This paper comprehensively analyses the first-ever monkeypox outbreak in Shenzhen,China,encompassing clinical symptomatology,therapeutic approaches,epidemiological research,and comprehensive laboratory tests,aiming to...This paper comprehensively analyses the first-ever monkeypox outbreak in Shenzhen,China,encompassing clinical symptomatology,therapeutic approaches,epidemiological research,and comprehensive laboratory tests,aiming to establish a robust reference for future monkeypox mitigation and management strategies.The investigation involved a thorough investigation of all identified positive cases,including extensive molecular analysis by nucleic acid detection and whole-genome sequencing of the monkeypox virus.Contact tracing and containment of the infected individuals were also undertaken.Three distinct monkeypox cases were identified in this unique outbreak,exhibiting mild and atypical clinical manifestations,primarily fever and rash.All cases were associated with a single transmission chain,primarily facilitated through close contact and homosexual behavior,indicative of a high-risk factor for monkeypox transmission.展开更多
Summary What is already known about this topic?Dichloromethane(DCM)is a colorless and transparent organic solvent that commonly causes poisoning during occupational contact.What is added by this report?Unknown to teac...Summary What is already known about this topic?Dichloromethane(DCM)is a colorless and transparent organic solvent that commonly causes poisoning during occupational contact.What is added by this report?Unknown to teachers and students,they were utilizing an acrylic paint cleaner that contained DCM.At the time of the poisoning incident,the art room was occupied beyond its capacity with inadequate local ventilation.The primary cause of the incident was determined to be the students’inhalation of DCM during the cleaning process.What are the implications for public health practice?The unclear composition of environmental cleaning products available for purchase online presents a major obstacle for consumers trying to assess their toxicity.It is imperative that robust regulatory measures and proactive public education campaigns are implemented to mitigate instances of poisoning.展开更多
基金the Science and Technology Planning Project of Guangdong Province of China(Grant 2021 B1212030009)Sanming Project of Medicine in Shenzhen(No.SZSM202011008)+1 种基金Research Foundation of Shenzhen Science and Technology Emergency Key Technology Program(JSGG20220301090007009)Shenzhen Key Medical Discipline Construction Fund(SZXK064).
文摘This paper comprehensively analyses the first-ever monkeypox outbreak in Shenzhen,China,encompassing clinical symptomatology,therapeutic approaches,epidemiological research,and comprehensive laboratory tests,aiming to establish a robust reference for future monkeypox mitigation and management strategies.The investigation involved a thorough investigation of all identified positive cases,including extensive molecular analysis by nucleic acid detection and whole-genome sequencing of the monkeypox virus.Contact tracing and containment of the infected individuals were also undertaken.Three distinct monkeypox cases were identified in this unique outbreak,exhibiting mild and atypical clinical manifestations,primarily fever and rash.All cases were associated with a single transmission chain,primarily facilitated through close contact and homosexual behavior,indicative of a high-risk factor for monkeypox transmission.
基金Supported by Shenzhen Fundamental Research Program(No.JCYJ20220531091213031).
文摘Summary What is already known about this topic?Dichloromethane(DCM)is a colorless and transparent organic solvent that commonly causes poisoning during occupational contact.What is added by this report?Unknown to teachers and students,they were utilizing an acrylic paint cleaner that contained DCM.At the time of the poisoning incident,the art room was occupied beyond its capacity with inadequate local ventilation.The primary cause of the incident was determined to be the students’inhalation of DCM during the cleaning process.What are the implications for public health practice?The unclear composition of environmental cleaning products available for purchase online presents a major obstacle for consumers trying to assess their toxicity.It is imperative that robust regulatory measures and proactive public education campaigns are implemented to mitigate instances of poisoning.
