The authors report a prospective pilot trial of etanercept in corticosteroid -dependent autoimmune myasthenia gravis. Eleven patients were enrolled, with e ight completing the 6-month trial. Two patients were withdraw...The authors report a prospective pilot trial of etanercept in corticosteroid -dependent autoimmune myasthenia gravis. Eleven patients were enrolled, with e ight completing the 6-month trial. Two patients were withdrawn owing to diseas e worsening, and one patient was withdrawn because of an erythematous skin rash. Six of the eight patients who completed the trial improved, based on quantitati ve measures of muscle strength and lowering of corticosteroid requirement.展开更多
文摘The authors report a prospective pilot trial of etanercept in corticosteroid -dependent autoimmune myasthenia gravis. Eleven patients were enrolled, with e ight completing the 6-month trial. Two patients were withdrawn owing to diseas e worsening, and one patient was withdrawn because of an erythematous skin rash. Six of the eight patients who completed the trial improved, based on quantitati ve measures of muscle strength and lowering of corticosteroid requirement.