Mitigation of urban air pollution has been constrained by the availability of urban spaces for greening.Green walls offer the prospect of greening spaces and surfaces without requiring large areas.Green walls can larg...Mitigation of urban air pollution has been constrained by the availability of urban spaces for greening.Green walls offer the prospect of greening spaces and surfaces without requiring large areas.Green walls can largely be divided into green facades where the aboveground parts of plants rooted in soil and pots grow directly on,and living walls holding bags,planter tiles,trays and vessels containing substrates in which plants are grown.Green facades and living walls can be continuous or modular with repeating units that can be assembled for extension.This review aims to present the effectiveness of green walls in removing different types of air pollutants in indoor and outdoor environments.It examined more than 45 peer-reviewed recently published scholarly articles to achieve the aim.It highlights that most of the studies on green walls focus on particulate matter removal and green walls could effectively remove particulate matter though the effectiveness varies with plant types,air humidity,rainfall and its intensity,leaf area index and contact angle,green wall surface coverage ratio,as well as the height of green walls.Increasing the height of green walls and optimizing their distance from roadsides could promote the deposition of particulate matter.Washing off could regenerate plant surfaces for capturing pollutants.Green walls are also effective in removing NO2,O3,SO2 and CO.Indoor active living walls,when properly designed,could have air purifying performance comparable to a HVAC system.The performance of green walls could be optimized through polycultures,selection of plants,surface coverage and height,and air inflow.展开更多
Background:The mobilization and redistribution of severe acute respiratory syndrome coronavirus 2(SARS-CoV-2)specific T-cells and neutralizing antibodies(nAbs)during exercise is purported to increase immune surveillan...Background:The mobilization and redistribution of severe acute respiratory syndrome coronavirus 2(SARS-CoV-2)specific T-cells and neutralizing antibodies(nAbs)during exercise is purported to increase immune surveillance and protect against severe coronavirus disease 2019(COVID-19).We sought to determine if COVID-19 vaccination would elicit exercise-responsive SARS-CoV-2 T-cells and transiently alter nAb titers.Methods:Eighteen healthy participants completed a 20-min bout of graded cycling exercise before and/or after receiving a COVID-19 vaccine.All major leukocyte subtypes were enumerated before,during,and after exercise by flow cytometry,and immune responses to SARS-CoV-2 were determined using whole blood peptide stimulation assays,T-cell receptor(TCR)-βsequencing,and SARS-CoV-2 nAb serology.Results:COVID-19 vaccination had no effect on the mobilization or egress of major leukocyte subsets in response to intensity-controlled graded exercise.However,non-infected participants had a significantly reduced mobilization of CD4+and CD8+naive T-cells,as well as CD4+central memory T-cells,after vaccination(synthetic immunity group);this was not seen after vaccination in those with prior SARS-CoV-2 infection(hybrid immunity group).Acute exercise after vaccination robustly mobilized SARS-CoV-2 specific T-cells to blood in an intensity-dependent manner.Both groups mobilized T-cells that reacted to spike protein;however,only the hybrid immunity group mobilized T-cells that reacted to membrane and nucleocapsid antigens.nAbs increased significantly during exercise only in the hybrid immunity group.Conclusion:These data indicate that acute exercise mobilizes SARS-CoV-2 specific T-cells that recognize spike protein and increases the redistribution of nAbs in individuals with hybrid immunity.展开更多
BACKGROUND: To evaluate the utilization of point-of-care ultrasound(POCUS) for the assessment of emergency department(ED) patients with musculoskeletal symptoms and the impact of musculoskeletal POCUS on medical decis...BACKGROUND: To evaluate the utilization of point-of-care ultrasound(POCUS) for the assessment of emergency department(ED) patients with musculoskeletal symptoms and the impact of musculoskeletal POCUS on medical decision-making and patient management in the ED.METHODS: This was a retrospective review of ED patients presenting with musculoskeletal symptoms who received a POCUS over a 3.5-year period. An ED POCUS database was reviewed for musculoskeletal POCUS examinations used for medical decision-making. Electronic medical records were then reviewed for demographic characteristics, history, physical examination findings, ED course, additional imaging studies, and impact of musculoskeletal POCUS on patient management in ED. RESULTS: A total of 264 subjects(92 females, 172 males) and 292 musculoskeletal POCUS examinations were included in the fi nal analysis. Most common symptomatic sites were knee(31.8%) and ankle(16.3%). Joint effusion was the most common fi nding on musculoskeletal POCUS, noted in 33.7% of the patients, and subcutaneous edema/cobblestoning was found in 10.2% of the patients. Muscle or tendon rupture was found in 2.3% of the patients, and 1.9% of the patients had joint dislocation. Bursitis or bursa fluid was found in 3.4% of patients, and tendonitis/tendinopathy was found in 2.3%. Twenty percent of them were ultrasound-guided musculoskeletal procedures, and most of them(73.3%) were arthrocentesis. Of the included studies, all except three either changed or helped guide patient management as documented in the patients' medical records.CONCLUSION: Our study fi ndings illustrate the utility of POCUS in the evaluation of a variety of musculoskeletal pathologies in the ED.展开更多
