<strong>Objective:</strong> To investigate the therapeutic effect of Shenmai Injection on postoperative cerebral vasospasm in patients with ruptured aneurysms. <strong>Methods:</strong> Seventy...<strong>Objective:</strong> To investigate the therapeutic effect of Shenmai Injection on postoperative cerebral vasospasm in patients with ruptured aneurysms. <strong>Methods:</strong> Seventy patients undergoing craniotomy for ruptured aneurysms in our hospital were selected as study subjects and randomly divided into control (n = 33) and research (n = 37) groups, they were treated with nimodipine and nimodipine combined with Shenmai injection after operation. The blood flow velocity in the middle cerebral artery (MCA) before and at 1, 3, 7, 11 and 14 days after surgery and the incidence of cerebral vasospasm during these days were compared, and the GCS scores at 14 days postoperatively and GOS scores at 6 months postoperatively were compared between the two groups.<strong> Results:</strong> There were no statistically significant differences in the occurrence of cerebral vasospasm, GCS or GOS scores between the two groups (<em>P</em> > 0.05), but the period of postoperative cerebral vasospasm in the study group was significantly shorter than that in the control group. <strong>Conclusion:</strong> Shenmai injection has the effect of shortening the cycle of occurrence of cerebral vasospasm after the operation of ruptured aneurysms, promoting patients to recover as early as possible and reducing their physical and mental burden.展开更多
The utility model discloses a new type of flat vehicle for emergency patient transfer, comprising a support frame, a bed board, an infusion stand and a transfer assembly;the transfer assembly comprises a trapezoidal b...The utility model discloses a new type of flat vehicle for emergency patient transfer, comprising a support frame, a bed board, an infusion stand and a transfer assembly;the transfer assembly comprises a trapezoidal base fixed on the upper part of the support frame, and a trapezoid mounted on the bottom or side of the bed board. A sliding sleeve, a limit pin, a fixing cylinder and a spring;the trapezoidal sliding sleeve is matched on the trapezoidal base, a pin shaft hole is arranged on the trapezoidal base, the fixing cylinder is fixed on the trapezoidal sliding sleeve, and the limit pin is sleeved in the fixing cylinder, The bottom of the limit pin protrudes from the trapezoidal sliding sleeve, and the upper part is provided with a traction rod;the spring is sleeved on the traction rod, and a limiting plate is arranged at intervals on both sides of the trapezoidal base, and the limiting plate is wrapped in the trapezoidal sliding sleeve. The outer end: by setting the transfer component, the bed board is allowed to be fixed, slid and completely disengaged from the support frame, which is convenient for transferring the bed board together with the patient on it during the patient transfer process. It provides convenience for medical staff.展开更多
Objective： To investigate whether the neural representations underlying alternating two acupoint combinations （ACs） are the same or not. Methods： In this functional magnetic resonance imaging study, two sets of an...Objective： To investigate whether the neural representations underlying alternating two acupoint combinations （ACs） are the same or not. Methods： In this functional magnetic resonance imaging study, two sets of analgesia ACs were utilized, including Waiguan （TE5） and Qiuxu （GB40） for Group A, and Neiguan （PC6） and Taichong （LR3） for Group B, which are the most commonly adopted in clinical treatment. Each group had 20 healthy subjects. An experinlental design was proposed, which consisted of a pre-needling resting phase, a needling phase and a post-needling resting phase. This paradigm optimally mimics the clinical protocol as well as focuses on both the stimulation and the resting periods. The results were subjected to general linear model analysis, conjunction analysis and the functional connectivity analysis. Results： The rostral anterior cingulated cortex was engaged in the initiative period of the acupuncture effect in both groups, and it was chosen as the seed region for the functional connectivity analysis for the following resting period. The results showed that several shared brain regions were involved in both groups, in particular the insula, amygdala and hypothalamus. Moreover, significant differences were located at the posterior cingulated cortex as revealed by a two sample t-test （P〈0.05, corrected）. Other regions showed no significant differences. This finding was further supported by the spatial correlation analysis that the two groups were significantly correlated （r=0.51, P〈0.01）. Conclusion： This preliminary research helps us understand the neurophysiological mechanisms of acupuncture when following clinical guidelines on ACs, as well as provides an important opportunity to develop better treatment strategies for reducing, or even preventing pain.展开更多
