With the rapid development of information and communication technology,a key objective in the field of optoelectronic integrated devices is to reduce the nano-laser size and energy consumption.Photonics nanolasers are...With the rapid development of information and communication technology,a key objective in the field of optoelectronic integrated devices is to reduce the nano-laser size and energy consumption.Photonics nanolasers are unable to exceed the diffraction limit and typically exhibit low modulation rates of several GHz.In contrast,plasmonic nanolaser utilizes highly confined surface plasmon polariton(SPP)mode that can exceed diffraction limit and their strong Purcell effect can accelerate the modulation rates to several THz.Herein,we propose a parametrically tunable artificial plasmonic nanolasers based on metal–insulator–semiconductor–insulator–metal(MISIM)structure,which demonstrates its ability to compress the mode field volume toλ/14.As the pump power increases,the proposed artificial plasmonic nanolaser exhibits 20-nm-wide output spectrum.Additionally,we investigate the effects of various cavity parameters on the nanolaser’s output threshold,offering potentials for realizing low-threshold artificial plasmonic nanolasers.Moreover,we observe a blue shift in the center wavelength of the nanolaser output with thinner gain layer thickness,predominantly attributed to the increased exciton–photon coupling strength.Our work brings inspiration to several areas,including spaser-based interconnects,nano-LEDs,spontaneous emission control,miniaturization of photon condensates,eigenmode engineering of plasmonic nanolasers,and optimal design driven by artificial intelligence(AI).展开更多
Two cardiac functional models are constructed in this paper. One is a single current model and the other is a current multipole model. Parameters denoting the properties of these two models are calculated by a least-s...Two cardiac functional models are constructed in this paper. One is a single current model and the other is a current multipole model. Parameters denoting the properties of these two models are calculated by a least-square fit to the measurements using a simulated annealing algorithm. The measured signals are detected at 36 observation nodes by a superconducting quantum interference device (SQUID). By studying the trends of position, orientation and magnitude of the single current dipole model and the current multipole model in the QRS complex during one time span and comparing the reconstructed magnetocardiography (MCG) of these two cardiac models, we find that the current multipole model is a more appropriate model to represent cardiac electrophysiological activity.展开更多
The pore structure of sandstone in an oil reservoir is investigated using atomic force microscopy(AFM).At nanoscale resolution,AFM images of sandstone show us the fine structure.The real height data of images display ...The pore structure of sandstone in an oil reservoir is investigated using atomic force microscopy(AFM).At nanoscale resolution,AFM images of sandstone show us the fine structure.The real height data of images display the three-dimensional space structure of sandstone effectively.The three-dimensional analysis results show that the AFM images of sandstone have unique characteristics that,like fingerprints,can identify different structural properties of sandstones.The results demonstrate that AFM is an effective method used to represent original sandstone in petroleum reservoirs,and may help geologists to appreciate the sandstone in oil reservoirs fully.展开更多
After a brief review on the progresses in GaN substrates by ammonothermal method and Na-flux method and hydride vapor phase epitaxy (HVPE) technology, our research results of growing GaN thick layer by a gas fow-rno...After a brief review on the progresses in GaN substrates by ammonothermal method and Na-flux method and hydride vapor phase epitaxy (HVPE) technology, our research results of growing GaN thick layer by a gas fow-rnodulated HVPE, removing the GaN layer through an efficient self-separation process from sapphire substrate, and modifying the uniformity of multiple wafer growth are presented. The effects of surface morphology and defect behaviors on the GaN homo-epitaxial growth on free standing substrate are also discussed, and followed by the advances of LEDs on GaN substrates and prospects of their applications in solid state lighting.展开更多
We describe the fabrication of high performance YBa2Cu3O7-δ (YBCO) radio frequency (RF) superconducting quantum interference devices (SQUIDs), which were prepared on 5 mm×5 mm LaAlO3 (LAO) substrates by ...We describe the fabrication of high performance YBa2Cu3O7-δ (YBCO) radio frequency (RF) superconducting quantum interference devices (SQUIDs), which were prepared on 5 mm×5 mm LaAlO3 (LAO) substrates by employing stepedge junctions (SEJs) and in flip-chip configuration with 12 mm×12 mm resonators. The step in the substrate was produced by Ar ion etching with step angles ranging from 47° to 61°, which is steep enough to ensure the formation of grain boundaries (GBs) at the step edges. The YBCO film was deposited using the pulsed laser deposition (PLD) technique with a film thickness half of the height of the substrate step. The inductance of the SQUID washer was designed to be about 157 pH. Under these circumstances, high performance YBCO RF SQUIDs were successfully fabricated with a typical flux-voltage transfer ratio of 83 mV/φ0, a white flux noise of 29 μφ0/√Hz, and the magnetic field sensitivity as high as 80 fT/√Hz. These devices have been applied in magnetocardiography and geological surveys.展开更多
This paper discusses the forward and inverse problem for cardiac magnetic fields and electric potentials. A torso-heart model established by boundary element method (BEM) is used for studying the distributions of ca...This paper discusses the forward and inverse problem for cardiac magnetic fields and electric potentials. A torso-heart model established by boundary element method (BEM) is used for studying the distributions of cardiac magnetic fields and electric potentials. Because node-to-node and triangle-to-triangle BEM can lead to discrepant field distributions, their properties and influences are compared. Then based on constructed torso-heart model and supposed current source functional model-current dipole array, the magnetic and electric imaging by optimal constrained linear inverse method are applied at the same time. Through figure and reconstructing parameter comparison, though the magnetic current dipole array imaging possesses better reconstructing effect, however node-to-node BEM and triangleto-triangle BEM make little difference to magnetic and electric imaging.展开更多
