Single-cell and spatial-omic technologies are providing unprecedented detail into the molecular principles underlying a wide range of developmental and disease contexts.These observations are substantially deepening m...Single-cell and spatial-omic technologies are providing unprecedented detail into the molecular principles underlying a wide range of developmental and disease contexts.These observations are substantially deepening many areas of biological research.However,despite the increasing application of these techniques to biological problems we are only revealing the tip of the iceberg,and there exist large gaps in our understanding of the behavior of single cells in vitro and in vivo that need to be filled.Additionally,the development of robust analytical tools and meta-analysis of existing data lag behind the rapid generation of new data.展开更多
文摘Single-cell and spatial-omic technologies are providing unprecedented detail into the molecular principles underlying a wide range of developmental and disease contexts.These observations are substantially deepening many areas of biological research.However,despite the increasing application of these techniques to biological problems we are only revealing the tip of the iceberg,and there exist large gaps in our understanding of the behavior of single cells in vitro and in vivo that need to be filled.Additionally,the development of robust analytical tools and meta-analysis of existing data lag behind the rapid generation of new data.