This paper is to review recent information about the relationship of calcium and dairy foods to colon cancer. The review focuses on primary prevention, discusses the potential components in dairy foods that might be a...This paper is to review recent information about the relationship of calcium and dairy foods to colon cancer. The review focuses on primary prevention, discusses the potential components in dairy foods that might be anti-neoplastic, reviews the epidemiologic information and describes intervention studies demonstrating efficacy of calcium and vitamin D in reducing colorectal polyp recurrence. Since vitamin D is important in cancer prevention, pertinent data is discussed and potential mechanisms of actions presented. Calcium and vitamin D are important agents for the primary prevention of colorectal neoplasia.展开更多
The focus of environmental regulations has changed significantly since the introduction of the bioassay as a standard means of assessing environmental impact. Prominent in this change is an increasing emphasis on prot...The focus of environmental regulations has changed significantly since the introduction of the bioassay as a standard means of assessing environmental impact. Prominent in this change is an increasing emphasis on protecting the integrity of natural ecosystems, which incorporate community- and system-level properties as well as organismal and population processes. Consequently, support for the use of multispecies testing has widened to include not only ecologists in academia but environmental scientists in the regulatory and industrial sector as well. The reason for this trend is clear: the additional environmental realism gained from tests utilizing communities of organisms allows for greater insight into the potential hazard of chemicals and other forms of human activity to natural ecosystems that cannot be obtained from single species tests alone. Many of the problems cited for multispecies testing early in their evolution as a hazard assessment tool have been refuted or overcome. In particular, the use of natural microbial communities minimizes several shortcomings typically associated with multispecies toxicity testing. This discussion includes the utility of microcosm and mesocosm tests using aquatic microbial communities as hazard assessment tools in conjunction with accumulating information on their performance in toxicity testing protocols. An increasing body of experimental evidence supports an expansion in the use of these tests for a variety of regulatory and research purposes. A shift in research focus is needed, however, to answer remaining questions and further refine standard protocols for these valuable ecotoxicological tools.展开更多
The Chinese authorities responsible for enforcing broadly drafted anti-monopoly rules governing day-to-day trading are believed to be finally gearing up to commence investigations and prosecutions. China's Anti-Mo...The Chinese authorities responsible for enforcing broadly drafted anti-monopoly rules governing day-to-day trading are believed to be finally gearing up to commence investigations and prosecutions. China's Anti-Monopoly Law(AML) commenced almost a year ago,however several'conduct rules'in the law governing fundamental business activities such as pricing,offer structures,展开更多
<p> <span style="font-family:Verdana;">Under the Nigerian privatisation programme, the issues of risk allocation and mitigation were never always properly handled. Historically, there had always ...<p> <span style="font-family:Verdana;">Under the Nigerian privatisation programme, the issues of risk allocation and mitigation were never always properly handled. Historically, there had always been a tendency to dump all the project risks on the private sector partner without properly evaluating whether it was capable of managing them. Extant literature has shown that where the comparative advantages of parties to handle risks are not properly taken into consideration, the allocation of risk is unbalanced and the tendency for the project to run into difficulties and/or fail increases. This paper looks at the electric power sector privatisation, distilling how key project risks were handled under the exercise. This should be a good pointer as to whether the privatisation exercise wo</span><span style="font-family:Verdana;">u</span><span style="font-family:Verdana;">ld be a success in the long run.</span><span></span> </p>展开更多
基金NIH grant U54-CA-100926a Clinical and Translational Science Award (UL1 RR024143) from the National Center for Research Resources
文摘This paper is to review recent information about the relationship of calcium and dairy foods to colon cancer. The review focuses on primary prevention, discusses the potential components in dairy foods that might be anti-neoplastic, reviews the epidemiologic information and describes intervention studies demonstrating efficacy of calcium and vitamin D in reducing colorectal polyp recurrence. Since vitamin D is important in cancer prevention, pertinent data is discussed and potential mechanisms of actions presented. Calcium and vitamin D are important agents for the primary prevention of colorectal neoplasia.
文摘The focus of environmental regulations has changed significantly since the introduction of the bioassay as a standard means of assessing environmental impact. Prominent in this change is an increasing emphasis on protecting the integrity of natural ecosystems, which incorporate community- and system-level properties as well as organismal and population processes. Consequently, support for the use of multispecies testing has widened to include not only ecologists in academia but environmental scientists in the regulatory and industrial sector as well. The reason for this trend is clear: the additional environmental realism gained from tests utilizing communities of organisms allows for greater insight into the potential hazard of chemicals and other forms of human activity to natural ecosystems that cannot be obtained from single species tests alone. Many of the problems cited for multispecies testing early in their evolution as a hazard assessment tool have been refuted or overcome. In particular, the use of natural microbial communities minimizes several shortcomings typically associated with multispecies toxicity testing. This discussion includes the utility of microcosm and mesocosm tests using aquatic microbial communities as hazard assessment tools in conjunction with accumulating information on their performance in toxicity testing protocols. An increasing body of experimental evidence supports an expansion in the use of these tests for a variety of regulatory and research purposes. A shift in research focus is needed, however, to answer remaining questions and further refine standard protocols for these valuable ecotoxicological tools.
文摘The Chinese authorities responsible for enforcing broadly drafted anti-monopoly rules governing day-to-day trading are believed to be finally gearing up to commence investigations and prosecutions. China's Anti-Monopoly Law(AML) commenced almost a year ago,however several'conduct rules'in the law governing fundamental business activities such as pricing,offer structures,
文摘<p> <span style="font-family:Verdana;">Under the Nigerian privatisation programme, the issues of risk allocation and mitigation were never always properly handled. Historically, there had always been a tendency to dump all the project risks on the private sector partner without properly evaluating whether it was capable of managing them. Extant literature has shown that where the comparative advantages of parties to handle risks are not properly taken into consideration, the allocation of risk is unbalanced and the tendency for the project to run into difficulties and/or fail increases. This paper looks at the electric power sector privatisation, distilling how key project risks were handled under the exercise. This should be a good pointer as to whether the privatisation exercise wo</span><span style="font-family:Verdana;">u</span><span style="font-family:Verdana;">ld be a success in the long run.</span><span></span> </p>