This paper constructs a concentric ellipsoid torso-heart model by boundary element method and investigates the impacts of model structures on the cardiac magnetic fields generated by both equivalent primary source--a ...This paper constructs a concentric ellipsoid torso-heart model by boundary element method and investigates the impacts of model structures on the cardiac magnetic fields generated by both equivalent primary source--a current dipole and volume currents. Then by using the simulated magnetic fields based on torso-heart model as input, the cardiac current sources--an array of current dipoles by optimal constrained linear inverse method are constructed. Next, the current dipole array reconstruction considering boundaries is compared with that in an unbounded homogeneous medium. Furthermore, the influence of random noise on reconstruction is also considered and the reconstructing effect is judged by several reconstructing parameters.展开更多
A typical biological cell lives in a small volmne at room temperature; the noise effect on the cell signal transduction pathway may play an important role in its dynamics. Here, using the transforming growth factor-β...A typical biological cell lives in a small volmne at room temperature; the noise effect on the cell signal transduction pathway may play an important role in its dynamics. Here, using the transforming growth factor-β signal transduction pathway as an example, we report our stochastic simulations of the dynamics of the pathway and introduce a linear noise approximation method to calculate the transient intrinsic noise of pathway components. We compare the numerical solutions of the linear noise approximation with the statistic results of chemical Langevin equations, and find that they are quantitatively in agreement with the other. When transforming growth factor-β dose decreases to a low level, the time evolution of noise fluctuation of nuclear Smad2-Smad4 complex indicates the abnormal enhancement in the transient signal activation process.展开更多
The vast majority of high-performance perovskite solar cells(PSCs) are based on a formamidinium lead iodide(FAPbI_(3))-dominant composition. Nevertheless, the FA-based perovskite films suffer from undesirable phase tr...The vast majority of high-performance perovskite solar cells(PSCs) are based on a formamidinium lead iodide(FAPbI_(3))-dominant composition. Nevertheless, the FA-based perovskite films suffer from undesirable phase transition and defects-induced non-ideal interfacial recombination, which significantly induces energy loss and hinders the improvement of device performance. Herein, we employed 4-fluorophenylmethylammonium iodide(F-PMAI) to modulate surface structure and energy level alignment of the FA-based perovskite films. The superior optoelectronic films were obtained with reduced trap density, pure α-phase FAPbI_(3) and favorable energy band bending. The lifetime of photogenerated charge carriers increased from 489.3 ns to 1010.6 ns, and a more “p-type” perovskite film was obtained by the post-treatment with F-PMAI. Following this strategy, we demonstrated an improved power conversion efficiency of 22.59% for the FA-based PSCs with an open-circuit voltage loss of 399 m V.展开更多
Chirality plays an important role in biological processes,and enantiomers often possess similar physical properties and different physiologic functions.In recent years,chiral detection of enantiomers become a popular ...Chirality plays an important role in biological processes,and enantiomers often possess similar physical properties and different physiologic functions.In recent years,chiral detection of enantiomers become a popular topic.Plasmonic metasurfaces enhance weak inherent chiral effects of biomolecules,so they are used in chiral detection.Artificial intelligence algorithm makes a lot of contribution to many aspects of nanophotonics.Here,we propose a nanostructure design method based on reinforcement learning and devise chiral nanostructures to distinguish enantiomers.The algorithm finds out the metallic nanostructures with a sharp peak in circular dichroism spectra and emphasizes the frequency shifts caused by nearfield interaction of nanostructures and biomolecules.Our work inspires universal and efficient machine-learning methods for nanophotonic design.展开更多
Proton transfer(PT) is a process of fundamental importance in hydrogen(H)-bonded systems. At cryogenic or moderate temperatures, pronounced quantum tunneling may happen due to the light mass of H. Single PT processes ...Proton transfer(PT) is a process of fundamental importance in hydrogen(H)-bonded systems. At cryogenic or moderate temperatures, pronounced quantum tunneling may happen due to the light mass of H. Single PT processes have been extensively studied. However, for PT involving multiple protons, our understanding remains in its infancy stage due to the complicated interplay between the high-dimensional nature of the process and the quantum nature of tunneling. Cyclic H-bonded systems are typical examples of this, where PT can happen separately via a “stepwise” mechanism or collectively via a “concerted” mechanism. In the first scenario, some protons hop first, typically resulting in metastable intermediate states(ISs) and the reaction pathway passes through multiple transition states. Whilst in the concerted mechanism, all protons move simultaneously, resulting in only one barrier along the path. Here, we review previous experimental and theoretical studies probing quantum tunneling in several representative systems for cyclic PT, with more focus on recent theoretical findings with path-integral based methods. For gas-phase porphyrin and porphycene, as well as porphycene on a metal surface, theoretical predictions are consistent with experimental observations, and enhance our understanding of the processes. Yet, discrepancies in the PT kinetic isotope effects between experiment and theory appear in two systems,most noticeably in water tetramer adsorbed on NaCl(001) surface, and also hinted in porphycene adsorbed on Ag(110)surface. In ice Ih, controversy surrounding concerted PT remains even between experiments. Despite of the recent progress in both theoretical methods and experimental techniques, multiple PT processes in cyclic H-bonded systems remain to be mysterious.展开更多
