Objective:To investigate and analyze the current situation of cognition,attitude,behavior,and influencing factors of Type 2 Diabetes Mellitus(T2DM)patients in Neijiang City,and to explore the effectiveness of the appl...Objective:To investigate and analyze the current situation of cognition,attitude,behavior,and influencing factors of Type 2 Diabetes Mellitus(T2DM)patients in Neijiang City,and to explore the effectiveness of the application of the education program based on the popularization of science in general medicine.Methods:Seventy cases of T2DM patients in Neijiang City were selected and randomly divided into 35 cases each in the observation group and the control group.The observation group received general medicine science education intervention and the control group received traditional health education.Indicators such as cognitive level,attitude,and behavioral change between the two groups were compared to assess the effect of general medical science education.Results:Before the intervention,there was no difference between the two groups in terms of knowledge,beliefs,and behaviors in general medicine,glycemic control,body mass index(BMI),and satisfaction with health education(P>0.05).After 3 months of the intervention,there was a highly significant difference in the aforementioned levels between the two groups(P<0.05).Conclusion:The approach of general medicine popularization had a significant effect on the treatment and management of T2DM patients in Neijiang City.It improved the patient’s cognitive level and self-management ability of the disease,increased their treatment adherence,and improved the therapeutic effect.展开更多
Background:Although intensively studied in patients with cardiovascular diseases(CVDs),the prognostic value of diastolic blood pressure(DBP)has little been elucidated in patients with acute exacerbation of chronic obs...Background:Although intensively studied in patients with cardiovascular diseases(CVDs),the prognostic value of diastolic blood pressure(DBP)has little been elucidated in patients with acute exacerbation of chronic obstructive pulmonary disease(AECOPD).This study aimed to reveal the prognostic value of DBP in AECOPD patients.Methods:Inpatients with AECOPD were prospectively enrolled from 10 medical centers in China between September 2017 and July 2021.DBP was measured on admission.The primary outcome was all-cause in-hospital mortality;invasive mechanical ventilation and intensive care unit(ICU)admission were secondary outcomes.Least absolute shrinkage and selection operator(LASSO)and multivariable Cox regressions were used to identify independent prognostic factors and calculate the hazard ratio(HR)and 95%confidence interval(CI)for adverse outcomes.Results:Among 13,633 included patients with AECOPD,197(1.45%)died during their hospital stay.Multivariable Cox regression analysis showed that low DBP on admission(<70 mmHg)was associated with increased risk of in-hospital mortality(HR=2.16,95%CI:1.53–3.05,Z=4.37,P<0.01),invasive mechanical ventilation(HR=1.65,95%CI:1.32–2.05,Z=19.67,P<0.01),and ICU admission(HR=1.45,95%CI:1.24–1.69,Z=22.08,P<0.01)in the overall cohort.Similar findings were observed in subgroups with or without CVDs,except for invasive mechanical ventilation in the subgroup with CVDs.When DBP was further categorized in 5-mmHg increments from<50 mmHg to≥100 mmHg,and 75 to<80 mmHg was taken as reference,HRs for in-hospital mortality increased almost linearly with decreased DBP in the overall cohort and subgroups of patients with CVDs;higher DBP was not associated with the risk of in-hospital mortality.Conclusion:Low on-admission DBP,particularly<70 mmHg,was associated with an increased risk of adverse outcomes among inpatients with AECOPD,with or without CVDs,which may serve as a convenient predictor of poor prognosis in these patients.Clinical Trial Registration:Chinese Clinical Trail Registry,No.ChiCTR2100044625.展开更多
基金Neijiang Science and Technology Program Project/Evaluation of the Effect of Generalization Based on General Medicine in Patients with Type 2 Diabetes Mellitus in Neijiang City(Z202311)。
文摘Objective:To investigate and analyze the current situation of cognition,attitude,behavior,and influencing factors of Type 2 Diabetes Mellitus(T2DM)patients in Neijiang City,and to explore the effectiveness of the application of the education program based on the popularization of science in general medicine.Methods:Seventy cases of T2DM patients in Neijiang City were selected and randomly divided into 35 cases each in the observation group and the control group.The observation group received general medicine science education intervention and the control group received traditional health education.Indicators such as cognitive level,attitude,and behavioral change between the two groups were compared to assess the effect of general medical science education.Results:Before the intervention,there was no difference between the two groups in terms of knowledge,beliefs,and behaviors in general medicine,glycemic control,body mass index(BMI),and satisfaction with health education(P>0.05).After 3 months of the intervention,there was a highly significant difference in the aforementioned levels between the two groups(P<0.05).Conclusion:The approach of general medicine popularization had a significant effect on the treatment and management of T2DM patients in Neijiang City.It improved the patient’s cognitive level and self-management ability of the disease,increased their treatment adherence,and improved the therapeutic effect.
基金National Natural Science Foundation of China(No.82170013)Sichuan Science and Technology Program(No.2022YFS0262)National Key Research Program of China(No.2016YFC1304202)
文摘Background:Although intensively studied in patients with cardiovascular diseases(CVDs),the prognostic value of diastolic blood pressure(DBP)has little been elucidated in patients with acute exacerbation of chronic obstructive pulmonary disease(AECOPD).This study aimed to reveal the prognostic value of DBP in AECOPD patients.Methods:Inpatients with AECOPD were prospectively enrolled from 10 medical centers in China between September 2017 and July 2021.DBP was measured on admission.The primary outcome was all-cause in-hospital mortality;invasive mechanical ventilation and intensive care unit(ICU)admission were secondary outcomes.Least absolute shrinkage and selection operator(LASSO)and multivariable Cox regressions were used to identify independent prognostic factors and calculate the hazard ratio(HR)and 95%confidence interval(CI)for adverse outcomes.Results:Among 13,633 included patients with AECOPD,197(1.45%)died during their hospital stay.Multivariable Cox regression analysis showed that low DBP on admission(<70 mmHg)was associated with increased risk of in-hospital mortality(HR=2.16,95%CI:1.53–3.05,Z=4.37,P<0.01),invasive mechanical ventilation(HR=1.65,95%CI:1.32–2.05,Z=19.67,P<0.01),and ICU admission(HR=1.45,95%CI:1.24–1.69,Z=22.08,P<0.01)in the overall cohort.Similar findings were observed in subgroups with or without CVDs,except for invasive mechanical ventilation in the subgroup with CVDs.When DBP was further categorized in 5-mmHg increments from<50 mmHg to≥100 mmHg,and 75 to<80 mmHg was taken as reference,HRs for in-hospital mortality increased almost linearly with decreased DBP in the overall cohort and subgroups of patients with CVDs;higher DBP was not associated with the risk of in-hospital mortality.Conclusion:Low on-admission DBP,particularly<70 mmHg,was associated with an increased risk of adverse outcomes among inpatients with AECOPD,with or without CVDs,which may serve as a convenient predictor of poor prognosis in these patients.Clinical Trial Registration:Chinese Clinical Trail Registry,No.ChiCTR2100044625.