OBJECTIVE:To explore the prevention of urine retention after subabdominal surgery by electro-acupuncture Yin Ling Quan(SP 9),Zhao Hai(KI 6) acupoints with the assistance of subarachnoid acupoint anesthesia by observin...OBJECTIVE:To explore the prevention of urine retention after subabdominal surgery by electro-acupuncture Yin Ling Quan(SP 9),Zhao Hai(KI 6) acupoints with the assistance of subarachnoid acupoint anesthesia by observing the postoperative voiding time and urine volume of postoperative patients undergoing Electroacupuncture plus subarachnoid block anesthesia.METHODS:60 cases of preoperative expected for subarachnoid block surgery patients were randomly divided into two groups,the treatment group and the control group,with 30 cases in each group.The control group underwent routine subarachnoid anesthesia after surgery without acupuncture treatment group;The treatment group was treated with acupuncture bilateral Yin Ling Quan and Zhaohai acupoints 15 minutes before anesthesia,and then received unilateral electric anesthesia instrument treatment,the intensity of the patient was tolerable(generally 1.5 ~ 2.0 m A),and the routine subarachnoid block anesthesia was performed;The first urination time,urine volume,lower abdominal pain and assistant catheterization were recorded in the two groups.RESULTS:The first postoperative voiding time of the treatment group was significantly earlier compared with that of the control group,there was significant difference(P<0.05);the amount of urine was significantly more than that of the control group in reservation time,there was significant difference(P<0.05);the abdominal pain was light in the treatment group,there was significant difference(P<0.05);the cases of assisted catheterization of the control group were significantly more thanthose of the treatment group,there was significant difference(P< 0.05).CONCLUSION:Electro-acupuncture Yin Ling Quan(SP 9),Zhao Hai(KI 6) acupoints with the assistance of subarachnoid acupoint anesthesia could significantly reduce the urine retention after subabdominal surgery in postoperative patients with ubarachnoid block anesthesiau,accelerate the recovery of bladder function and promote early postoperative urination in addition to relieving the abdominal symptoms after operation.展开更多
Psoriasis is a chronic recurrent inflammatory skin disease, with erythema based on silver-white scales as the main clinical features. The incidence of psoriasis in children has gradually increased, and the clinical ma...Psoriasis is a chronic recurrent inflammatory skin disease, with erythema based on silver-white scales as the main clinical features. The incidence of psoriasis in children has gradually increased, and the clinical manifestations are not typical. Moreover, the drug sensitivity and tolerance of children are different with that of adults. This article reviews the treatment of children's psoriasis in China and abroad.展开更多
Integrase strand transfer inhibitors(INSTIs)have emerged as the first‐line choice for treating human immunodeficiency virus(HIV)infection due to their superior efficacy and safety.However,the impact of INSTIs on the ...Integrase strand transfer inhibitors(INSTIs)have emerged as the first‐line choice for treating human immunodeficiency virus(HIV)infection due to their superior efficacy and safety.However,the impact of INSTIs on the development of neuropsychiatric conditions in people living with HIV(PLWH)is not fully understood due to limited data.In this study,we conducted a cross‐sectional examination of PLWH receiving antiretroviral therapy,with a specific focus on HIV‐positive men who have sex with men(MSM)on INSTI‐based regimens(n=61)and efavirenz(EFV)‐based regimens(n=28).Participants underwent comprehensive neuropsychiatric evaluations and multimodal magnetic resonance imaging(MRI)scans,including T1‐weighted images and resting‐state functional MRI.Compared to the EFV group,the INSTI group exhibited primarily reduced gray matter volume(GMV)in the right superior parietal gyrus,higher regional homogeneity(ReHo)in the left postcentral gyrus,lower ReHo in the right orbital part of the inferior frontal gyrus,and increased voxel‐wise functional connectivity for the seed region in the left inferior temporal gyrus with clusters in the right cuneus.Furthermore,the analysis revealed a main effect of antiretroviral drugs on GMV changes,but no main effect of neuropsychiatric disorders or their interaction.The repeated analysis of participants who did not switch regimens confirmed the GMV changes in the INSTI group,validating the initial findings.Our study demonstrated gray matter atrophy and functional brain changes in PLWH on INSTI‐based regimens compared to those on EFV‐based regimens.These neuroimaging results provide valuable insights into the characteristics of brain network modifications in PLWH receiving INSTI‐based regimens。展开更多
