A Classification–Detection Approach of COVID-19 Based on Chest X-ray and CT by Using Keras Pre-Trained Deep Learning Models

The Coronavirus Disease 2019(COVID-19)is wreaking havoc around the world,bring out that the enormous pressure on national health and medical staff systems.One of the most effective and critical steps in the fight against COVID-19,is to examine the patient’s lungs based on the Chest X-ray and CT generated by radiation imaging.In this paper,five keras-related deep learning models:ResNet50,InceptionResNetV2,Xception,transfer learning and pre-trained VGGNet16 is applied to formulate an classification-detection approaches of COVID-19.Two benchmark methods SVM(Support Vector Machine),CNN(Conventional Neural Networks)are provided to compare with the classification-detection approaches based on the performance indicators,i.e.,precision,recall,F1 scores,confusion matrix,classification accuracy and three types of AUC(Area Under Curve).The highest classification accuracy derived by classification-detection based on 5857 Chest X-rays and 767 Chest CTs are respectively 84%and 75%,which shows that the keras-related deep learning approaches facilitate accurate and effective COVID-19-assisted detection.

A novel preparation of Panax japonicas with high bioequivalence of ginsenoside Rg3

In the present study,we aimed to prepare Panax japonicus tablets and carry out quality inspection.Panax japonicus tablets were prepared by ultrafine pulverization-wet granulation,and quality inspection was carried out according to Pharmacopoeia regulations.The plasma concentration of animals with self-made Panax japonicus tablets or ginsenoside Rg3 in single-dose intragastric administration was determined by high-performance liquid chromatography(HPLC).The pharmacokinetic parameters and relative bioavailability were calculated by DAS 2.0 software.The quality inspection of self-made Panax japonicus tablets met the requirements of Chinese Pharmacopoeia(2015 edition),and this preparation had high bioequivalence of ginsenoside Rg3.The preparation of Panax japonicus tablets was reasonable and highly qualified.Moreover,this new Panax japonicus preparation showed better profiles in oral absorption and utilization.This study provided evidence for the industrial production and clinical application of Panax japonicus tablets.