BACKGROUND:Traditionally performed using a subxiphoid approach,the increasing use of point-of-care ultrasound in the emergency department has made other approaches(parasternal and apical)for pericardiocentesis viable....BACKGROUND:Traditionally performed using a subxiphoid approach,the increasing use of point-of-care ultrasound in the emergency department has made other approaches(parasternal and apical)for pericardiocentesis viable.The aim of this study is to identify the ideal approach for emergency-physician-performed ultrasound-guided pericardiocentesis as determined by ultrasound image quality,distance from surface to pericardial fl uid,and likely obstructions or complications.METHODS:A retrospective review of point-of-care cardiac ultrasound examinations was performed in two urban academic emergency departments for the presence of pericardial eff usions.The images were reviewed for technical quality,distance of eff usion from skin surface,and predicted complications.RESULTS:A total of 166 pericardial effusions were identified during the study period.The mean skin-to-pericardial fl uid distance was 5.6 cm(95%confi dence interval[95%CI]5.2-6.0 cm)for the subxiphoid views,which was signifi cantly greater than that for the parasternal(2.7 cm[95%CI 2.5-2.8 cm],P<0.001)and apical(2.5 cm[95%CI 2.3-2.7 cm],P<0.001)views.The subxiphoid view had the highest predicted complication rate at 79.7%(95%CI 71.5%-86.4%),which was signifi cantly greater than the apical(31.9%;95%CI 21.4%-44.0%,P<0.001)and parasternal(20.2%;95%CI 12.8%-29.5%,P<0.001)views.CONCLUSIONS:Our results suggest that complication rates with pericardiocentesis will be lower via the parasternal or apical approach compared to the subxiphoid approach.The distance from skin to fl uid collection is the least in both of these views.展开更多
We review previously published and newly obtained crater size-frequency distributions in the inner solar system. These data indicate that the Moon and the ter- restrial planets have been bombarded by two populations o...We review previously published and newly obtained crater size-frequency distributions in the inner solar system. These data indicate that the Moon and the ter- restrial planets have been bombarded by two populations of objects. Population 1, dominating at early times, had nearly the same size distribution as the present-day asteroid belt, and produced heavily cratered surfaces with a complex, multi-sloped crater size-frequency distribution. Population 2, dominating since about 3.8-3.7 Gyr, had the same size distribution as near-Earth objects (NEOs) and a much lower im- pact flux, and produced a crater size distribution characterized by a differential -3 single-slope power law in the crater diameter range 0.02 km to 100 km. Taken to- gether with the results from a large body of work on age-dating of lunar and meteorite samples and theoretical work in solar system dynamics, a plausible interpretation of these data is as follows. The NEO population is the source of Population 2 and it has been in near-steady state over the past ~ 3.7-3.8 Gyr; these objects are derived from the main asteroid belt by size-dependent non-gravitational effects that favor the ejection of smaller asteroids. However, Population 1 was composed of main belt as- teroids ejected from their source region in a size-independent manner, possibly by means of gravitational resonance sweeping during orbit migration of giant planets; this caused the so-called Late Heavy Bombardment (LHB). The LHB began some time before ~3.9 Gyr, peaked and declined rapidly over the next ~ 100 to 300 Myr, and possibly more slowly from about 3.8-3.7 Gyr to ~2 Gyr. A third crater population (Population S) consisted of secondary impact craters that can dominate the cratering record at small diameters.展开更多
One deficiency of the NCAR Community Land Model (CLM3) is the disappearance of the simulated snow even in the middle of winter over a boreal grassland site due to unrealistically modeled high downward turbulent flux...One deficiency of the NCAR Community Land Model (CLM3) is the disappearance of the simulated snow even in the middle of winter over a boreal grassland site due to unrealistically modeled high downward turbulent fluxes. This is caused by the inappropriate treatment of the vertical snow burial fraction for short vegetation. A new snow burial fraction formulation for short vegetation is then proposed and validated using in situ observations. This modification in the CLM3 largely removes the unrealistic surface turbulent fluxes, leading to a more reasonable snowmelt process, and improves the snow water equivalent (SWE) simulation. Moreover, global offline simulations show that the proposed formulation decreases sensible and latent heat fluxes as well as the ground temperature during the snowmelt season over short vegetation dominant regions. Correspondingly, the SWE is enhanced, leading to the increase in snowmelt-induced runoff during the same period. Furthermore, sensitivity tests indicate that these improvements are insensitive to the exact functional form or parameter values in the proposed formulation.展开更多