OBJECTIVE: To explore the effect of the Huatan Huoxue Formula combined with atorvastatin calcium in the treatment of coronary heart disease with hyperlipidemia. METHODS: 50 patients with coronary heart disease and hyp...OBJECTIVE: To explore the effect of the Huatan Huoxue Formula combined with atorvastatin calcium in the treatment of coronary heart disease with hyperlipidemia. METHODS: 50 patients with coronary heart disease and hyperlipidemia were randomly divided into the experimental group and the control group, with 25 cases in each group, who were treated in the East Hospital of Beijing University of Chinese Medicine. From March 2015 to April 2016. Patients in the experimental group were given the Huatan Huoxue Formula combined with atorvastatin with 8 weeks; while the control group was just treated with atorvastatin. Blood Lipid changes were compared between the two groups. RESULTS: Blood Lipid levels were significantly improved in the two groups after treatment. Compared with the control group, the levels of TG, TC and LDL-C in the experimental group were decreased, while the HDL-C was increased more significantly. The difference was statistically significant(P<0.05).CONCLUSIONS: The effect of the Huatan Huoxue Formula combined with atorvastatin on coronary heart disease and hyperlipidemia patients is more significant.展开更多
OBJECTIVE:To explore the etiology and pathogenesis of urticaria and its characteristics,advantages of acupuncture and moxibustion treatment of it and the commonly used acupoints,with a prospect of providing clinical g...OBJECTIVE:To explore the etiology and pathogenesis of urticaria and its characteristics,advantages of acupuncture and moxibustion treatment of it and the commonly used acupoints,with a prospect of providing clinical guidance for other doctors.METHODS:Methods and views of urticaria treatment with acupuncture and moxibustion were summarized and the representative acupoints were found out by retrieving related literatures in recent years.RESULTS:Traditional Chinese medicine holds that urticaria is caused by weakness and leads to the wind stroke knot on the skin,which fights against qi and blood and generates wheal..Acupuncture therapy has its unique advantages in treating,which is worth clinical reference and promotion,however,there are still some problems in its clinical study.CONCLUSION:Acupuncture therapy should be combined with reinforcing qi and nourishing blood,detoxification dehumidification,dispelling wind and arresting itching as the principle,as according to the the principle that different symptomsmatch with the corresponding points after selecting the main point.Physiciansshould treat patients by choosing acupuncture point according to the law of syndrome differentiation in selecting,tired to choose acupuncture point,local pick acupuncture point and choosing particular points.As urticaria may attack in any season,in any place and on any person.Therefore,the prevention and treatment of urticariais a protracted war,and needs to strengthen the nursing in the treatmentto achieve the desired effect.展开更多
Ureaplasma Urealyticum(UU) can not only cause a wide range of nongonococcalinfectionsto urogenital tract,but also lead to infertility,sterility,intrauterinefetal infection,abortion or other bad consequences.For males,...Ureaplasma Urealyticum(UU) can not only cause a wide range of nongonococcalinfectionsto urogenital tract,but also lead to infertility,sterility,intrauterinefetal infection,abortion or other bad consequences.For males,UU may cause prostatitis,epididymitis and other diseases.With great harm to the human health,UU infection has been taken as one of the most important STDs in China for prevention and cure.However,the drug resistance of UU is increasingly stronger with the widespread use of antibiotics.Many nongonococcal patients with mycoplasma infection often fail to be cured after a long time of treatment,and drug sensitive tests find that,multidrug resistance brings physical and mental pains to patients all the time.Luckily,integrated Chinese traditional and western medicine