Monitoring the Coasts around Taipei Port with a Marine Radar

Wave field around Taipei Port is studied. Using marine radar as a monitoring device, sequences of the wave field images were obtained on an hourly basis. A 3D-FFT was applied to the image sequences leading to the so-called intensity wavenumber-frequency spectrum. Wave field information can then be extracted from these spectra and compared with on-site measurements. It is shown that, when the prevailing winds are weak, estimated wave heights agree miserably with those measured. On the other hand, when the winds are relatively strong, our estimates follow closely with the trends, but are, in general, lower than measured. Possible reasons leading to these discrepancies are discussed.

Seroprevalence of He/icobacter py/oriin school-aged Chinese in Taipei City and relationship between ABO blood groups

AIM: To explore the seropositive rate of antibodies against H. pylori(anti-HP) in Taipei City and to compare the relationship of ABO blood groups and H. pylori infection.METHODS:In 1993, high school students in Shih-Lin District were randomly selected for blood samplings by their registration number at school. In addition, similar procedures were performed on the well-children clinics of Taipei Veterans General Hospital. Besides, randomly selected sera from the adults who took the physical examination were recruited for evaluation. Informed consents were obtained from all the subjects before blood samplings and parents were simultaneously informed for those who were younger than 18-year-old. Blood tests for anti-HP and ABO blood groupings were performed by enzyme-linked immunosorbent assay.Chi square tests were used for the comparisons between seroprevalence of H. pylori and ABO blood groups.RESULTS: Totally, 685 subjects were recruited (260 children aged 1-14 years, 425 high school students aged 15-18 years)were evaluated, and another 88 adult healthy volunteers were studied as well for comparison. The age-specific seropositive rate of anti-HP was 1.3 % at age 1-5 years,7.7 % at age 6-10 years, and 11.5 % at age 11-14 years.The seroprevalence of H. pylori infection was abruptly increased in young adolescence: 18.6 % at age 15 years,28.1% at age 16 years, 32.4 % at age 17 years and 41.0%at age 18 years, respectively. In the 425 high school students,ABO blood groupings were performed, which disclosed 48.5 % (206/425) of blood group O, 24 % (102/425) of blood group A, 21.8 % (93/425) of blood group B and 5.6 %(24/425) of blood group AB. In comparison of the subjects with blood group O and the other blood groups, no statistical significance could be identified in the seroprevalence of H. pylori(P=0.99).CONCLUSION: The seroprevalence of H. pylori infection in Taipei City in adults is similar to the developed countries,and the abrupt increase of H. pylori during high school may be resulted from marked increase of interpersonal social activities. Although blood group O was reported to be related to H. pylori infection in previous literature, we found no association between H. pylori infection and ABO blood groups.

Using nutritional assessment to predict gender-specific risks of sarcopenia among the elderly receiving health check-up in Taipei

Quality of life for the elderly in an ageing society is receiving more attention than ever. After age 40, muscle mass loses at the rate of 3% to 8% every 10 years. More- over, the decline intensifies after 60 years old. Although many people do not experience changes in total body weight, their muscle mass is slowly replaced by body fat. Decreased muscle mass means lower muscle strength, which affects physical functioning. As a result, daily activities become con- strained, risks of fall and bone fracture elevated,

Service Learning at National Taipei College of Business, 2012-2013＂ New Perspectives on Community, Peer-Based Education

Service learning （also known as peer learning） has received increased attention in tertiary education. By linking learning with authentic volunteer work experience, service learning bridges the gap between theoretical study and practical reality. This practice can increase students＇ professional knowledge, educational development, self-esteem, and awareness of social responsibility. Service learning became a mandatory requirement for all students at National Taipei College of Business （NTCB; now National Taipei University of Business） in 2011, and this is the focus of this study, extending into the 2012 school year. This course-based program allows undergraduate language majors to put their language skills into practice by teaching peers, and also through other volunteer work. This program has greatly benefitted undergraduate students at the school. This study will examine course data, student reports, and interviews with student teachers. The researchers have documented the implementation of the peer-mentor program at NTCB, and the learning gains experienced among students and the professors who assisted in these processes.