The Moon has an anorthositic primordial continental crust. Recently anorthosite has also been discovered on the Martian surface. Although the occurrence of anorthosite is observed to be very limited in Earth's extant...The Moon has an anorthositic primordial continental crust. Recently anorthosite has also been discovered on the Martian surface. Although the occurrence of anorthosite is observed to be very limited in Earth's extant geological record,both lunar and Martian surface geology suggest that anorthosite may have comprised a primordial continent on the early Earth during the first 600 million years after its formation. We hypothesized that differences in the presence of an anorthositic continent on an Earthlike planet are due to planetary size. Earth likely lost its primordial anorthositic continent by tectonic erosion through subduction associated with a kind of proto-plate tectonics(PPT). In contrast, Mars and the Moon, as much smaller planetary bodies, did not lose much of their anorthositic continental crust because mantle convection had weakened and/or largely stopped, and with time, they had appropriately cooled down. Applying this same reasoning to a super-Earth exoplanet suggests that, while a primordial anorthositic continent may briefly form on its surface, such a continent will be likely transported into the deep mantle due to intense mantle convection immediately following its formation. The presence of a primordial continent on an Earth-like planet seems to be essential to whether the planet will be habitable to Earth-like life. The key role of the primordial continent is to provide the necessary and sufficient nutrients for the emergence and evolution of life. With the appearance of a "trinity" consisting of(1) an atmosphere,(2) an ocean, and(3) the primordial continental landmass, material circulation can be maintained to enable a "Habitable Trinity" environment that will permit the emergence of Earth-like life. Thus, with little likelihood of a persistent primordial continent, a super-Earth affords very little chance for Earth-like life to emerge.展开更多
The N-NO2 bond dissociation energies (BDEs) for 7 energetic materials were computed by means of accurate density functional theory (B3LYP, B3PW91 and B3P86) with 6-31G** and 6-311G** basis sets. By comparing t...The N-NO2 bond dissociation energies (BDEs) for 7 energetic materials were computed by means of accurate density functional theory (B3LYP, B3PW91 and B3P86) with 6-31G** and 6-311G** basis sets. By comparing the computed energies and experimental results, we find that the B3P86/6-311G** method can give good results of BDE, which has the mean absolute deviation of 1.30kcal/mol. In addition, substituent effects were also taken into account. It is noted that the Hammett constants of substituent groups are related to the BDEs of the N-NO2 bond and the bond dissociation energies of the energetic materials studied decrease when increasing the number of NO2 group.展开更多
Background: Limonene, a major component in citrus oil, has demonstrated anti-cancer effects in preclinical mammary cancer models. However, the effective oral dose translates to a human dose that may not be feasible fo...Background: Limonene, a major component in citrus oil, has demonstrated anti-cancer effects in preclinical mammary cancer models. However, the effective oral dose translates to a human dose that may not be feasible for chronic dosing. We proposed to evaluate topical application of limonene to the breast as an alternative dosing strategy. Materials and Methods: We conducted a mouse disposition study to determine whether limonene would be bioavailable in the mammary tissue after topical application. SKH-1 mice received topical or oral administration of limonene in the form of orange oil every day for 4 weeks. Plasma and mammary pads were collected 4 hrs after the final dosing. We also conducted an exploratory clinical study to evaluate the safety and feasibility of topically applied limonene in the form of orange oil to the breast. Healthy women were recruited to apply orange oil containing massage oil to their breasts daily for four weeks. Safety and feasibility were assessed by reported adverse events, clinical labs, and usage compliance. Pre and post-intervention nipple aspirate fluid (NAF) and plasma were collected for limonene concentration determination. Results: The mouse disposition study showed that topical and oral orange oil administration resulted in similar mammary tissue disposition of limonene with no clinical signs of toxicity. In the clinical study, the topical application of limonene containing massage oil to the breast was found to be safe with high levels of usage compliance for daily application, although NAF and plasma limonene concentrations were not significantly changed after the massage oil application. Conclusions: Our studies showed that limonene is bioavailable in mammary tissue after topical orange oil application in mice and this novel route of administration to the breast is safe and feasible in healthy women.展开更多
