BACKGROUND Bell’s palsy is an idiopathic facial palsy with an unknown cause,and 75%of patients heal spontaneously.However,the other 25%of patients continue experiencing mild or severe disabilities,resulting in a redu...BACKGROUND Bell’s palsy is an idiopathic facial palsy with an unknown cause,and 75%of patients heal spontaneously.However,the other 25%of patients continue experiencing mild or severe disabilities,resulting in a reduced quality of life.Currently,various treatment methods have been developed to treat this disease.However,there is controversy regarding their effectiveness,and new alternative treatments are needed.CASE SUMMARY The patient suffered from left-sided facial paralysis due to Bell’s palsy for 7 years.The patient received an uncultured umbilical cord-derived mesenchymal stem cell transplant eight times for treatment.After follow-up for 32 mo,the paralysis was cured,and there was no recurrence.CONCLUSION Uncultured umbilical cord-derived mesenchymal stem cell transplantation may be a potential treatment for patients with Bell’s palsy who do not spontaneously recover.展开更多
BACKGROUND Syringomyelia is a disease caused by the formation of a cavity inside the spinal cord and is accompanied by such symptoms as pain,paresthesia,and urination and defecation disorders,and in severe cases cause...BACKGROUND Syringomyelia is a disease caused by the formation of a cavity inside the spinal cord and is accompanied by such symptoms as pain,paresthesia,and urination and defecation disorders,and in severe cases causes various paralyses.Currently,there are only surgical methods for the treatment of syringomyelia,but these methods carry the possibility of failure,recurrence,and side effects.CASE SUMMARY The patient was a 59-year-old woman who suffered from pain due to syringomyelia.For treatment,the patient received transplant of uncultured umbilical cord-derived mesenchymal stem cells.As intended,the patient's pain was relieved after treatment.Interestingly,an additional benefit was found in that the size of the cavity also decreased.After 2 years from the last treatment,the patient's cavity had almost completely disappeared and her syringomyelia was deemed cured.CONCLUSION Using uncultured umbilical cord-derived mesenchymal stem cells may be a new treatment alternative for syringomyelia.展开更多
文摘BACKGROUND Bell’s palsy is an idiopathic facial palsy with an unknown cause,and 75%of patients heal spontaneously.However,the other 25%of patients continue experiencing mild or severe disabilities,resulting in a reduced quality of life.Currently,various treatment methods have been developed to treat this disease.However,there is controversy regarding their effectiveness,and new alternative treatments are needed.CASE SUMMARY The patient suffered from left-sided facial paralysis due to Bell’s palsy for 7 years.The patient received an uncultured umbilical cord-derived mesenchymal stem cell transplant eight times for treatment.After follow-up for 32 mo,the paralysis was cured,and there was no recurrence.CONCLUSION Uncultured umbilical cord-derived mesenchymal stem cell transplantation may be a potential treatment for patients with Bell’s palsy who do not spontaneously recover.
文摘BACKGROUND Syringomyelia is a disease caused by the formation of a cavity inside the spinal cord and is accompanied by such symptoms as pain,paresthesia,and urination and defecation disorders,and in severe cases causes various paralyses.Currently,there are only surgical methods for the treatment of syringomyelia,but these methods carry the possibility of failure,recurrence,and side effects.CASE SUMMARY The patient was a 59-year-old woman who suffered from pain due to syringomyelia.For treatment,the patient received transplant of uncultured umbilical cord-derived mesenchymal stem cells.As intended,the patient's pain was relieved after treatment.Interestingly,an additional benefit was found in that the size of the cavity also decreased.After 2 years from the last treatment,the patient's cavity had almost completely disappeared and her syringomyelia was deemed cured.CONCLUSION Using uncultured umbilical cord-derived mesenchymal stem cells may be a new treatment alternative for syringomyelia.