greatly improves the cure rate,though the mechanism is not clear.There have been many studies on the reversion action and mechanism of TCM on the antibiotic resistance of bacteria,but studies on the reversion to UU drug resistance are deficient.Here we chose some voluntary patients with multidrug resistance as the research objects,who received treatment in my hospital in recent 3 years.They were given the oral administration of self-prescribed Cangbai Shiduqing Granule.Then,Cangbai Shiduqing Granule's reversion effect on UU drug resistance,namely,the sensitivity transformation situation of drug-resistant antibiotics,was observed.And the observation results are presented in the paper.展开更多
OBJECTIVE: To observe the clinical efficacy of Bushenjiangya(reinforcing kidney and lowering blood pressure) decoction in curing hypertension of kidney Qi deficiency type. METHODS: First 60 patients with hypertension ...OBJECTIVE: To observe the clinical efficacy of Bushenjiangya(reinforcing kidney and lowering blood pressure) decoction in curing hypertension of kidney Qi deficiency type. METHODS: First 60 patients with hypertension of kidney Qi deficiency type were divided into control group and treatment group randomly; the conventional western medicine was given to patients of the control group for antihypertensive therapy, while the traditional Chinese medicine Bushenjiangya decoction was added for patients in the treatment group based on the therapy for those in control group; after 2 months, the blood pressure, clinical efficacy and urine microalbumin changes of patients in the two groups before and after the treatment were observed. RESULTS: a. The systolic pressure of patients in the two groups was all reduced obviously(P<0.05); b. The total effective rate of experiment group in antihypertensive effect was 76.7%, while that of control group was 83.3%(P>0.05); c. The total effective rate of experiment group in TCM syndrome effect was 86.7%, while that of control group was 63.3%, showing that the effect of experiment group was better than that of control group(P<0.05); d. The 24 h urine microalbumin reduction of experiment group was better than that of control group(P<0.05). CONCLUSIONS: The curative effect of Bushenjiangya decoction in combination with the western medicine is better than that of simple western medicine for hypertension of kidney Qi deficiency type, and also the urine microalbumin can be obviously reduced to protect the kidney function.展开更多
Idiopathic pulmonary interstitial fibrosis is one of the respiratory refractory diseases,and the incidence rate is on the rise.At present,the effect of western medicine is not ideal and the side effects are obvious,wh...Idiopathic pulmonary interstitial fibrosis is one of the respiratory refractory diseases,and the incidence rate is on the rise.At present,the effect of western medicine is not ideal and the side effects are obvious,while the traditional Chinese medicine shows good curative effect on the disease.This paper makes a summary on the traditional Chinese medicine theory in treating idiopathic pulmonary interstitial fibrosis in recent years.展开更多
Professor Li has combined TCM and modern medicine in the treatment of skin diseases for more than 30 years and has accumulated rich experience.We summarize some of his clinical experience in treating psoriasis.
OBJECTIVE:To explore the optimal surgery in treating moderate-severe cubital tunnel(CuTS) syndrome by comparing the clinical efficiency of decompression and anterior subcutaneous transposition of ulnar nerve and decom...OBJECTIVE:To explore the optimal surgery in treating moderate-severe cubital tunnel(CuTS) syndrome by comparing the clinical efficiency of decompression and anterior subcutaneous transposition of ulnar nerve and decompression and anterior submuscular transposition of ulnar nerve,and to provide a theoretical basis for the appropriate surgical programs in treating moderate-severe Cu TS.METHODS:47 consecutive cases of moderate-severe Cu TS were surgically treated in our department from January 2014 to January 2017.All patients were divided into two groups by the doctor in our department.21 Cu TS cases were treated with decompression and anterior subcutaneous transposition of ulnar nerve,and other 26 cases were treated with decompression and anterior submuscular transposition of ulnar nerve.All the patients were followed 1 month,3 months and 6 months after operation to evaluate the recovery degree of ulnar nerve function and the clinical efficiency of the two methods was compared.RESULTS:Clinical symptoms of two groups were significant alleviated.There was no significant statistical difference between two groups in the clinical efficiency.CONCLUSION:Completely releasing of nerve truck is the most important step in treating mediate-severe Cu TS.Theclinical results of the two methods are similar,but the anterior subcutaneous transposition of ulnar nerve is more easy to operate and can be widely used.展开更多