The basement of the Romanian Carpathians is made of Neoproterozoic to early Paleozoic peri- Gondwanan terranes variably involved in the Variscan orogeny, similarly to other basement terrains of Europe. They were hardl...The basement of the Romanian Carpathians is made of Neoproterozoic to early Paleozoic peri- Gondwanan terranes variably involved in the Variscan orogeny, similarly to other basement terrains of Europe. They were hardly dismembered during the Alpine orogeny and traditionally have their own names in the three Carpathian areas. The Danubian domain of the South Carpathians comprises the Dragsan and Lainici-Paiius peri-Amazonian terranes. The Dragsan terrane originated within the ocean surrounding Rodinia and docked with Rodinia at -800 Ma. It does not contain Cadomian magmatism and consequently it is classified as an Avalonian extra-Cadomian terrane, The Lainici-Pfiius terrane is a Ganderian fragment strongly modified by Cadomian subduction-related magmatism, It is attached to the Moesia platform. The TisoviD terrane is an ophiolite that marks the boundary between Drfagsan and Lainici-Paius terranes. The other basement terranes of the Romanian Carpathians originated close to the Ordovician North- African orogen, as a result of the eastern Rheic Ocean opening and closure. Except for the Sebes-Lotru terrane that includes a lower metamorphic unit of Cadomian age, all the other terranes (Bretila, Tulghes, Negrisoara and Rebra in the East Carpathians, Somes, Biharia and Baia de Aries in the Apuseni mountains, Fagaras, Leaota, Carat and Pades in the South Carpathians) represent late Cambrian-Ordovician rock assemblages. Their provenance, is probably within paleo-nortbeast Africa, close to the Arabian-Nubian shield. The late Cambrian-Ordovician terranes are defined here as Carpathian-type terranes. According to their lithostratigraphy and origin, some are of continental margin magmatic arc setting, whereas others formed in rift and back-arc environment and closed to passive continental margin settings. In a paleo- geographic reconstruction, the continental margin magmatic arc terranes were first that drifted out, followed by the passive continental margin terranes with the back-arc terranes in their front. They accreted to Laurussia during the Variscan orogeny. Some of them (Sebes-Lotru in South Carpathians and Baia de Aries in Apuseni mountains) underwent eclogite-grade metamorphism. The Danubian terranes, the Bretila terrane and the Somes terrane were intruded by Variscan granitoids.展开更多
According to Kirillov's idea, the irreducible unitary representations of a Lie group G roughly correspond to the coadjoint orbits (?).In the forward direction one applies the methods of geometric quantization to p...According to Kirillov's idea, the irreducible unitary representations of a Lie group G roughly correspond to the coadjoint orbits (?).In the forward direction one applies the methods of geometric quantization to produce a representation, and in the reverse direction one computes a transform of the character of a representation, to obtain a coadjoint orbit. The method of orbits in the representations of Lie groups suggests the detailed study of coadjoint orbits of a Lie group G in the space (?)~* dual to the Lie algebra (?) of G. In this paper, two primary goals are achieved: one is to completely classify the smooth coadjoint orbits of Virasoro group for nonzero central charge c; the other is to find representatives for coadjoint orbits. These questions have been considered previously by Segal, Kirillov, and Witten, but their results are not quite complete. To accomplish this, the authors start by describing the coadjoint action of D-the Lie group of all orientation preserving diffeomorphisms on the circle S^1, and its central extension (?), then the authors will give a complete classification of smooth coadjoint orbits. In fact, they can be parameterized by a subspace Of conjugacy classes of (?)(1,1). Finally, the authors will show how to find representatives f coadjoint orbits by analyzing the vector fields stabilizing the orbits, and describe the amazing connection between the characteristic (trace) of conjugacy classes of (?)(1, 1) and that of vector fields stabilizing orbits.展开更多
