Sixteen resveratrol analogs（stilbene derivatives） including resveratrol were synthesized, in which hy- droxystilbenes, naturally occurring polyphenols, showed protective effects against reactive oxygen and nitrogen ...Sixteen resveratrol analogs（stilbene derivatives） including resveratrol were synthesized, in which hy- droxystilbenes, naturally occurring polyphenols, showed protective effects against reactive oxygen and nitrogen spe- cies（ROS/RNS） and hexahydroxystilbene（16） displayed the strongest activities against NO and l,l-diphenyl- 2-picrylhydrazyl（DPPH） with IC5o values of 7.8 and 5.7 μmol/L, respectively.展开更多
基金Supported by the Shenzhen Science and Technology Program, China（No.JCYJ20120830153011458）, the Project of the Edu- cational Commission of Guangdong Province of China（No.2013KJCX0164） and the Natural Science Foundation of Shenzhen Universitiy, China（No.00036159）.
文摘Sixteen resveratrol analogs（stilbene derivatives） including resveratrol were synthesized, in which hy- droxystilbenes, naturally occurring polyphenols, showed protective effects against reactive oxygen and nitrogen spe- cies（ROS/RNS） and hexahydroxystilbene（16） displayed the strongest activities against NO and l,l-diphenyl- 2-picrylhydrazyl（DPPH） with IC5o values of 7.8 and 5.7 μmol/L, respectively.
