The relationship of pulse pressure and left ventricular funcion in hypertension patients

AIM:Discuss the relationship of pulse pr essure and left ventricular functio n in hypertensive patients.METHODS:We observed the relationship of the pulse pressure and the times of again occurred coronary artery diseases,left ventricular fore and after span,lef t ventricular back wall thickness an d left ventricular ejection fraction(EF)by color Doppler ultrasound in hypertensive patients.RESULTS:The times of again occurred coronary artery diseases,the left ventricular fore and after s pan and left ventricular EF of each pulse pressure group were significantly d ifference(P<0.05,P<0.01).CONCLUSION:The pulse pressure may take part in th e further impair of left ventricular function coronary artery diseases.Control the pulse p ressure coronary artery diseases have an imp ortant meaning in decreasing the fur ther impair of left ventricular function.

Coronary artery disease in Chinese adults with type 2 diabetes mellitus estimated by electron beam computed tomography and electron beam computed tomography angiography

Objective To assess the prevalence and risk of coronary artery disease(CAD)in Chinese adults with type 2 diabetes mellitus(T2DM)using electron beam computed tomography(EBCT)and EBCT angiography(EBCTA).Methods:Ninety-four cases were enrolled in this study including diabetes(n=28),impaired glucose tolerance(IGT,n=30),coronary heart disease(CHD,n=11),and control(n=25).Cardiac EBCT plain scanning and EBCTA were performed on all of these subjects to evaluate coronary artery calcifica-tion(CAC)scores,and number of segments of stenosed coronary arteries.Both CAC and/or coronary artery stenosis were defined as patients with coronary artery lesions(CAL).Results CAC scores were not different with the control,diabetes,IGT,or CHD(P>0.05)groups.Compared to control(0.520±1.295),more stenosed coronary arteries segments(P<0.05)were detected in diabetes(2.964±1.915),IGT(2.200±2.024),and CHD(2.273±1.679).Number of stenosed artery segments were correlated with age(r=0.215,P=0.019),postprandial glucose(r=0.224,P=0.015),total cholesterol(r=0.323,P=0.000),and duration of diabetes(r=0.208,P=0.004).The incidences of CAL in diabetes(96.43%),IGT(93.33%),and CHD(90.91%)was substantially higher than that in normal control(56.00%,P<0.01).The odds ratio of CAL associated with having diabetes was estimated to be 7.514(95%CI:1.885-63.778).Conclusions Coronary artery lesions are prevalent in Chinese adults with type 2 diabetes,implying a high CAD risk.EBCTA holds potential in depicting the details of CAL and can be used to track the progression of CAD in diabetes patients.

Elevated radial arterial augmentation index in hypertensive patients with diastolic dysfunction

Objective To investigate the correlation between augmentation index (AI) of the radial artery and diastolic heart function in patients with hypertension. Methods Echocardiographs were obtained for 305 patients with hypertension. AI, pulse wave velocity (PWV) of peripheral arteries and serum pro-brain natriuretic peptide (proBNP) levels were determined. Correlations and receiver operating characteristic (ROC) curves were drawn between AI values and impaired diastolic function. Results AI levels were significantly increased in patients with impaired diastolic function diagnosed by ultrasound. Assessment of diastolic heart function based on proBNP levels revealed that AI and aortic pulse wave velocity were significantly elevated in patients with impaired diastolic function. The operating curve indicated that AI may be a more accurate and efficient index for the evaluation of impaired diastolic function compared to PWV. Correlation analysis also showed that proBNP levels had altered in parallel with changes in AI and PWV. After adjusting for various factors including age, gender, blood pressure and blood lipid, a positive correlation was observed between proBNP and AI with a correlation coefficient of 0.3697 (P=0.003). However, no correlation between proBNP and aortic PWV was seen after adjustment. Conclusions Changes in radial AI levels may reflect parallel changes in diastolic cardiac function in patients with hypertension, suggesting that AI may be utilized as a non-invasive clinical indicator of diastolic heart function.

护理干预在反流性咽喉炎患者中的应用有效性及作用研究

目的 研究反流性咽喉炎(LPR)患者行综合护理干预的效果。方法 数据遴选本院2020年1月~2021年9月收治的84例LPR患者,“随机数字表法”分参照组(传统护理,n=42)、综合组(综合护理干预,n=42),2组护理效果比较分析。结果 干预前比较2组生活质量、心理情绪无差异,P>0.05;干预后与参照组比较,综合组SF-36评分更高;SAS、SDS评分更低;症状消退时间更短;综合组满意率(97.14%)高于参照组(80.00%),χ^(2)=4.480;P=0.034,P<0.05(具有统计学意义)。结论 反流性咽喉炎患者行综合护理干预可提高生活质量、改善负性情绪,减缓不适症状、提高满意度,值得推崇。