This paper theoretically studies the free energy and conformational entropy of a long polymer threading a long nanopore （no/N ≥0.1） on external electric field. The polymer expanded model is built in this paper, tha...This paper theoretically studies the free energy and conformational entropy of a long polymer threading a long nanopore （no/N ≥0.1） on external electric field. The polymer expanded model is built in this paper, that is, a single long polymer chain with N monomers （each of size a） threading a pore with no monomers can be regarded as polymer with N ＋ no monomers translocating a 2-dimension hole embedded in membrane. A theoretical approach is presented which explicitly takes into account the nucleation theory. Our calculations imply that, the structure of polymer changes more acutely than other situation, while its leading monomer reaches the second vacuum and its end monomer escapes the first vacuum. And it is also shown that the length scale of polymer and pore play a very important role for polymer translocation dynamics. The present model predicts that the translocation time depends on the chemical potential gradient and the property of the solvent on sides of pore to some extent.展开更多
文摘This paper theoretically studies the free energy and conformational entropy of a long polymer threading a long nanopore （no/N ≥0.1） on external electric field. The polymer expanded model is built in this paper, that is, a single long polymer chain with N monomers （each of size a） threading a pore with no monomers can be regarded as polymer with N ＋ no monomers translocating a 2-dimension hole embedded in membrane. A theoretical approach is presented which explicitly takes into account the nucleation theory. Our calculations imply that, the structure of polymer changes more acutely than other situation, while its leading monomer reaches the second vacuum and its end monomer escapes the first vacuum. And it is also shown that the length scale of polymer and pore play a very important role for polymer translocation dynamics. The present model predicts that the translocation time depends on the chemical potential gradient and the property of the solvent on sides of pore to some extent.