Professor Li Yuan-wen is a tutor of doctoral candidates of Beijing university of Chinese medicine. He has combined traditional Chinese and modern medicine in treating skin diseases for more than 30 years in clinical h...Professor Li Yuan-wen is a tutor of doctoral candidates of Beijing university of Chinese medicine. He has combined traditional Chinese and modern medicine in treating skin diseases for more than 30 years in clinical his clinical practice, scientific research and education. He has rich experience in treating all kinds of complex skin diseases and holds a unique opinion. We summarize some of his clinical experience in the treatment of eczema.展开更多
Atopic dermatitis (AD) is a common and frequently encountered disease, which frequently appears in children. According to statistics, the percentage of AD patients between ages of 6 to 20 in dermatology clinics is 3...Atopic dermatitis (AD) is a common and frequently encountered disease, which frequently appears in children. According to statistics, the percentage of AD patients between ages of 6 to 20 in dermatology clinics is 30%^1, and the incidence in school-age children is 2%-3%^2. AD has no corresponding nomenclature in traditional Chinese medicine (TCM). According to the initial time of attack in early childhood, it cma be classified as NaiXuan and TaiXuan; according to the location of the disease (elbow fossa and popliteal fossa), it can be classified as SiWanFeng; according to the specific cases of different characteristics of lesions, it can be classified as ShiChuang, JinYinchuang, XueFengChuang. In TCM, the etiology of AD is complicated. It is generally considered that the pathogenesis of AD is spleen deficiency and damp-heat^3. When children suffer from pathogenic wind, pathogenic dampness, pathogenic heat, or insufficient natural endowment, damp-heat is produced and it injures patients' skin. Also latent damp-heat can deplete the blood and succus in the body, dry the skin and lead to AD. In short, AD can be divided into 3 syndrome types in TCM: syndrome of spleen deficiency, syndrome of damp-heat, syndrome of blood deficiency. At present, the clinical study of AD treated by TCM is increasing, but the study of children's treatment is still rare. This article aims to make a summary of clinical studies of children's AD treated with TCM in recent years.展开更多
Mitophagy is one of the important targets for the prevention and treatment of myocardial ischemia/reperfusion injury(MIRI).Moderate mitophagy can remove damaged mitochondria,inhibit excessive reactive oxygen species a...Mitophagy is one of the important targets for the prevention and treatment of myocardial ischemia/reperfusion injury(MIRI).Moderate mitophagy can remove damaged mitochondria,inhibit excessive reactive oxygen species accumulation,and protect mitochondria from damage.However,excessive enhancement of mitophagy greatly reduces adenosine triphosphate production and energy supply for cell survival,and aggravates cell death.How dysfunctional mitochondria are selectively recognized and engulfed is related to the interaction of adaptors on the mitochondrial membrane,which mainly include phosphatase and tensin homolog deleted on chromosome ten(PTEN)-induced kinase 1/Parkin,hypoxia-inducible factor-1α/Bcl-2 and adenovirus e1b19k Da interacting protein 3,FUN-14 domain containing protein 1 receptor-mediated mitophagy pathway and so on.In this review,the authors briefly summarize the main pathways currently studied on mitophagy and the relationship between mitophagy and MIRI,and incorporate and analyze research data on prevention and treatment of MIRI with Chinese medicine,thereby provide relevant theoretical basis and treatment ideas for clinical prevention of MIRI.展开更多
