),and CUP(Cambridge university press)databases.A total of 67 articles of literature and studies on COVID-19 therapy were searched and screened.Literature and research sources include China and other English-speaking countries such as Europe and the United States.We obtained and summarised the current treatment regimens for COVID-19,including antiviral therapy,hormone therapy,oxygen therapy,routine therapy,and rehabilitation therapy,and standardized the above regimens.We reviewed the indications,adverse reactions,and timing of this treatment regimen.Hopefully,it will help those countries that are in the midst of an outbreak.As for treatment for COVID-19,clinicians need a professional and comprehensive treatment program,which has high requirements for the hospital's treatment equipment and management standards,drug development and use standards,national financial support,physicians'treatment level and patients'active cooperation.