Objective To study the effectiveness of percutaneous testicular sperm aspiration (PTSA) plus intracytoplasmic sperm injection (ISCI) in treating male infertility caused by azoospermia.Materials &. Methods Altogeth...Objective To study the effectiveness of percutaneous testicular sperm aspiration (PTSA) plus intracytoplasmic sperm injection (ISCI) in treating male infertility caused by azoospermia.Materials &. Methods Altogether 135 patients with azoospermia who were hospitalized in our hospital from September 1998 to December 2000 were enrolled into this study. Among the 135 patients, 71 were with obstructive azoospermia, 23 were -with congenital azoospermia, and the other 41 with idiopathic azoospermia. All these patients underwent ICSI with testicular sperm by PTSA. The fertilization rate was determined.Results The mean concentration of testicular sperm was 73. 5± 42. 59/μL and the average motility was 1. 5± 1. 17% (ranging from 1% to 5%). The motion grade of the sperm was 1. A total of 1 263 eggs were obtained and ICSI -was performed. After ICSI, 849 eggs were fertilized with a total fertilization rate of 67. 2%. In 71 patients with obstructive azoospermia, 79 cycles of ICSI were performed and the spouses of 32 patients achieved pregnancy, with a pregnancy rate of 40. 5%. In 23 patients with congenital azoospermia, 28 cycles of ICSI were performed and the spouses of 9 patients got pregnancy, having a pregnancy rate of 32. 1%. In the group of 41 patients with idiopathic azoospermia, 41 cases were given ICSI and the spouses of 8 patients got pregnancy, with a pregnancy rate of 19. 5%.Conclusion ICSI in combination with PTSA is an effective method of treating azoospermia induced male infertility, especially obstructive azoospermia.展开更多
文摘Objective To study the effectiveness of percutaneous testicular sperm aspiration (PTSA) plus intracytoplasmic sperm injection (ISCI) in treating male infertility caused by azoospermia.Materials &. Methods Altogether 135 patients with azoospermia who were hospitalized in our hospital from September 1998 to December 2000 were enrolled into this study. Among the 135 patients, 71 were with obstructive azoospermia, 23 were -with congenital azoospermia, and the other 41 with idiopathic azoospermia. All these patients underwent ICSI with testicular sperm by PTSA. The fertilization rate was determined.Results The mean concentration of testicular sperm was 73. 5± 42. 59/μL and the average motility was 1. 5± 1. 17% (ranging from 1% to 5%). The motion grade of the sperm was 1. A total of 1 263 eggs were obtained and ICSI -was performed. After ICSI, 849 eggs were fertilized with a total fertilization rate of 67. 2%. In 71 patients with obstructive azoospermia, 79 cycles of ICSI were performed and the spouses of 32 patients achieved pregnancy, with a pregnancy rate of 40. 5%. In 23 patients with congenital azoospermia, 28 cycles of ICSI were performed and the spouses of 9 patients got pregnancy, having a pregnancy rate of 32. 1%. In the group of 41 patients with idiopathic azoospermia, 41 cases were given ICSI and the spouses of 8 patients got pregnancy, with a pregnancy rate of 19. 5%.Conclusion ICSI in combination with PTSA is an effective method of treating azoospermia induced male infertility, especially obstructive azoospermia.