OBJECTIVE: To compare the clinical effect of brachial plexus block with "One Injection Two Points" guided under ultrasound and the conventional method guiding by ultrasound. METHODS: 70 patients were randomi...OBJECTIVE: To compare the clinical effect of brachial plexus block with "One Injection Two Points" guided under ultrasound and the conventional method guiding by ultrasound. METHODS: 70 patients were randomized evenly into 2 groups, with 35 patients in each group, while the Experiment Group(Group B) received One Injection Two Points" method, the Control Group(Group A) received the conventional method.The nerve block every 5 s, the success rate of anesthesia, the dosage of local anesthetics, second remedial anesthesia, adverse reactions, etc.were recorded. RESULTS: Group B was superior to group A in the success rate of anesthesia; There were 6 patients in group A who required constant pump injection of Remifentanil to remedy, while no patients in Group B needed remedy treatment. There were no serious adverse reactions in both groups.CONCLUSIONS: The clinical effect of brachial plexus block with "One Injection Two Points" method guided under ultrasoundguiding by ultrasound was superior to that of the conventional method.展开更多
文摘OBJECTIVE:To explore the prevention of urine retention after subabdominal surgery by electro-acupuncture Yin Ling Quan(SP 9),Zhao Hai(KI 6) acupoints with the assistance of subarachnoid acupoint anesthesia by observing the postoperative voiding time and urine volume of postoperative patients undergoing Electroacupuncture plus subarachnoid block anesthesia.METHODS:60 cases of preoperative expected for subarachnoid block surgery patients were randomly divided into two groups,the treatment group and the control group,with 30 cases in each group.The control group underwent routine subarachnoid anesthesia after surgery without acupuncture treatment group;The treatment group was treated with acupuncture bilateral Yin Ling Quan and Zhaohai acupoints 15 minutes before anesthesia,and then received unilateral electric anesthesia instrument treatment,the intensity of the patient was tolerable(generally 1.5 ~ 2.0 m A),and the routine subarachnoid block anesthesia was performed;The first urination time,urine volume,lower abdominal pain and assistant catheterization were recorded in the two groups.RESULTS:The first postoperative voiding time of the treatment group was significantly earlier compared with that of the control group,there was significant difference(P<0.05);the amount of urine was significantly more than that of the control group in reservation time,there was significant difference(P<0.05);the abdominal pain was light in the treatment group,there was significant difference(P<0.05);the cases of assisted catheterization of the control group were significantly more thanthose of the treatment group,there was significant difference(P< 0.05).CONCLUSION:Electro-acupuncture Yin Ling Quan(SP 9),Zhao Hai(KI 6) acupoints with the assistance of subarachnoid acupoint anesthesia could significantly reduce the urine retention after subabdominal surgery in postoperative patients with ubarachnoid block anesthesiau,accelerate the recovery of bladder function and promote early postoperative urination in addition to relieving the abdominal symptoms after operation.
基金Open Subject from TCM clinical basic research on psoriasis of the key laboratory of Beijing
文摘Psoriasis is a chronic recurrent inflammatory skin disease, with erythema based on silver-white scales as the main clinical features. The incidence of psoriasis in children has gradually increased, and the clinical manifestations are not typical. Moreover, the drug sensitivity and tolerance of children are different with that of adults. This article reviews the treatment of children's psoriasis in China and abroad.
基金supported by the National Natural Science Foundation of China(82072271,82241072,82072294)the National Key Research and Development Program of China(2021YFC2501402,2021YFC0122601)+8 种基金the Beijing Natural Science Foundation(7222095,7222091)the Peak Talent Program of Beijing Hospital Authority(DFL20191701)the Capital’s Funds for Health Improvement and Research(2022-1-1151)the Research and Translational Application of Clinical Characteristic Diagnostic and Treatment Techniques in Capital City(Z221100007422055)the Beijing Research Center for Respiratory Infectious Diseases(BJRID2024-001)the Beijing Hospitals Authority Innovation Studio of Young Staff Funding Support(2021037)the High-level Public Health Technical Personnel Construction Project(2022-1-007)the High-level Public Health Specialized Talents Project of Beijing Municipal Health commission(2022-02-20)the Beijing Key Laboratory for HIV/AIDS Research(BZ0089).