Cardiovascular diseases(CVDs)are a leading factor driving mortality worldwide.Iron,an essential trace mineral,is important in numerous biological processes,and its role in CVDs has raised broad discussion for decades....Cardiovascular diseases(CVDs)are a leading factor driving mortality worldwide.Iron,an essential trace mineral,is important in numerous biological processes,and its role in CVDs has raised broad discussion for decades.Iron-mediated cell death,namely ferroptosis,has attracted much attention due to its critical role in cardiomyocyte damage and CVDs.Furthermore,ferritinophagy is the upstream mechanism that induces ferroptosis,and is closely related to CVDs.This review aims to delineate the processes and mechanisms of ferroptosis and ferritinophagy,and the regulatory pathways and molecular targets involved in ferritinophagy,and to determine their roles in CVDs.Furthermore,we discuss the possibility of targeting ferritinophagy-induced ferroptosis modulators for treating CVDs.Collectively,this review offers some new insights into the pathology of CVDs and identifies possible therapeutic targets.展开更多
Josephson junction plays a key role not only in studying the basic physics of unconventional iron-based superconductors but also in realizing practical application of thin-film based devices,therefore the preparation ...Josephson junction plays a key role not only in studying the basic physics of unconventional iron-based superconductors but also in realizing practical application of thin-film based devices,therefore the preparation of high-quality iron pnictide Josephson junctions is of great importance.In this work,we have successfully fabricated Josephson junctions from Co-doped BaFe_(2)As_(2)thin films using a direct junction fabrication technique which utilizes high energy focused helium ion beam(FHIB).The electrical transport properties were investigated for junctions fabricated with various He^(+)irradiation doses.The junctions show sharp superconducting transition around 24 K with a narrow transition width of 2.5 K,and a dose correlated foot-structure resistance which corresponds to the effective tuning of junction properties by He^(+)irradiation.Significant J_c suppression by more than two orders of magnitude can be achieved by increasing the He^(+)irradiation dose,which is advantageous for the realization of low noise ion pnictide thin film devices.Clear Shapiro steps are observed under 10 GHz microwave irradiation.The above results demonstrate the successful fabrication of high quality and controllable Co-doped BaFe_(2)As_(2)Josephson junction with high reproducibility using the FHIB technique,laying the foundation for future investigating the mechanism of iron-based superconductors,and also the further implementation in various superconducting electronic devices.展开更多
Nanoscale permanent magnetic materials,which possess excellent magnetic and mechanical properties,thermal stability,and corrosion resistance,have become a research hotspot for permanent magnets.In reality,however,the ...Nanoscale permanent magnetic materials,which possess excellent magnetic and mechanical properties,thermal stability,and corrosion resistance,have become a research hotspot for permanent magnets.In reality,however,the obtained maximum energy product,(BH)max,is not satisfactory in comparison with the theory limit,especially for exchange-coupled nanocomposite magnets.The construction of an ideal microstructure still remains a challenge in the synthesis and preparation of nanoscale permanent magnets.This work reported the impact of rapid thermal process(RTP)with electron-beam heating on the microstructures of Nd12.5-xFe80.8+xB6.2Nb0.2Ga0.3(x=0,2.5)nanocomposites.It was found that the crystallization time was greatly reduced,from 15 min under the conventional annealing conditions to 0.1 s under the RTP.For Nd2Fe14B single-phase materials,the crystallization temperature of the RTP ribbons decreased by about 248 C compared with that of the ribbons produced by the conventional annealing method.A synergetic crystallization of the Nd2Fe14B and a-Fe phases was observed under the RTP,which restrained not only the shape,size distribution,and compositions of the hard and the soft phases,but also the interface between them.This modification effect became more obvious as the fraction of Fe increased.Due to the improvement in the uniformity of the Nd2Fe14B and a-Fe phases,and their grain size distribution,better magnetic properties were achieved using RTP in comparison with the conventional annealing method.展开更多
In this paper, we present a magnetocardiogram (MCG) simulation study using the boundary element method (BEM) and based on the virtual heart model and the realistic human volume conductor model. The different contr...In this paper, we present a magnetocardiogram (MCG) simulation study using the boundary element method (BEM) and based on the virtual heart model and the realistic human volume conductor model. The different contributions of cardiac equivalent source models and volume conductor models to the MCG are deeply and comprehensively investigated. The single dipole source model, the multiple dipoles source model and the equivalent double layer (EDL) source model are analysed and compared with the cardiac equivalent source models. Meanwhile, the effect of the volume conductor model on the MCG combined with these cardiac equivalent sources is investigated. The simulation results demonstrate that the cardiac electrophysiological information will be partly missed when only the single dipole source is taken, while the EDL source is a good option for MCG simulation and the effect of the volume conductor is smallest for the EDL source. Therefore, the EDL source is suitable for the study of MCG forward and inverse problems, and more attention should be paid to it in future MCG studies.展开更多
Integrated circuit(IC)industry has fully considered the fact that the Moore’s Law is slowing down or ending.Alternative solutions are highly and urgently desired to break the physical size limits in the More-than-Moo...Integrated circuit(IC)industry has fully considered the fact that the Moore’s Law is slowing down or ending.Alternative solutions are highly and urgently desired to break the physical size limits in the More-than-Moore era.Integrated silicon photonics technology exhibits distinguished potential to achieve faster operation speed,less power dissipation,and lower cost in IC industry,because their COMS compatibility,fast response,and high monolithic integration capability.Particularly,compared with other on-chip resonators(e.g.microrings,2D photonic crystal cavities)silicon-on-insulator(SOI)-based photonic crystal nanobeam cavity(PCNC)has emerged as a promising platform for on-chip integration,due to their attractive properties of ultra-high Q/V,ultra-compact footprints and convenient integration with silicon bus-waveguides.In this paper,we present a comprehensive review on recent progress of on-chip PCNC devices for lasing,modulation,switching/filting and label-free sensing,etc.展开更多