Estimation of the Relationship among Fractional Vegetation Cover, Land Surface Temperature and Electricity Consumption in Taipei City

The cooling effects of urban green vegetation cover, which can help decrease LST （land surface temperature） in urban area. When air temperature decreases, the electricity consumption of household will also mitigate loading. Meanwhile, that lack of assessment of green vegetation coverage impact to LST and electricity consumption, so that it could not clearly quantify the environmental contribution of green coves. In Taipei city, for example, FVC （fractional vegetation cover） value and LST was collected from Aster satellite remote sensing images, and data of household electricity consumption was acquired from Taiwan Power Company. Based on these three factors, it analyzed relative model. In the urban area, fractional vegetation cover might influence with land surface temperature and electricity consumption. The result shows that when the value of fractional vegetation cover is low, the air temperature is high. While fractional vegetation cover is increase, not only the land surface temperature is decreasing but the electricity consumption is also reducing. This study hopes can be the reference materials for the future metropolis plan and to inhibit the spread of urban thermal environment.

Language Proficiency, Classroom Attitudes and Linguistic Identity in Taiwan Residents Students： A Report from the National Taipei College of Business

This paper examines Taiwan Residents students＇ attitudes, beliefs, and behaviors in learning English, their language proficiency, cultural factors impacting communicative praxis, and responses toward the use of Chinese and English in daily life. In association with these aims, the author seeks to understand more about how student attitudes, convictions, and performance in foreign language learning and usage are impacted by the culture in which they live and their cultural self-identification. Questions asked in terms of this research include： ＂What are the principal challenges students face in learning English？＂; ＂How do students＇ personalities and cultures of learning transact with these challenges？＂; ＂How do students view their own cultural and linguistic identities in terms of English （and Chinese）？＂; and ＂Overall, what do students need and want from teachers to strengthen their own language skills and learning behaviors？＂. This study began by submitting three questionnaires to students in two ＂Language and Culture＂ classes at National Taipei College of Business in Taipei, Taiwan. There were a total of 76 students, and note that these are not English majors--they are majoring in the Department of Applied Foreign Languages. Although the sample is admittedly small, it is sufficient, and we can reach adequate conclusions about language usage, learning attitudes, and identity expectations in Taiwan Residents students

Public-Private Partnership Model Used in the Taipei Central Station Project Research

In view of the lack of financial aid and the migration of industries,the role of local governments shifted from social reproduction to development and production,which made the development of the local economy their main responsibility.The local governments hence have to face challenges in their management in regards to the arising changes and needs.This Taipei Central Bus Station Build Operate Transfer(BOT)project of urban formation and development is not only a trend in countries around the globe;it is also an area the Taiwan Residents governments are actively involved in.With the impact of urbanization,the size of highly functional cities has surpassed core city administrative regions;therefore,this has generated various planning,administrative and policy issues.This study examines the public-private partnership(PPP)views on urban development;the research methodology will be designed to focus on qualitative research,the following conclusions were made:(1)The basic goal of global city competitiveness of Taipei was promoted by implementing“qlubarnization”,a spatial development strategy dependent on intercalary abilities.(2)Taipei is located in the hub of Asia,linking China's Mainland and Taiwan,facing the world,peaceful and stable,rich and diverse in culture,such that adopting the“hybrid or mixed-use development model”will allow“the national gate of the country program—Central Station,Central Park”to become an international city brand.(3)Taking the“Taipei Main Station PPPs model development of the Taipei Central Bus Station BOT project of nine precincts specific land development projects”as a key success indicator,the government took privatization or PPP into consideration,loosened the monopoly on urban infrastructure,created infrastructure services and a maintenance market,positioned the city as a“supranational”entity in terms of capital flow,and sought a coherent land policy.

