Rapid histology of brain tissues with sufficient diagnostic information has the great potential to aid neurosurgons during operations.Stimulated Raman Scattering(SRS)microscopy is an emerging label-free imaging techni...Rapid histology of brain tissues with sufficient diagnostic information has the great potential to aid neurosurgons during operations.Stimulated Raman Scattering(SRS)microscopy is an emerging label-free imaging technique,with the intrinsic chemical resolutions to delineate brain tumors from normal tissues without the nood of time-consuming tissue processing.Growing number of studies have shown SRS as a“virtual histology"tool for rapid diagnosis of various types of brain tumors.In this review,we focus on the basic principles and current developments of SRS microscopy,as well as its applications for brain tumor imaging.展开更多
基金supports from the National Key Research and Development Program of China (2016YFC0102100,2016YFA0301000,2016YFA0203900)National Natural Science Foundation of China (81671725)+1 种基金Shanghai Rising Star Program (15QA1400500)Shanghai Action Plan for Scientific and Technological Innovation Program (16441909200).
文摘Rapid histology of brain tissues with sufficient diagnostic information has the great potential to aid neurosurgons during operations.Stimulated Raman Scattering(SRS)microscopy is an emerging label-free imaging technique,with the intrinsic chemical resolutions to delineate brain tumors from normal tissues without the nood of time-consuming tissue processing.Growing number of studies have shown SRS as a“virtual histology"tool for rapid diagnosis of various types of brain tumors.In this review,we focus on the basic principles and current developments of SRS microscopy,as well as its applications for brain tumor imaging.