Two groups of coated conductor samples with different thicknesses of CeO2 cap layers deposited by pulsed laser deposition (PLD) under the same conditions have been studied. Of them, one group is of CeO2 films, which...Two groups of coated conductor samples with different thicknesses of CeO2 cap layers deposited by pulsed laser deposition (PLD) under the same conditions have been studied. Of them, one group is of CeO2 films, which are deposited on stainless steel (SS) tapes coated by IBAD-YSZ (IBAD-YSZ/SS), and the other group is of CeO2/YSZ/Y2O3 multilayers, which are deposited on NiW substrates by PLD for the fabrication of YBCO-coated conductor through the RABiTS approach. YBCO film is then deposited on the tops of both types of buffer layers by PLD. The effects of the thickness of the CeO2 film on the texture of the CeO2 film and the critical current density (Jc) of the YBCO film are analysed. For the case of CeO2 film on IBAD-YSZ/SS, there appears a self-epitaxy effect with increasing thickness of the CeO2 film. For CeO2/YSZ/Y2O3/NiW, in which the buffer layers are deposited by PLD, there occurs no self-epitaxy effect, and the optimal thickness of CeO2 is about 50 nm. The surface morphologies of the two groups of samples are examined by SEM.展开更多
A cardiac vector model is presented and verified, and then the forward problem for cardiac magnetic fields and electric potential are discussed based on this model and the realistic human torso volume conductor model,...A cardiac vector model is presented and verified, and then the forward problem for cardiac magnetic fields and electric potential are discussed based on this model and the realistic human torso volume conductor model, including lungs. A torso-cardiac vector model is used for a 12-lead electrocardiographic (ECG) and magneto-cardiogram (MCG) simulation study by using the boundary element method (BEM). Also, we obtain the MCG wave picture using a compound four-channel HTc.SQUID system in a magnetically shielded room. By comparing the simulated results and experimental results, we verify the cardiac vector model and then do a preliminary study of the forward problem of MCG and ECG. Therefore, the results show that the vector model is reasonable in cardiac electrophysiology.展开更多
In order to eliminate the influence of the large-amplitude magnetic field noise that has complicated magnetocardio- graphic studies since October 2009, we have performed high-accuracy measurement of the environmental ...In order to eliminate the influence of the large-amplitude magnetic field noise that has complicated magnetocardio- graphic studies since October 2009, we have performed high-accuracy measurement of the environmental magnetic field noise in the vicinity of Beijing Subway Line 4 using a three-component height Tc radio frequency (rf) superconducting quantum interference device (SQUID). By analysing the spatial form and other characteristics of the time and the fre- quency domains and by calculating the circumferential magnetic field distribution based on a duel-end feeding system model, we reach the following conclusions: (i) the main source of magnetic field noise is the magnetic field generated by thel subway trains, and (ii) the magnetic field interference results mainly from the imbalance between traction current and return rail current that is caused by the leakage current.展开更多
Since the successful fabrication of two-dimensional (2D) ferromagnetic (FM) monolayer CrI3 and Cr2Ge2Te6, 2D FM materials are becoming an exciting research topic in condensed matter physics and materials fields, as th...Since the successful fabrication of two-dimensional (2D) ferromagnetic (FM) monolayer CrI3 and Cr2Ge2Te6, 2D FM materials are becoming an exciting research topic in condensed matter physics and materials fields, as they provide a good platform to explore the fundamental physical properties of magnetic materials under 2D limit. In this review, we summarize the theoretical research progress of intrinsic 2D FM materials and related van der Waals heterostructures (vdWHs) including their electronic structures, magnetism, Curie temperature, valley polarization, and band alignment. Moreover, we also summarize recent researches on the methods that used to regulate the above properties of 2D FM materials and vdWHs, such as defects, doping, strain, electric field and interlayer coupling. These studies show that 2D FM materials have broad application prospects in spintronics and valleytronics. However, there are still many problems waiting to be solved on the way to practical application.展开更多
基金Project supported by the National Natural Science Foundation of China(Grant Nos.12174037,12204061,12204030,and 62375003)the Fundamental Research Funds for the Central Universities,China(Grant No.2022XD-A09)the Fund from the State Key Laboratory of Information Photonics and Optical Communication,China(Grant No.IPOC2021ZZ02)。
文摘With the rapid development of information and communication technology,a key objective in the field of optoelectronic integrated devices is to reduce the nano-laser size and energy consumption.Photonics nanolasers are unable to exceed the diffraction limit and typically exhibit low modulation rates of several GHz.In contrast,plasmonic nanolaser utilizes highly confined surface plasmon polariton(SPP)mode that can exceed diffraction limit and their strong Purcell effect can accelerate the modulation rates to several THz.Herein,we propose a parametrically tunable artificial plasmonic nanolasers based on metal–insulator–semiconductor–insulator–metal(MISIM)structure,which demonstrates its ability to compress the mode field volume toλ/14.As the pump power increases,the proposed artificial plasmonic nanolaser exhibits 20-nm-wide output spectrum.Additionally,we investigate the effects of various cavity parameters on the nanolaser’s output threshold,offering potentials for realizing low-threshold artificial plasmonic nanolasers.Moreover,we observe a blue shift in the center wavelength of the nanolaser output with thinner gain layer thickness,predominantly attributed to the increased exciton–photon coupling strength.Our work brings inspiration to several areas,including spaser-based interconnects,nano-LEDs,spontaneous emission control,miniaturization of photon condensates,eigenmode engineering of plasmonic nanolasers,and optimal design driven by artificial intelligence(AI).