利用InSAR形变反演滑坡滑面运动特征——以汶川县布瓦村滑坡为例

当前滑坡滑面运动特征获取多采用接触式手段,费时费力、成本高昂,且仅能获取稀疏点位滑面运动状态。因此,本文提出一种非接触式滑坡滑面运动特征获取方法,其基本思路是:基于位错理论建立滑坡表面形变与滑面运动间的关系模型,同时引入滑面运动平滑约束条件,最终以InSAR等技术获取的地表形变为约束,反演获得滑面运动特征。本文选择四川省汶川县布瓦村滑坡作为研究对象,以时序InSAR技术获取的滑坡坡面升降轨形变数据为约束,基于发展的理论方法反演获得布瓦村滑坡滑面几何与运动学参数,并结合野外勘查、Lidar观测以及模型残差较好地验证了反演结果的可靠性,其中反演升降轨模型残差仅3.1 mm·a^(-1)和3.4 mm·a^(-1)。反演结果显示,布瓦村滑坡滑面位于坡表以下平均~15.0 m深度处,滑面整体以沿坡向运动为主,最大运动量级达~80 mm·a^(-1),同时在坡体西侧中下部发现微量的垂直坡向运动。本文提出方法可方便、快速的获取空间连续的滑坡滑面运动特征,为滑坡灾害预警和失稳风险评估提供更为直接可靠的科学参考。

义必明雅 辞必巧丽——台湾骚体赋论

台湾骚体赋自清代以降一直是重要的文学课题。台湾赋的整理校注工作始自2005年由许俊雅、吴福助主持编纂的《全台赋》。该书承续传统赋作形式,多记台湾形胜地景、自然生态与历史文化。53篇骚体赋应用“兮”字,间有赋中系诗。赋末乱辞亦沿《楚辞》之“歌曰”“辞曰”“和曰”,有简约全篇、收尾之用。《全台赋》作者或为仕台官员或居台文人,其中少数作者具有编纂方志的经验。《全台赋》展现了他们深厚的文化底蕴以及惊采绝艳的视角,涵濡之深可见骚学之递嬗与创新。

移动边缘计算中资源供给不确定下的最优投资和定价问题

为了缓解能源性能的瓶颈,满足更多用户的资源需求,将移动边缘计算(Mobile Edge Computing,MEC)与能量收集(Energy Harvesting,EH)技术相结合,其中,EH技术可以通过捕获环境中的绿色能量来促进设备的可持续计算,提出一个具有随机能量收集的EH-MEC系统,以研究资源供给不确定性的投资和定价问题.用户可以租赁MEC系统的固有资源,也可以使用EH装置收集的资源.由于无线环境的时变性,EH收集的能源具有不确定性,所以,在MEC系统中找到MEC服务器和用户之间的平衡是值得研究的问题.针对这一问题,提出一种序贯决策方法,将用户的投资和MEC服务器资源定价的交互行为建模为一个四阶段的Stackelberg博弈,利用逆向归纳法得到用户与MEC服务器在利润最大化下的纳什均衡解,证明MEC服务器的最优能量收集时间、最优租赁资源和定价决策遵循良好的阈值结构.实验结果表明,绿色资源获取可以显著提高MEC服务器和用户的预期收益.

基于光注入电流调制弱谐振腔法布里珀罗激光器获取光学频率梳

提出了一种基于电流调制弱谐振腔法布里珀罗激光器在外部光注入下产生光学频率梳的方案,实验研究了关键参量对所产生的光学频率梳性能的影响。在该方案中,首先采用频率为1.6 GHz(激光器弛豫振荡频率)、功率为19 dBm的正弦信号直接电流调制弱谐振腔法布里珀罗激光器,使其进入增益开关状态;进一步引入单光注入以及双光注入以获取高性能光学频率梳。实验研究结果表明:采用单光注入时,在合适的注入光功率条件下,连续变化注入光波长可使产生的光学频率梳的中心波长在1525~1560 nm内实现连续调谐。光学频率梳的梳线数目呈现周期性变化,变化周期为激光器的纵模间距0.28 nm(35 GHz);在给定注入光波长条件下,逐渐增加注入光功率,光学频率梳的梳线数目先在一个较高水平附近振荡,然后急剧下降,最后趋于平缓,而光学频率梳的载噪比呈现先增加后饱和的趋势;在优化单光注入参数条件下,获得了梳线功率在10 dB变化范围内包含49根梳线的光学频率梳。引入额外的注入光构建双光注入,在优化的参数条件下,获得了梳线功率在10 dB变化范围内包含92根梳线的光学频率梳。最后,对单光注入和双光注入以及不同注入波长间距的双光注入所产生的光学频率梳各梳齿之间的相干性进行了分析,发现各种光注入方式下所产生的光学频率梳各梳齿之间均具有强的相干性,其拍频信号中基频的单边带相位噪声均处于−125.0 dBc/Hz@10 kHz左右的水平。