Coronary angiography after cardiac arrest is important to ascertain potential treatable causes of cardiac arrest,salvage myocardium,and potentially increase long-term survival.The cause of adult out-of-hospital cardia...Coronary angiography after cardiac arrest is important to ascertain potential treatable causes of cardiac arrest,salvage myocardium,and potentially increase long-term survival.The cause of adult out-of-hospital cardiac arrest is typically myocardial ischemia.More than 50% of such resuscitated individuals will have an acutely occluded epicardial coronary on emergency coronary angiography.This includes three in four with ST-segment elevation and one in three without STsegment elevation.In the latter the only reliable method of detection is coronary angiography.Numerous cohort studies,now including more than 8000 patients,have shown an association between survival and early coronary angiography and/or percutaneous coronary intervention.Public reporting of percutaneous coronary intervention 30-day mortality rates has been an impediment for extending this therapy to all resuscitated individuals who experienced out-of-hospital cardiac arrest,since current databases to do fully risk-adjust rates for this subgroup.Sincere efforts are under way to correct this situation.展开更多
Conventional streamflow forecasting does not generally take into account the effects of irrigation practice on the magnitude of floods and flash floods. In this paper, we report the results of a study in which we mode...Conventional streamflow forecasting does not generally take into account the effects of irrigation practice on the magnitude of floods and flash floods. In this paper, we report the results of a study in which we modeled the impacts of an irrigated area in the US Southwest on streamflow. A calibrated version of the Variable Infiltration Capacity model (VIC), coupled with a routing algorithm, was used to investigate two strategies for irrigating alfalfa in the Beaver Creek watershed (Arizona, USA), for the period January to March of 2010, at a resolution of 1.8 km and hourly time step. By incorporating the effects of irrigation in artificially maintaining soil moisture, model performance is improved without requiring changes in the resolution or quality of input data. Peak flows in the watershed were found to increase by 10 to 500 times, depending on the irrigation scenario, as a function of the strategy and the intensity of rainfall. The study suggests that both flood control and irrigation efficiency could be enhanced by applying improved irrigation techniques.展开更多
<strong>Purpose:</strong> The purpose of this study is to provide technical information on commissioning the TrueBeam STx 6 MV flattening-filter free (FFF) beam in the RayStation treatment planning system ...<strong>Purpose:</strong> The purpose of this study is to provide technical information on commissioning the TrueBeam STx 6 MV flattening-filter free (FFF) beam in the RayStation treatment planning system (TPS) for stereotactic radiosurgery (SRS) and stereotactic body radiation therapy (SBRT) treatments. <strong>Methods:</strong> For beam modeling, percent depth dose curves, profiles and output factors for jaw-collimated fields and stereotactic cones as well as X-jaws transmission were measured. For multi-leaf collimator (MLC) modeling, MLC model parameters such as offset, gain, curvature, leaf tip width, tongue and groove and transmission were determined and output factors for MLC-collimated fields were measured. Absolute dose calibration was also performed. For beam model and MLC model validation, the American Association of Physicists in Medicine Task Group-119 plans, clinical SRS and SBRT plans and end-to-end testing were performed. <strong>Results:</strong> Beam characteristics of the 6 MV FFF beam agreed well with those in the literature. Validation results showed that our beam model and MLC model were acceptable for SRS and SBRT treatments. <strong>Conclusions:</strong> The technical information and dosimetric data provided in this study will be a useful reference for other clinics/institutions which will commission the same machine energy in the RayStation TPS.展开更多
Gibberellin(GA)functions in plant growth and development.However,genes involved in the biosynthesis and regulation of GA in crop plants are poorly understood.We isolated the mutant gad5-1(GAAssociated Dwarf 5),charact...Gibberellin(GA)functions in plant growth and development.However,genes involved in the biosynthesis and regulation of GA in crop plants are poorly understood.We isolated the mutant gad5-1(GAAssociated Dwarf 5),characterized by dwarfing,short internodes,and dark green and short leaves.Map-based gene cloning and allelic verification confirmed that ZmGAD5 encodes ent-kaurenoic acid oxidase(KAO),which catalyzes KA(ent-kaurenoic acid)to GA12 conversion during GA biosynthesis in maize.ZmGAD5 is localized to the endoplasmic reticulum and is present in multiple maize organs.In gad5-1,the expression of ZmGAD5 is severely reduced,and the levels of the direct substrate of KAO,KA,is increased,leading to a reduction in GA content.The abnormal phenotype of gad5-1 was restored by exogenous application of GA3.The biomass,plant height,and levels of GA12 and GA3 in transgenic Arabidopsis overexpressing ZmGAD5 were increased in comparison with the corresponding controls Col-0.These findings deepen our understanding of genes involved in GA biosynthesis,and could lead to the development of maize lines with improved architecture and higher planting-density tolerance.展开更多