文摘Integrase strand transfer inhibitors(INSTIs)have emerged as the first‐line choice for treating human immunodeficiency virus(HIV)infection due to their superior efficacy and safety.However,the impact of INSTIs on the development of neuropsychiatric conditions in people living with HIV(PLWH)is not fully understood due to limited data.In this study,we conducted a cross‐sectional examination of PLWH receiving antiretroviral therapy,with a specific focus on HIV‐positive men who have sex with men(MSM)on INSTI‐based regimens(n=61)and efavirenz(EFV)‐based regimens(n=28).Participants underwent comprehensive neuropsychiatric evaluations and multimodal magnetic resonance imaging(MRI)scans,including T1‐weighted images and resting‐state functional MRI.Compared to the EFV group,the INSTI group exhibited primarily reduced gray matter volume(GMV)in the right superior parietal gyrus,higher regional homogeneity(ReHo)in the left postcentral gyrus,lower ReHo in the right orbital part of the inferior frontal gyrus,and increased voxel‐wise functional connectivity for the seed region in the left inferior temporal gyrus with clusters in the right cuneus.Furthermore,the analysis revealed a main effect of antiretroviral drugs on GMV changes,but no main effect of neuropsychiatric disorders or their interaction.The repeated analysis of participants who did not switch regimens confirmed the GMV changes in the INSTI group,validating the initial findings.Our study demonstrated gray matter atrophy and functional brain changes in PLWH on INSTI‐based regimens compared to those on EFV‐based regimens.These neuroimaging results provide valuable insights into the characteristics of brain network modifications in PLWH receiving INSTI‐based regimens。
文摘OBJECTIVE: To explore the effect of the Huatan Huoxue Formula combined with atorvastatin calcium in the treatment of coronary heart disease with hyperlipidemia. METHODS: 50 patients with coronary heart disease and hyperlipidemia were randomly divided into the experimental group and the control group, with 25 cases in each group, who were treated in the East Hospital of Beijing University of Chinese Medicine. From March 2015 to April 2016. Patients in the experimental group were given the Huatan Huoxue Formula combined with atorvastatin with 8 weeks; while the control group was just treated with atorvastatin. Blood Lipid changes were compared between the two groups. RESULTS: Blood Lipid levels were significantly improved in the two groups after treatment. Compared with the control group, the levels of TG, TC and LDL-C in the experimental group were decreased, while the HDL-C was increased more significantly. The difference was statistically significant(P<0.05).CONCLUSIONS: The effect of the Huatan Huoxue Formula combined with atorvastatin on coronary heart disease and hyperlipidemia patients is more significant.
基金Beijing Administration of Traditional Chinese Medicine Development Plan in 13th Five-Year of Key Specialty of DermatologyProject from Human Resources Dept of Dongfang Hospital "Dongfang Famous Doctors"
文摘OBJECTIVE:To explore the etiology and pathogenesis of urticaria and its characteristics,advantages of acupuncture and moxibustion treatment of it and the commonly used acupoints,with a prospect of providing clinical guidance for other doctors.METHODS:Methods and views of urticaria treatment with acupuncture and moxibustion were summarized and the representative acupoints were found out by retrieving related literatures in recent years.RESULTS:Traditional Chinese medicine holds that urticaria is caused by weakness and leads to the wind stroke knot on the skin,which fights against qi and blood and generates wheal..Acupuncture therapy has its unique advantages in treating,which is worth clinical reference and promotion,however,there are still some problems in its clinical study.CONCLUSION:Acupuncture therapy should be combined with reinforcing qi and nourishing blood,detoxification dehumidification,dispelling wind and arresting itching as the principle,as according to the the principle that different symptomsmatch with the corresponding points after selecting the main point.Physiciansshould treat patients by choosing acupuncture point according to the law of syndrome differentiation in selecting,tired to choose acupuncture point,local pick acupuncture point and choosing particular points.As urticaria may attack in any season,in any place and on any person.Therefore,the prevention and treatment of urticariais a protracted war,and needs to strengthen the nursing in the treatmentto achieve the desired effect.
基金National Natural Science Fund(No:81072811)Beijing Administration of Traditional Chinese Medicine Development Plan in 13th Five-Year of Key Specialty of DermatologyProject from Human Resources Dept of Dongfang Hospital "Dongfang Famous Doctors"
文摘Ureaplasma Urealyticum(UU) can not only cause a wide range of nongonococcalinfectionsto urogenital tract,but also lead to infertility,sterility,intrauterinefetal infection,abortion or other bad consequences.For males,UU may cause prostatitis,epididymitis and other diseases.With great harm to the human health,UU infection has been taken as one of the most important STDs in China for prevention and cure.However,the drug resistance of UU is increasingly stronger with the widespread use of antibiotics.Many nongonococcal patients with mycoplasma infection often fail to be cured after a long time of treatment,and drug sensitive tests find that,multidrug resistance brings physical and mental pains to patients all the time.Luckily,integrated Chinese traditional and western medicine greatly improves the cure rate,though the mechanism is not clear.There have been many studies on the reversion action and mechanism of TCM on the antibiotic resistance of bacteria,but studies on the reversion to UU drug resistance are deficient.Here we chose some voluntary patients with multidrug resistance as the research objects,who received treatment in my hospital in recent 3 years.They were given the oral administration of self-prescribed Cangbai Shiduqing Granule.Then,Cangbai Shiduqing Granule's reversion effect on UU drug resistance,namely,the sensitivity transformation situation of drug-resistant antibiotics,was observed.And the observation results are presented in the paper.