基金Project supported by the State Key Development Program for Basic Research of China (Grant No 2006CB601007)the National Natural Science Foundation of China (Grant No 10674006)the National High Technology Research and Development Program of China (Grant No 2007AA03Z238)
文摘Two cardiac functional models are constructed in this paper. One is a single current model and the other is a current multipole model. Parameters denoting the properties of these two models are calculated by a least-square fit to the measurements using a simulated annealing algorithm. The measured signals are detected at 36 observation nodes by a superconducting quantum interference device (SQUID). By studying the trends of position, orientation and magnitude of the single current dipole model and the current multipole model in the QRS complex during one time span and comparing the reconstructed magnetocardiography (MCG) of these two cardiac models, we find that the current multipole model is a more appropriate model to represent cardiac electrophysiological activity.
基金by the Educational Commission of Heilongjiang Province(No 11551024)Daqing Oilfield Limited Company of China under Grant No DQYT-2010-JS-242.
文摘The pore structure of sandstone in an oil reservoir is investigated using atomic force microscopy(AFM).At nanoscale resolution,AFM images of sandstone show us the fine structure.The real height data of images display the three-dimensional space structure of sandstone effectively.The three-dimensional analysis results show that the AFM images of sandstone have unique characteristics that,like fingerprints,can identify different structural properties of sandstones.The results demonstrate that AFM is an effective method used to represent original sandstone in petroleum reservoirs,and may help geologists to appreciate the sandstone in oil reservoirs fully.
基金Project supported by the National High Technology Research and Development Program of China(Grant No.2014AA032605)the National Key Basic Research and Development Program of China(Grant Nos.2012CB619304 and 2011CB301904)the National Natural Science Foundation of China(Grant Nos.61376012,61474003,and 61327801)
文摘After a brief review on the progresses in GaN substrates by ammonothermal method and Na-flux method and hydride vapor phase epitaxy (HVPE) technology, our research results of growing GaN thick layer by a gas fow-rnodulated HVPE, removing the GaN layer through an efficient self-separation process from sapphire substrate, and modifying the uniformity of multiple wafer growth are presented. The effects of surface morphology and defect behaviors on the GaN homo-epitaxial growth on free standing substrate are also discussed, and followed by the advances of LEDs on GaN substrates and prospects of their applications in solid state lighting.
基金supported by the National Basic Research Program of China(Grant No.2011CBA00106)the National Natural Science Foundation of China(Grant No.11074008)the Research Fund for the Doctoral Program of Higher Education,China(Grant No.20100001120006)
文摘We describe the fabrication of high performance YBa2Cu3O7-δ (YBCO) radio frequency (RF) superconducting quantum interference devices (SQUIDs), which were prepared on 5 mm×5 mm LaAlO3 (LAO) substrates by employing stepedge junctions (SEJs) and in flip-chip configuration with 12 mm×12 mm resonators. The step in the substrate was produced by Ar ion etching with step angles ranging from 47° to 61°, which is steep enough to ensure the formation of grain boundaries (GBs) at the step edges. The YBCO film was deposited using the pulsed laser deposition (PLD) technique with a film thickness half of the height of the substrate step. The inductance of the SQUID washer was designed to be about 157 pH. Under these circumstances, high performance YBCO RF SQUIDs were successfully fabricated with a typical flux-voltage transfer ratio of 83 mV/φ0, a white flux noise of 29 μφ0/√Hz, and the magnetic field sensitivity as high as 80 fT/√Hz. These devices have been applied in magnetocardiography and geological surveys.
基金Project supported by the State Key Development Program for Basic Research of China (Grant No. 2006CB601007)the National Natural Science Foundation of China (Grant No. 10674006)the National High Technology Research and Development Program of China (Grant No. 2007AA03Z238)
文摘This paper discusses the forward and inverse problem for cardiac magnetic fields and electric potentials. A torso-heart model established by boundary element method (BEM) is used for studying the distributions of cardiac magnetic fields and electric potentials. Because node-to-node and triangle-to-triangle BEM can lead to discrepant field distributions, their properties and influences are compared. Then based on constructed torso-heart model and supposed current source functional model-current dipole array, the magnetic and electric imaging by optimal constrained linear inverse method are applied at the same time. Through figure and reconstructing parameter comparison, though the magnetic current dipole array imaging possesses better reconstructing effect, however node-to-node BEM and triangleto-triangle BEM make little difference to magnetic and electric imaging.