Social determinants of health (SDOH) contribute to cancer disparities among young Latina women (<50 years) residing in the counties along the US-Mexico border. These SDOH are particularly burdensome to young Latina...Social determinants of health (SDOH) contribute to cancer disparities among young Latina women (<50 years) residing in the counties along the US-Mexico border. These SDOH are particularly burdensome to young Latina mothers diagnosed with cancer while they are raising school-age children. Conexiones, a culturally adapted program designed to improve mother and child adjustment to maternal cancer, was piloted with diagnosed Latina mothers residing in border counties in New Mexico and Texas. The purpose of this case analysis was to highlight the SDOH affecting a young Latina mother’s cancer survivorship in the U.S.-Mexico border region. The participant’s Conexiones education sessions were recorded, transcribed, translated to English, back translated to Spanish to establish accuracy, and inductively coded. The participant’s baseline survey indicated she was a young (<50 years), married, Spanish-speaking Latina mother diagnosed with breast cancer while raising a teenage daughter. Seventeen SDOH themes affecting the participant’s cancer experience were identified in the cancer-related emotional triggers she reported across five Conexiones sessions. These themes were organized using Yanez’s conceptual model of determinants of cancer outcomes in Hispanics (i.e., socioeconomic, healthcare, cultural context, and psychosocial). Findings provide direction for cultural adaptations of evidence-based programs.展开更多
In high-altitude cold areas,freeze-thaw(F-T)cycles induced by day-night and seasonal temperature changes cause numerous rock mass slope engineering disasters.To investigate the dynamic properties of rock in the natura...In high-altitude cold areas,freeze-thaw(F-T)cycles induced by day-night and seasonal temperature changes cause numerous rock mass slope engineering disasters.To investigate the dynamic properties of rock in the natural environment of a high-altitude cold area,standard specimens were drilled from the slope of the Jiama copper mine in Tibet,and dynamic compression tests were performed on watersaturated and frozen sandstone with different numbers of F-T cycles(0,10,20,30,and 40)by the split Hopkinson pressure bar(SHPB)system with a cryogenic control system.The influence of water-saturated and frozen conditions on the dynamic performance of sandstone was investigated.The following conclusions are drawn:(1)With increasing strain rate,the attenuation factor(la)of water-saturated sandstone and the intensifying factor(li)of frozen sandstone linearly increase.As the number of F-T cycles increases,the dependence factor(ld)of water-saturated sandstone linearly decreases,whereas the ld of frozen sandstone linearly increases.(2)The prediction equation of the dynamic compressive strength of water-saturated and frozen sandstone is obtained,which can be used to predict the dynamic compressive strength of sandstone after various F-T cycles based on the strain rate.(3)The mesoscopic mechanism of water-saturated and frozen sandstone’s dynamic compressive strength evolution is investigated.The water softening effect causes the dynamic compressive strength of water-saturated sandstone to decrease,whereas the strengthening effect of pore ice causes it to increase.(4)The decrease in the relative dynamic compressive strength of water-saturated sandstone and the increase in the relative dynamic compressive strength of frozen sandstone can be attributed to the increased porosity.展开更多
文摘Mitigation of urban air pollution has been constrained by the availability of urban spaces for greening.Green walls offer the prospect of greening spaces and surfaces without requiring large areas.Green walls can largely be divided into green facades where the aboveground parts of plants rooted in soil and pots grow directly on,and living walls holding bags,planter tiles,trays and vessels containing substrates in which plants are grown.Green facades and living walls can be continuous or modular with repeating units that can be assembled for extension.This review aims to present the effectiveness of green walls in removing different types of air pollutants in indoor and outdoor environments.It examined more than 45 peer-reviewed recently published scholarly articles to achieve the aim.It highlights that most of the studies on green walls focus on particulate matter removal and green walls could effectively remove particulate matter though the effectiveness varies with plant types,air humidity,rainfall and its intensity,leaf area index and contact angle,green wall surface coverage ratio,as well as the height of green walls.Increasing the height of green walls and optimizing their distance from roadsides could promote the deposition of particulate matter.Washing off could regenerate plant surfaces for capturing pollutants.Green walls are also effective in removing NO2,O3,SO2 and CO.Indoor active living walls,when properly designed,could have air purifying performance comparable to a HVAC system.The performance of green walls could be optimized through polycultures,selection of plants,surface coverage and height,and air inflow.