文摘OBJECTIVE: To observe the clinical efficacy of Bushenjiangya(reinforcing kidney and lowering blood pressure) decoction in curing hypertension of kidney Qi deficiency type. METHODS: First 60 patients with hypertension of kidney Qi deficiency type were divided into control group and treatment group randomly; the conventional western medicine was given to patients of the control group for antihypertensive therapy, while the traditional Chinese medicine Bushenjiangya decoction was added for patients in the treatment group based on the therapy for those in control group; after 2 months, the blood pressure, clinical efficacy and urine microalbumin changes of patients in the two groups before and after the treatment were observed. RESULTS: a. The systolic pressure of patients in the two groups was all reduced obviously(P<0.05); b. The total effective rate of experiment group in antihypertensive effect was 76.7%, while that of control group was 83.3%(P>0.05); c. The total effective rate of experiment group in TCM syndrome effect was 86.7%, while that of control group was 63.3%, showing that the effect of experiment group was better than that of control group(P<0.05); d. The 24 h urine microalbumin reduction of experiment group was better than that of control group(P<0.05). CONCLUSIONS: The curative effect of Bushenjiangya decoction in combination with the western medicine is better than that of simple western medicine for hypertension of kidney Qi deficiency type, and also the urine microalbumin can be obviously reduced to protect the kidney function.
基金Name:Clinical study of FeiXianTong Decoction improving activity tolerance in patients with idiopathic pulmonary fibrosis.Subject is from Beijing municipal commission of science and technology(number:Z131107002213053)
文摘Idiopathic pulmonary interstitial fibrosis is one of the respiratory refractory diseases,and the incidence rate is on the rise.At present,the effect of western medicine is not ideal and the side effects are obvious,while the traditional Chinese medicine shows good curative effect on the disease.This paper makes a summary on the traditional Chinese medicine theory in treating idiopathic pulmonary interstitial fibrosis in recent years.
基金Open Subject from TCM clinical basic research on Psoriasis of the key laboratory of Beijing"10 kinds of diseases and 10 kinds of medicines"Subject from Beijing municipal commission of science and technology(number:Z131100002513013)Project from Human Resources Dept of Dongfang Hospital"Dongfang Famous Doctors"
文摘Professor Li has combined TCM and modern medicine in the treatment of skin diseases for more than 30 years and has accumulated rich experience.We summarize some of his clinical experience in treating psoriasis.
文摘OBJECTIVE:To explore the optimal surgery in treating moderate-severe cubital tunnel(CuTS) syndrome by comparing the clinical efficiency of decompression and anterior subcutaneous transposition of ulnar nerve and decompression and anterior submuscular transposition of ulnar nerve,and to provide a theoretical basis for the appropriate surgical programs in treating moderate-severe Cu TS.METHODS:47 consecutive cases of moderate-severe Cu TS were surgically treated in our department from January 2014 to January 2017.All patients were divided into two groups by the doctor in our department.21 Cu TS cases were treated with decompression and anterior subcutaneous transposition of ulnar nerve,and other 26 cases were treated with decompression and anterior submuscular transposition of ulnar nerve.All the patients were followed 1 month,3 months and 6 months after operation to evaluate the recovery degree of ulnar nerve function and the clinical efficiency of the two methods was compared.RESULTS:Clinical symptoms of two groups were significant alleviated.There was no significant statistical difference between two groups in the clinical efficiency.CONCLUSION:Completely releasing of nerve truck is the most important step in treating mediate-severe Cu TS.Theclinical results of the two methods are similar,but the anterior subcutaneous transposition of ulnar nerve is more easy to operate and can be widely used.