基金Project supported by the State Key Development Program for Basic Research of China(Grant No.2006CB601007)the National Natural Science Foundation of China(Grant No.10674006)the National High Technology Research and Development Program of China(Grant No.2007AA03Z238)
文摘This paper constructs a concentric ellipsoid torso-heart model by boundary element method and investigates the impacts of model structures on the cardiac magnetic fields generated by both equivalent primary source--a current dipole and volume currents. Then by using the simulated magnetic fields based on torso-heart model as input, the cardiac current sources--an array of current dipoles by optimal constrained linear inverse method are constructed. Next, the current dipole array reconstruction considering boundaries is compared with that in an unbounded homogeneous medium. Furthermore, the influence of random noise on reconstruction is also considered and the reconstructing effect is judged by several reconstructing parameters.
基金Project supported by the National Natural Science Foundation of China (Grant No. 10721403)the National Basic Research Program of China (Grant No. 2009CB918500)
文摘A typical biological cell lives in a small volmne at room temperature; the noise effect on the cell signal transduction pathway may play an important role in its dynamics. Here, using the transforming growth factor-β signal transduction pathway as an example, we report our stochastic simulations of the dynamics of the pathway and introduce a linear noise approximation method to calculate the transient intrinsic noise of pathway components. We compare the numerical solutions of the linear noise approximation with the statistic results of chemical Langevin equations, and find that they are quantitatively in agreement with the other. When transforming growth factor-β dose decreases to a low level, the time evolution of noise fluctuation of nuclear Smad2-Smad4 complex indicates the abnormal enhancement in the transient signal activation process.
基金funded by the National Natural Science Foundation of China(62004165)the China Postdoctoral Science Foundation(2020M670036)+2 种基金the Natural Science Foundation of Shaanxi Province,China(2020JQ195)the Joint Research Funds of Department of Science&Technology of Shaanxi Province and Northwestern Polytechnical University(2020GXLH-Z-007,2020GXLH-Z-025)the Fundamental Research Funds for the Central Universities。
文摘The vast majority of high-performance perovskite solar cells(PSCs) are based on a formamidinium lead iodide(FAPbI_(3))-dominant composition. Nevertheless, the FA-based perovskite films suffer from undesirable phase transition and defects-induced non-ideal interfacial recombination, which significantly induces energy loss and hinders the improvement of device performance. Herein, we employed 4-fluorophenylmethylammonium iodide(F-PMAI) to modulate surface structure and energy level alignment of the FA-based perovskite films. The superior optoelectronic films were obtained with reduced trap density, pure α-phase FAPbI_(3) and favorable energy band bending. The lifetime of photogenerated charge carriers increased from 489.3 ns to 1010.6 ns, and a more “p-type” perovskite film was obtained by the post-treatment with F-PMAI. Following this strategy, we demonstrated an improved power conversion efficiency of 22.59% for the FA-based PSCs with an open-circuit voltage loss of 399 m V.
基金This work is supported by the National Science Foundation of China(Grant Nos.12027807,62225501,and 11974002)National Key Research and Development Program of China(Grant No.2020YFA0211300,2020YFA0906900,and 2021YFF1200500)PKU-Baidu Fund Project(Grant No.2020BD023),and High-performance Computing Platform of Peking University.
文摘Chirality plays an important role in biological processes,and enantiomers often possess similar physical properties and different physiologic functions.In recent years,chiral detection of enantiomers become a popular topic.Plasmonic metasurfaces enhance weak inherent chiral effects of biomolecules,so they are used in chiral detection.Artificial intelligence algorithm makes a lot of contribution to many aspects of nanophotonics.Here,we propose a nanostructure design method based on reinforcement learning and devise chiral nanostructures to distinguish enantiomers.The algorithm finds out the metallic nanostructures with a sharp peak in circular dichroism spectra and emphasizes the frequency shifts caused by nearfield interaction of nanostructures and biomolecules.Our work inspires universal and efficient machine-learning methods for nanophotonic design.
基金Project supported by the National Basic Research Programs of China (Grant No.2021YFA1400503)the National Natural Science Foundation of China (Grant No.11934003)+1 种基金the Beijing Natural Science Foundation (Grant No.Z200004)the Strategic Priority Research Program of the Chinese Academy of Sciences (Grant No.XDB33010400)。
文摘Proton transfer(PT) is a process of fundamental importance in hydrogen(H)-bonded systems. At cryogenic or moderate temperatures, pronounced quantum tunneling may happen due to the light mass of H. Single PT processes have been extensively studied. However, for PT involving multiple protons, our understanding remains in its infancy stage due to the complicated interplay between the high-dimensional nature of the process and the quantum nature of tunneling. Cyclic H-bonded systems are typical examples of this, where PT can happen separately via a “stepwise” mechanism or collectively via a “concerted” mechanism. In the first scenario, some protons hop first, typically resulting in metastable intermediate states(ISs) and the reaction pathway passes through multiple transition states. Whilst in the concerted mechanism, all protons move simultaneously, resulting in only one barrier along the path. Here, we review previous experimental and theoretical studies probing quantum tunneling in several representative systems for cyclic PT, with more focus on recent theoretical findings with path-integral based methods. For gas-phase porphyrin and porphycene, as well as porphycene on a metal surface, theoretical predictions are consistent with experimental observations, and enhance our understanding of the processes. Yet, discrepancies in the PT kinetic isotope effects between experiment and theory appear in two systems,most noticeably in water tetramer adsorbed on NaCl(001) surface, and also hinted in porphycene adsorbed on Ag(110)surface. In ice Ih, controversy surrounding concerted PT remains even between experiments. Despite of the recent progress in both theoretical methods and experimental techniques, multiple PT processes in cyclic H-bonded systems remain to be mysterious.