文摘<strong>Objective:</strong> To investigate the therapeutic effect of Shenmai Injection on postoperative cerebral vasospasm in patients with ruptured aneurysms. <strong>Methods:</strong> Seventy patients undergoing craniotomy for ruptured aneurysms in our hospital were selected as study subjects and randomly divided into control (n = 33) and research (n = 37) groups, they were treated with nimodipine and nimodipine combined with Shenmai injection after operation. The blood flow velocity in the middle cerebral artery (MCA) before and at 1, 3, 7, 11 and 14 days after surgery and the incidence of cerebral vasospasm during these days were compared, and the GCS scores at 14 days postoperatively and GOS scores at 6 months postoperatively were compared between the two groups.<strong> Results:</strong> There were no statistically significant differences in the occurrence of cerebral vasospasm, GCS or GOS scores between the two groups (<em>P</em> > 0.05), but the period of postoperative cerebral vasospasm in the study group was significantly shorter than that in the control group. <strong>Conclusion:</strong> Shenmai injection has the effect of shortening the cycle of occurrence of cerebral vasospasm after the operation of ruptured aneurysms, promoting patients to recover as early as possible and reducing their physical and mental burden.
文摘The utility model discloses a new type of flat vehicle for emergency patient transfer, comprising a support frame, a bed board, an infusion stand and a transfer assembly;the transfer assembly comprises a trapezoidal base fixed on the upper part of the support frame, and a trapezoid mounted on the bottom or side of the bed board. A sliding sleeve, a limit pin, a fixing cylinder and a spring;the trapezoidal sliding sleeve is matched on the trapezoidal base, a pin shaft hole is arranged on the trapezoidal base, the fixing cylinder is fixed on the trapezoidal sliding sleeve, and the limit pin is sleeved in the fixing cylinder, The bottom of the limit pin protrudes from the trapezoidal sliding sleeve, and the upper part is provided with a traction rod;the spring is sleeved on the traction rod, and a limiting plate is arranged at intervals on both sides of the trapezoidal base, and the limiting plate is wrapped in the trapezoidal sliding sleeve. The outer end: by setting the transfer component, the bed board is allowed to be fixed, slid and completely disengaged from the support frame, which is convenient for transferring the bed board together with the patient on it during the patient transfer process. It provides convenience for medical staff.
基金Supported by the Project for the National Basic Research Program of China(973 Program,No.2012CB518501)the National Natural Science Foundation of China(No.30901900,30930112,and 81101108)+1 种基金the Project of Administration of Traditional Chinese Medicine of Sichuan Province(No.2012-E-038)the Project of Innovative Research Team Research Fund of Sichuan Provincial Education Department(No.12TD002)
文摘Objective： To investigate whether the neural representations underlying alternating two acupoint combinations （ACs） are the same or not. Methods： In this functional magnetic resonance imaging study, two sets of analgesia ACs were utilized, including Waiguan （TE5） and Qiuxu （GB40） for Group A, and Neiguan （PC6） and Taichong （LR3） for Group B, which are the most commonly adopted in clinical treatment. Each group had 20 healthy subjects. An experinlental design was proposed, which consisted of a pre-needling resting phase, a needling phase and a post-needling resting phase. This paradigm optimally mimics the clinical protocol as well as focuses on both the stimulation and the resting periods. The results were subjected to general linear model analysis, conjunction analysis and the functional connectivity analysis. Results： The rostral anterior cingulated cortex was engaged in the initiative period of the acupuncture effect in both groups, and it was chosen as the seed region for the functional connectivity analysis for the following resting period. The results showed that several shared brain regions were involved in both groups, in particular the insula, amygdala and hypothalamus. Moreover, significant differences were located at the posterior cingulated cortex as revealed by a two sample t-test （P〈0.05, corrected）. Other regions showed no significant differences. This finding was further supported by the spatial correlation analysis that the two groups were significantly correlated （r=0.51, P〈0.01）. Conclusion： This preliminary research helps us understand the neurophysiological mechanisms of acupuncture when following clinical guidelines on ACs, as well as provides an important opportunity to develop better treatment strategies for reducing, or even preventing pain.
