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TurboID Proximity Labeling of a Protocadherin Protein to Characterize Interacting Protein Complex 被引量:1
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作者 Chenyu Wang Laidong Yu 《American Journal of Molecular Biology》 2023年第4期213-226,共14页
The study of the neuron has always been a fundamental aspect when it came to studying mental illnesses such as autism and depression. The protein protocadherin-9 (PCDH9) is an important transmembrane protein in the de... The study of the neuron has always been a fundamental aspect when it came to studying mental illnesses such as autism and depression. The protein protocadherin-9 (PCDH9) is an important transmembrane protein in the development of the neuron synapse. Hence, research on its protein interactome is key to understanding its functionality and specific properties. A newly discovered biotin ligase, TurboID, is a proximity labeler that is designed to be able to label and observe transmembrane proteins, something that previous methods struggled with. The TurboID method is verified in HEK293T cells and primary cultured mouse cortical neurons. Results have proven the validity of the TurboID method in observing PCDH9-interacting proteins. 展开更多
关键词 TurboID PCDH9 Proximity Labeling Protein Interactome Synapse Development
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The Implementation of a Communication Deadlock Analysis Based on the Theory of Deadlock Analysis for the Actor Model
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作者 Yupeng Xi Jianrui Zhang Furi Xiang 《Journal of Software Engineering and Applications》 2019年第10期393-405,共13页
We present a unique approach for communication deadlock analysis for actor-model which has an under-approximated analysis result. Our analysis detects narrowly defined communication deadlocks by finding a cyclic depen... We present a unique approach for communication deadlock analysis for actor-model which has an under-approximated analysis result. Our analysis detects narrowly defined communication deadlocks by finding a cyclic dependency relation in a novel dependency graph called the slave dependency graph. The slave dependency graph is based on a new relationship between Actors, slave dependency, defined by us. After that, we implement this theory in Soot, an analysis tool for Java, and use it to analyze actor-based Java program realized by Akka, a Java library that allows actor-based programming. We argue that our analysis can detect a specific kind of communication deadlock with the precise result, but has many limitations. 展开更多
关键词 ACTOR MODEL COMMUNICATION DEADLOCK Program ANALYSIS Akka Soot DEPENDENCY Graph
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The Different Perception and Reaction of Customers Toward Traditional Marketing and Influencer Marketing in Food
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作者 REN Qingyang ZHOU Lin LIU Fengyang 《Management Studies》 2022年第2期94-105,共12页
This research paper is aimed at investigating the consumer preference for traditional marketing and influencer marketing in food industry.To accomplish this,the researchers set two questionnaire surveys to collect dat... This research paper is aimed at investigating the consumer preference for traditional marketing and influencer marketing in food industry.To accomplish this,the researchers set two questionnaire surveys to collect data.These two questionnaires investigated consumers’different attitudes and reaction toward two rose-cake brands(Holiland and LI ZI QI),by showing them the two different types of advertisements:one for traditional marketing and the other for influencer marketing.After a detailed analysis of the data collected,it was discovered that both influencer marketing and traditional marketing have the capability to deliver the persuasive product information and make consumers desirable to purchase the products;however,consumers tend to pay more creditably and trust to LI ZI QI’s brand,which is the brand using influencer marketing,and are willing to spend more money on it. 展开更多
关键词 influencer marketing traditional marketing food industry questionnaire survey
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Interaction between Gut Microbiota and Medicinal Food Homology in Depression
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作者 Tian Yu 《Journal of Biosciences and Medicines》 2024年第11期190-205,共16页
Depression can be counted as the most severe mental disease in the world nowadays, which lacks effective curing treatments. With an increasing number of patients, developing effective treatments with fewer side effect... Depression can be counted as the most severe mental disease in the world nowadays, which lacks effective curing treatments. With an increasing number of patients, developing effective treatments with fewer side effects is essential. Medicinal food homology has been proven to influence the pathogenesis of depression positively. Gut microbiota plays a vital role in exerting the antidepressant effect of substances from the medicinal food homology, as they facilitate different chemical processes and increase the bioavailability of the substances. This review summarizes the correlation between gut microbiota and depression and provides new pathways for effective treatments of depression. 展开更多
关键词 Medicinal Food Homology Gut Microbiota Depression Antidepressant Pathogenesis
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