基金supported by the National Natural Science Foundation of China(Nos.82204389 and 82000454)the Medical Science and Technology Research Project of Henan Province(No.SBGJ202103079)the Henan Medical Science and Technology Joint Building Program(Nos.LHGJ20230283,LHGJ20190236,LHGJ20190227,LHGJ20190092,LHGJ20200310,and LHGJ20200284),China.
文摘Cardiovascular diseases(CVDs)are a leading factor driving mortality worldwide.Iron,an essential trace mineral,is important in numerous biological processes,and its role in CVDs has raised broad discussion for decades.Iron-mediated cell death,namely ferroptosis,has attracted much attention due to its critical role in cardiomyocyte damage and CVDs.Furthermore,ferritinophagy is the upstream mechanism that induces ferroptosis,and is closely related to CVDs.This review aims to delineate the processes and mechanisms of ferroptosis and ferritinophagy,and the regulatory pathways and molecular targets involved in ferritinophagy,and to determine their roles in CVDs.Furthermore,we discuss the possibility of targeting ferritinophagy-induced ferroptosis modulators for treating CVDs.Collectively,this review offers some new insights into the pathology of CVDs and identifies possible therapeutic targets.
基金Project supported by the National Key Research and Development Program of China (Grant Nos.2020YFF01014706 and 2017YFC0601901)the National Natural Science Foundation of China (Grant Nos.61571019 and 52177026)。
文摘Josephson junction plays a key role not only in studying the basic physics of unconventional iron-based superconductors but also in realizing practical application of thin-film based devices,therefore the preparation of high-quality iron pnictide Josephson junctions is of great importance.In this work,we have successfully fabricated Josephson junctions from Co-doped BaFe_(2)As_(2)thin films using a direct junction fabrication technique which utilizes high energy focused helium ion beam(FHIB).The electrical transport properties were investigated for junctions fabricated with various He^(+)irradiation doses.The junctions show sharp superconducting transition around 24 K with a narrow transition width of 2.5 K,and a dose correlated foot-structure resistance which corresponds to the effective tuning of junction properties by He^(+)irradiation.Significant J_c suppression by more than two orders of magnitude can be achieved by increasing the He^(+)irradiation dose,which is advantageous for the realization of low noise ion pnictide thin film devices.Clear Shapiro steps are observed under 10 GHz microwave irradiation.The above results demonstrate the successful fabrication of high quality and controllable Co-doped BaFe_(2)As_(2)Josephson junction with high reproducibility using the FHIB technique,laying the foundation for future investigating the mechanism of iron-based superconductors,and also the further implementation in various superconducting electronic devices.
基金supported by the National Key Research and Development Program of China(2016YFB0700901 and 2017YFA0206303)the National Natural Science Foundation of China(51731001,11805006,and 11675006).
文摘Nanoscale permanent magnetic materials,which possess excellent magnetic and mechanical properties,thermal stability,and corrosion resistance,have become a research hotspot for permanent magnets.In reality,however,the obtained maximum energy product,(BH)max,is not satisfactory in comparison with the theory limit,especially for exchange-coupled nanocomposite magnets.The construction of an ideal microstructure still remains a challenge in the synthesis and preparation of nanoscale permanent magnets.This work reported the impact of rapid thermal process(RTP)with electron-beam heating on the microstructures of Nd12.5-xFe80.8+xB6.2Nb0.2Ga0.3(x=0,2.5)nanocomposites.It was found that the crystallization time was greatly reduced,from 15 min under the conventional annealing conditions to 0.1 s under the RTP.For Nd2Fe14B single-phase materials,the crystallization temperature of the RTP ribbons decreased by about 248 C compared with that of the ribbons produced by the conventional annealing method.A synergetic crystallization of the Nd2Fe14B and a-Fe phases was observed under the RTP,which restrained not only the shape,size distribution,and compositions of the hard and the soft phases,but also the interface between them.This modification effect became more obvious as the fraction of Fe increased.Due to the improvement in the uniformity of the Nd2Fe14B and a-Fe phases,and their grain size distribution,better magnetic properties were achieved using RTP in comparison with the conventional annealing method.
基金supported by the State Key Development Program for Basic Research of China (Grant Nos. 2007CB512100 and2006CB601007)the National Natural Science Foundation of China (Grant No. 10674006)+2 种基金the National High Technology Research and Development Program of China (Grant No. 2007AA03Z238)China Postdoctoral Science Foundation (Grant No. 20090461376)the Fundamental Research Funds for the Central Universities (Grant No. KYJD09001)
文摘In this paper, we present a magnetocardiogram (MCG) simulation study using the boundary element method (BEM) and based on the virtual heart model and the realistic human volume conductor model. The different contributions of cardiac equivalent source models and volume conductor models to the MCG are deeply and comprehensively investigated. The single dipole source model, the multiple dipoles source model and the equivalent double layer (EDL) source model are analysed and compared with the cardiac equivalent source models. Meanwhile, the effect of the volume conductor model on the MCG combined with these cardiac equivalent sources is investigated. The simulation results demonstrate that the cardiac electrophysiological information will be partly missed when only the single dipole source is taken, while the EDL source is a good option for MCG simulation and the effect of the volume conductor is smallest for the EDL source. Therefore, the EDL source is suitable for the study of MCG forward and inverse problems, and more attention should be paid to it in future MCG studies.