Understanding the molecular crossroads in acute liver failure:A pathway to new therapies

In this editorial we comment on the article published in a recent issue of the World Journal of Gastroenterology.Acute liver failure(ALF)is a critical condition characterized by rapid hepatocellular injury and organ dysfunction,and it often necessitates liver transplant to ensure patient survival.Recent research has eluci-dated the involvement of distinct cell death pathways,namely ferroptosis and pyroptosis,in the pathogenesis of ALF.Ferroptosis is driven by iron-dependent lipid peroxidation,whereas pyroptosis is an inflammatory form of cell death;both pathways contribute to hepatocyte death and exacerbate tissue damage.This comprehensive review explores the interplay between ferroptosis and pyroptosis in ALF,highlighting the role of key regulators such as silent information regulator sirtuin 1.Insights from clinical and preclinical studies provide valuable perspectives on the dysregulation of cell death pathways in ALF and the therapeutic potential of targeting these pathways.Collaboration across multiple disciplines is essential for translating the experimental insights into effective treatments for this life-threatening condition.

晚清《启蒙画报》中的“儿童”图像符号学分析

早在晚清第一个新式学制——“癸卯学制”实施之前,当时的知识分子就以办报实践推行教育新观念。西方的一些新教育、新话语和思想经由报刊图文的建构,成为影响近代教育在民间落地与扎根的一环。本研究以中国北方的第一份儿童教育刊物——《启蒙画报》(1902-1904)为分析标的,运用巴特的图像符号学,探究思想转型时期的教育报刊如何运用图像与文字建构儿童形象并传递教育观念。研究从儿童学习知识的三方面——学什么、怎么学、如何用予以呈现,并从“明理/礼”“松绑”“活波”的儿童形象建构中,揭示出文本对儿童主体性的重视及对社会现实的改良关怀,其实用、实际、实现的教育主张扎根于儿童日常生活的经验,体现了比美国教育家杜威更早的实用思想之运用。

Aldo-keto reductase family member C3(AKR1C3)promotes hepatocellular carcinoma cell growth by producing prostaglandin F2α

Hepatocellular carcinoma(HCC)is a leading cause of death worldwide.Current therapies are effective for HCC patients with early disease,but many patients suffer recurrence after surgery and have a poor response to chemotherapy.Therefore,new therapeutic targets are needed.We analyzed gene expression profiles between HCC tissues and normal adjacent tissues from public databases and found that the expression of genes involved in lipid metabolism was significantly different.The analysis showed that AKR1C3 was upregulated in tumors,and high AKR1C3 expression was associated with a poorer prognosis in HCC patients.In vitro,assays demonstrated that the knockdown of AKR1C3 or the addition of the AKR1C3 inhibitor indomethacin suppressed the growth and colony formation of HCC cell lines.Knockdown of AKR1C3 in Huh7 cells reduced tumor growth in vivo.To explore the mechanism,we performed pathway enrichment analysis,and the results linked the expression of AKR1C3 with prostaglandin F2 alpha(PGF2a)downstream target genes.Suppression of AKR1C3 activity reduced the production of PGF2a,and supplementation with PGF2a restored the growth of indomethacin-treated Huh7 cells.Knockdown of the PGF receptor(PTGFR)and treatment with a PTGFR inhibitor significantly reduced HCC growth.We showed that indomethacin potentiated the sensitivity of Huh7 cells to sorafenib.In summary,our results indicate that AKR1C3 upregulation may promote HCC growth by promoting the production of PGF2α,and suppression of PTGFR limited HCC growth.Therefore,targeting the AKR1C3-PGF2a-PTGFR axis may be a new strategy for the treatment of HCC.