基金The Beijing municipal commission of science and technology"10 kinds of diseases and 10 kinds of medicines"subject(number:Z131100002513013)The Beijing municipal administration of traditional Chinese medicine"TCM external treatment"project(number:WZF2012-03)Project from Human Resources Dept of Dongfang Hospital"Dongfang Famous Doctors"
文摘Professor Li Yuan-wen is a tutor of doctoral candidates of Beijing university of Chinese medicine. He has combined traditional Chinese and modern medicine in treating skin diseases for more than 30 years in clinical his clinical practice, scientific research and education. He has rich experience in treating all kinds of complex skin diseases and holds a unique opinion. We summarize some of his clinical experience in the treatment of eczema.
文摘Atopic dermatitis (AD) is a common and frequently encountered disease, which frequently appears in children. According to statistics, the percentage of AD patients between ages of 6 to 20 in dermatology clinics is 30%^1, and the incidence in school-age children is 2%-3%^2. AD has no corresponding nomenclature in traditional Chinese medicine (TCM). According to the initial time of attack in early childhood, it cma be classified as NaiXuan and TaiXuan; according to the location of the disease (elbow fossa and popliteal fossa), it can be classified as SiWanFeng; according to the specific cases of different characteristics of lesions, it can be classified as ShiChuang, JinYinchuang, XueFengChuang. In TCM, the etiology of AD is complicated. It is generally considered that the pathogenesis of AD is spleen deficiency and damp-heat^3. When children suffer from pathogenic wind, pathogenic dampness, pathogenic heat, or insufficient natural endowment, damp-heat is produced and it injures patients' skin. Also latent damp-heat can deplete the blood and succus in the body, dry the skin and lead to AD. In short, AD can be divided into 3 syndrome types in TCM: syndrome of spleen deficiency, syndrome of damp-heat, syndrome of blood deficiency. At present, the clinical study of AD treated by TCM is increasing, but the study of children's treatment is still rare. This article aims to make a summary of clinical studies of children's AD treated with TCM in recent years.
基金Supported by the Beijing University of Chinese Medicine Research and Innovation Team Project(No.2019-JYB-TD-08)Youth Science Fund Project of National Natural Science Foundation of China(No.81803906)。
文摘Mitophagy is one of the important targets for the prevention and treatment of myocardial ischemia/reperfusion injury(MIRI).Moderate mitophagy can remove damaged mitochondria,inhibit excessive reactive oxygen species accumulation,and protect mitochondria from damage.However,excessive enhancement of mitophagy greatly reduces adenosine triphosphate production and energy supply for cell survival,and aggravates cell death.How dysfunctional mitochondria are selectively recognized and engulfed is related to the interaction of adaptors on the mitochondrial membrane,which mainly include phosphatase and tensin homolog deleted on chromosome ten(PTEN)-induced kinase 1/Parkin,hypoxia-inducible factor-1α/Bcl-2 and adenovirus e1b19k Da interacting protein 3,FUN-14 domain containing protein 1 receptor-mediated mitophagy pathway and so on.In this review,the authors briefly summarize the main pathways currently studied on mitophagy and the relationship between mitophagy and MIRI,and incorporate and analyze research data on prevention and treatment of MIRI with Chinese medicine,thereby provide relevant theoretical basis and treatment ideas for clinical prevention of MIRI.
文摘OBJECTIVE: To compare the clinical effect of brachial plexus block with "One Injection Two Points" guided under ultrasound and the conventional method guiding by ultrasound. METHODS: 70 patients were randomized evenly into 2 groups, with 35 patients in each group, while the Experiment Group(Group B) received One Injection Two Points" method, the Control Group(Group A) received the conventional method.The nerve block every 5 s, the success rate of anesthesia, the dosage of local anesthetics, second remedial anesthesia, adverse reactions, etc.were recorded. RESULTS: Group B was superior to group A in the success rate of anesthesia; There were 6 patients in group A who required constant pump injection of Remifentanil to remedy, while no patients in Group B needed remedy treatment. There were no serious adverse reactions in both groups.CONCLUSIONS: The clinical effect of brachial plexus block with "One Injection Two Points" method guided under ultrasoundguiding by ultrasound was superior to that of the conventional method.