基金This work was supported by the National Key R&D Program of China(Grant No.2016YFA0301302 and No.2018YFB 2200401)the National Natural Science Foundation of China(Grant Nos.11974058,11825402,11654003,61435001)+4 种基金Beijing Academy of Quantum Information Sciences(Grant No.Y18G20)Key R&D Program of Guangdong Province(Grant No.2018B030329001)Beijing Nova Program(Grant No.Z201100006820125)from Beijing Municipal ScienceTechnology Commission,Fundamental Research Funds for the Central Universities(Grant No.2018XKJC05)the High Performance Computing Platform of Peking University.
文摘Integrated circuit(IC)industry has fully considered the fact that the Moore’s Law is slowing down or ending.Alternative solutions are highly and urgently desired to break the physical size limits in the More-than-Moore era.Integrated silicon photonics technology exhibits distinguished potential to achieve faster operation speed,less power dissipation,and lower cost in IC industry,because their COMS compatibility,fast response,and high monolithic integration capability.Particularly,compared with other on-chip resonators(e.g.microrings,2D photonic crystal cavities)silicon-on-insulator(SOI)-based photonic crystal nanobeam cavity(PCNC)has emerged as a promising platform for on-chip integration,due to their attractive properties of ultra-high Q/V,ultra-compact footprints and convenient integration with silicon bus-waveguides.In this paper,we present a comprehensive review on recent progress of on-chip PCNC devices for lasing,modulation,switching/filting and label-free sensing,etc.
文摘Two groups of coated conductor samples with different thicknesses of CeO2 cap layers deposited by pulsed laser deposition (PLD) under the same conditions have been studied. Of them, one group is of CeO2 films, which are deposited on stainless steel (SS) tapes coated by IBAD-YSZ (IBAD-YSZ/SS), and the other group is of CeO2/YSZ/Y2O3 multilayers, which are deposited on NiW substrates by PLD for the fabrication of YBCO-coated conductor through the RABiTS approach. YBCO film is then deposited on the tops of both types of buffer layers by PLD. The effects of the thickness of the CeO2 film on the texture of the CeO2 film and the critical current density (Jc) of the YBCO film are analysed. For the case of CeO2 film on IBAD-YSZ/SS, there appears a self-epitaxy effect with increasing thickness of the CeO2 film. For CeO2/YSZ/Y2O3/NiW, in which the buffer layers are deposited by PLD, there occurs no self-epitaxy effect, and the optimal thickness of CeO2 is about 50 nm. The surface morphologies of the two groups of samples are examined by SEM.
基金supported by the State Key Development Program for Basic Research of China (Grant No. 2011CBA00106)the National Natural Science Foundation of China (Grant Nos. 10674006, 81171421, and 61101046)the National High Technology Research and Development Program of China (Grant No. 2007AA03Z238)
文摘A cardiac vector model is presented and verified, and then the forward problem for cardiac magnetic fields and electric potential are discussed based on this model and the realistic human torso volume conductor model, including lungs. A torso-cardiac vector model is used for a 12-lead electrocardiographic (ECG) and magneto-cardiogram (MCG) simulation study by using the boundary element method (BEM). Also, we obtain the MCG wave picture using a compound four-channel HTc.SQUID system in a magnetically shielded room. By comparing the simulated results and experimental results, we verify the cardiac vector model and then do a preliminary study of the forward problem of MCG and ECG. Therefore, the results show that the vector model is reasonable in cardiac electrophysiology.
基金supported by the State Key Development Program for Basic Research of China (Grant Nos. 2006CB601007 and 2011CBA00106)the National Natural Science Foundation of China (Grant No. 10674006)the National High Technology Research and Development Program of China (Grant Nos. 2007AA03Z238 and 2007AA03Z213)
文摘In order to eliminate the influence of the large-amplitude magnetic field noise that has complicated magnetocardio- graphic studies since October 2009, we have performed high-accuracy measurement of the environmental magnetic field noise in the vicinity of Beijing Subway Line 4 using a three-component height Tc radio frequency (rf) superconducting quantum interference device (SQUID). By analysing the spatial form and other characteristics of the time and the fre- quency domains and by calculating the circumferential magnetic field distribution based on a duel-end feeding system model, we reach the following conclusions: (i) the main source of magnetic field noise is the magnetic field generated by thel subway trains, and (ii) the magnetic field interference results mainly from the imbalance between traction current and return rail current that is caused by the leakage current.
文摘Since the successful fabrication of two-dimensional (2D) ferromagnetic (FM) monolayer CrI3 and Cr2Ge2Te6, 2D FM materials are becoming an exciting research topic in condensed matter physics and materials fields, as they provide a good platform to explore the fundamental physical properties of magnetic materials under 2D limit. In this review, we summarize the theoretical research progress of intrinsic 2D FM materials and related van der Waals heterostructures (vdWHs) including their electronic structures, magnetism, Curie temperature, valley polarization, and band alignment. Moreover, we also summarize recent researches on the methods that used to regulate the above properties of 2D FM materials and vdWHs, such as defects, doping, strain, electric field and interlayer coupling. These studies show that 2D FM materials have broad application prospects in spintronics and valleytronics. However, there are still many problems waiting to be solved on the way to practical application.