文摘Background:The mobilization and redistribution of severe acute respiratory syndrome coronavirus 2(SARS-CoV-2)specific T-cells and neutralizing antibodies(nAbs)during exercise is purported to increase immune surveillance and protect against severe coronavirus disease 2019(COVID-19).We sought to determine if COVID-19 vaccination would elicit exercise-responsive SARS-CoV-2 T-cells and transiently alter nAb titers.Methods:Eighteen healthy participants completed a 20-min bout of graded cycling exercise before and/or after receiving a COVID-19 vaccine.All major leukocyte subtypes were enumerated before,during,and after exercise by flow cytometry,and immune responses to SARS-CoV-2 were determined using whole blood peptide stimulation assays,T-cell receptor(TCR)-βsequencing,and SARS-CoV-2 nAb serology.Results:COVID-19 vaccination had no effect on the mobilization or egress of major leukocyte subsets in response to intensity-controlled graded exercise.However,non-infected participants had a significantly reduced mobilization of CD4+and CD8+naive T-cells,as well as CD4+central memory T-cells,after vaccination(synthetic immunity group);this was not seen after vaccination in those with prior SARS-CoV-2 infection(hybrid immunity group).Acute exercise after vaccination robustly mobilized SARS-CoV-2 specific T-cells to blood in an intensity-dependent manner.Both groups mobilized T-cells that reacted to spike protein;however,only the hybrid immunity group mobilized T-cells that reacted to membrane and nucleocapsid antigens.nAbs increased significantly during exercise only in the hybrid immunity group.Conclusion:These data indicate that acute exercise mobilizes SARS-CoV-2 specific T-cells that recognize spike protein and increases the redistribution of nAbs in individuals with hybrid immunity.
文摘BACKGROUND: To evaluate the utilization of point-of-care ultrasound(POCUS) for the assessment of emergency department(ED) patients with musculoskeletal symptoms and the impact of musculoskeletal POCUS on medical decision-making and patient management in the ED.METHODS: This was a retrospective review of ED patients presenting with musculoskeletal symptoms who received a POCUS over a 3.5-year period. An ED POCUS database was reviewed for musculoskeletal POCUS examinations used for medical decision-making. Electronic medical records were then reviewed for demographic characteristics, history, physical examination findings, ED course, additional imaging studies, and impact of musculoskeletal POCUS on patient management in ED. RESULTS: A total of 264 subjects(92 females, 172 males) and 292 musculoskeletal POCUS examinations were included in the fi nal analysis. Most common symptomatic sites were knee(31.8%) and ankle(16.3%). Joint effusion was the most common fi nding on musculoskeletal POCUS, noted in 33.7% of the patients, and subcutaneous edema/cobblestoning was found in 10.2% of the patients. Muscle or tendon rupture was found in 2.3% of the patients, and 1.9% of the patients had joint dislocation. Bursitis or bursa fluid was found in 3.4% of patients, and tendonitis/tendinopathy was found in 2.3%. Twenty percent of them were ultrasound-guided musculoskeletal procedures, and most of them(73.3%) were arthrocentesis. Of the included studies, all except three either changed or helped guide patient management as documented in the patients' medical records.CONCLUSION: Our study fi ndings illustrate the utility of POCUS in the evaluation of a variety of musculoskeletal pathologies in the ED.
文摘BACKGROUND:Traditionally performed using a subxiphoid approach,the increasing use of point-of-care ultrasound in the emergency department has made other approaches(parasternal and apical)for pericardiocentesis viable.The aim of this study is to identify the ideal approach for emergency-physician-performed ultrasound-guided pericardiocentesis as determined by ultrasound image quality,distance from surface to pericardial fl uid,and likely obstructions or complications.METHODS:A retrospective review of point-of-care cardiac ultrasound examinations was performed in two urban academic emergency departments for the presence of pericardial eff usions.The images were reviewed for technical quality,distance of eff usion from skin surface,and predicted complications.RESULTS:A total of 166 pericardial effusions were identified during the study period.The mean skin-to-pericardial fl uid distance was 5.6 cm(95%confi dence interval[95%CI]5.2-6.0 cm)for the subxiphoid views,which was signifi cantly greater than that for the parasternal(2.7 cm[95%CI 2.5-2.8 cm],P<0.001)and apical(2.5 cm[95%CI 2.3-2.7 cm],P<0.001)views.The subxiphoid view had the highest predicted complication rate at 79.7%(95%CI 71.5%-86.4%),which was signifi cantly greater than the apical(31.9%;95%CI 21.4%-44.0%,P<0.001)and parasternal(20.2%;95%CI 12.8%-29.5%,P<0.001)views.CONCLUSIONS:Our results suggest that complication rates with pericardiocentesis will be lower via the parasternal or apical approach compared to the subxiphoid approach.The distance from skin to fl uid collection is the least in both of these views.
