Summaryof main observation and conclusion A new and intriguing methodology to access various O-difluoromethylation oxime compounds from CICF2H,TBN and indoles is developed under mild reaction conditions.This strategy ...Summaryof main observation and conclusion A new and intriguing methodology to access various O-difluoromethylation oxime compounds from CICF2H,TBN and indoles is developed under mild reaction conditions.This strategy can suppress N-difluoromethylation of indoles successfully,in which there are two different active species(:CF2and·NO)while indoles are unprotected,featuringsimple operation and radical involvement.展开更多
基金Financial support from the National Natural Science Founda-tion of China(No.21772046)the Natural Science Foundation of Fujian Province(No.2016J01064)is gratefully acknowledged.We also thank Instrumental Analysis Center of Huaqiao University for analysis support.X.M.thanks the Subsidized Project for Cul-tivating Postgraduates’Innovative Ability in Scientific Research of Huaqiao University.
文摘Summaryof main observation and conclusion A new and intriguing methodology to access various O-difluoromethylation oxime compounds from CICF2H,TBN and indoles is developed under mild reaction conditions.This strategy can suppress N-difluoromethylation of indoles successfully,in which there are two different active species(:CF2and·NO)while indoles are unprotected,featuringsimple operation and radical involvement.