“刺客”论析

“刺客”之名,源起于司马迁的《史记·刺客列传》,但自古以来,基于不同理由而进行刺杀行动的事件,层出不穷。“刺客”之进行刺杀行动,往往是受托于人,故有“客”之称,其主结纳的方式,一是“恩义以结之”,二是“财贿以赂之”,司马迁特别强调“恩义”,并将其笔下的刺客与游侠并举,其实乃是同源的;但东汉以后,因“财贿”而刺杀的,逐渐增多,甚至有“会任之家”的专门组织,在历代皆不乏此例。但在晚清之时,新出一种“因政治理念”的不同,而进行刺杀的“刺客”,历来对这种刺客都颇加推崇,实则其中对人性的扭曲、对正义的误解,却是非常危险的。

High glucose reduces Nrf2-dependent cRAGE release and enhances inflammasome-dependent IL-1βproduction in monocytes:the modulatory effects of EGCG

Soluble receptor for advanced glycation end products(sRAGE)acts as a decoy sequestering of RAGE ligands,thus preventing the activation of the ligand-RAGE axis linking human diseases.However,the molecular mechanisms underlying sRAGE remain unclear.In this study,THP-1 monocytes were cultured in normal glucose(NG,5.5 mmol/L)and high glucose(HG,15 mmol/L)to investigate the effects of diabetesrelevant glucose concentrations on sRAGE and interleukin-1β(IL-1β)secretion.The modulatory effects of epigallocatechin gallate(EGCG)in response to HG challenge were also evaluated.HG enhanced intracellular reactive oxygen species(ROS)generation and RAGE expression.The secretion of sRAGE,including esRAGE and cRAGE,was reduced under HG conditions,together with the downregulation of a disintegrin and metallopeptidase 10(ADAM10)and nuclear factor erythroid 2-related factor 2(Nrf2)nuclear translocation.Mechanistically,the HG effects were counteracted by siRAGE and exacerbated by siNrf2.Chromatin immunoprecipitation results showed that Nrf2 binding to the ADAM10 promoter and HG interfered with this binding.Our data reinforce the notion that RAGE and Nrf2 might be sRAGE-regulating factors.Under HG conditions,the treatment of EGCG reduced ROS generation and RAGE activation.EGCG-stimulated cRAGE release was likely caused by the upregulation of the Nrf2-ADAM10 pathway.EGCG inhibited HG-mediated NLRP3 inflammasome activation at least partly by stimulating sRAGE,thereby reducing IL-1βrelease.

我国原创图画书的故事结构特征

图画书的故事结构对儿童语言发展和阅读理解具有重要作用。通过对65本我国原创图画书故事结构特征进行分析,研究发现:我国原创图画书以非人物主角最多,其次是儿童角色;在人称的使用上,以第三人称为主,第一人称其次,没有以第二人称创作的作品;在故事结构类型上,以单一情节和多个情节的数量最多。学龄前适读与小学适读的图画书在主角类型、人称使用以及结构类型的呈现上具有差异性。

宽光束、高均匀性显示贴片灯珠的光学仿真设计

本文通过分析目前显示器用的高均匀宽角度灯珠的光学要求,采用新型非朗伯(non-Lambertian)分布封装Micro-LED芯片,实现了宽光束、高均匀性的微型LED芯片光珠。分析了在不同封装倾角、封装高度、封装材料、封装支架材料、蓝宝石厚度和图案化蓝宝石衬底尺寸下,使用由不同封装材料(铜、钛、铝和银)和材料类型(完全反射和完全吸收)组成的支架模拟固定灯珠的光输出效率和出光角度的变化情况。研究发现通过调整材料、芯片和封装参数,可以得到一个、两个或三个光束,具有贴片灯珠的宽角度、高均匀性的远场光分布特性,满足当前LED和LCD的显示要求。