文摘We review previously published and newly obtained crater size-frequency distributions in the inner solar system. These data indicate that the Moon and the ter- restrial planets have been bombarded by two populations of objects. Population 1, dominating at early times, had nearly the same size distribution as the present-day asteroid belt, and produced heavily cratered surfaces with a complex, multi-sloped crater size-frequency distribution. Population 2, dominating since about 3.8-3.7 Gyr, had the same size distribution as near-Earth objects (NEOs) and a much lower im- pact flux, and produced a crater size distribution characterized by a differential -3 single-slope power law in the crater diameter range 0.02 km to 100 km. Taken to- gether with the results from a large body of work on age-dating of lunar and meteorite samples and theoretical work in solar system dynamics, a plausible interpretation of these data is as follows. The NEO population is the source of Population 2 and it has been in near-steady state over the past ~ 3.7-3.8 Gyr; these objects are derived from the main asteroid belt by size-dependent non-gravitational effects that favor the ejection of smaller asteroids. However, Population 1 was composed of main belt as- teroids ejected from their source region in a size-independent manner, possibly by means of gravitational resonance sweeping during orbit migration of giant planets; this caused the so-called Late Heavy Bombardment (LHB). The LHB began some time before ~3.9 Gyr, peaked and declined rapidly over the next ~ 100 to 300 Myr, and possibly more slowly from about 3.8-3.7 Gyr to ~2 Gyr. A third crater population (Population S) consisted of secondary impact craters that can dominate the cratering record at small diameters.
基金supported by the Key Project of Chinese Academy of Sciences under grant KZCX2-YW-217the National Natural Science Foundation of China (40830103)+1 种基金supported by NSF (ATM0634762)NOAA (NA07NES4400002)
文摘One deficiency of the NCAR Community Land Model (CLM3) is the disappearance of the simulated snow even in the middle of winter over a boreal grassland site due to unrealistically modeled high downward turbulent fluxes. This is caused by the inappropriate treatment of the vertical snow burial fraction for short vegetation. A new snow burial fraction formulation for short vegetation is then proposed and validated using in situ observations. This modification in the CLM3 largely removes the unrealistic surface turbulent fluxes, leading to a more reasonable snowmelt process, and improves the snow water equivalent (SWE) simulation. Moreover, global offline simulations show that the proposed formulation decreases sensible and latent heat fluxes as well as the ground temperature during the snowmelt season over short vegetation dominant regions. Correspondingly, the SWE is enhanced, leading to the increase in snowmelt-induced runoff during the same period. Furthermore, sensitivity tests indicate that these improvements are insensitive to the exact functional form or parameter values in the proposed formulation.
基金supported by JSPS KAKENHI (Grant-in-Aid for Scientific Research on Innovative Areas), Grant Number 26106002(Hadean Bio Science)the Tokyo Dome Corporation for support of the TeNQ exhibitthe branch of Space Exploration Education & Discovery, the University Museum
文摘The Moon has an anorthositic primordial continental crust. Recently anorthosite has also been discovered on the Martian surface. Although the occurrence of anorthosite is observed to be very limited in Earth's extant geological record,both lunar and Martian surface geology suggest that anorthosite may have comprised a primordial continent on the early Earth during the first 600 million years after its formation. We hypothesized that differences in the presence of an anorthositic continent on an Earthlike planet are due to planetary size. Earth likely lost its primordial anorthositic continent by tectonic erosion through subduction associated with a kind of proto-plate tectonics(PPT). In contrast, Mars and the Moon, as much smaller planetary bodies, did not lose much of their anorthositic continental crust because mantle convection had weakened and/or largely stopped, and with time, they had appropriately cooled down. Applying this same reasoning to a super-Earth exoplanet suggests that, while a primordial anorthositic continent may briefly form on its surface, such a continent will be likely transported into the deep mantle due to intense mantle convection immediately following its formation. The presence of a primordial continent on an Earth-like planet seems to be essential to whether the planet will be habitable to Earth-like life. The key role of the primordial continent is to provide the necessary and sufficient nutrients for the emergence and evolution of life. With the appearance of a "trinity" consisting of(1) an atmosphere,(2) an ocean, and(3) the primordial continental landmass, material circulation can be maintained to enable a "Habitable Trinity" environment that will permit the emergence of Earth-like life. Thus, with little likelihood of a persistent primordial continent, a super-Earth affords very little chance for Earth-like life to emerge.
基金The project was supported by the National Natural Science Foundation of China (No. 10774039)
文摘The N-NO2 bond dissociation energies (BDEs) for 7 energetic materials were computed by means of accurate density functional theory (B3LYP, B3PW91 and B3P86) with 6-31G** and 6-311G** basis sets. By comparing the computed energies and experimental results, we find that the B3P86/6-311G** method can give good results of BDE, which has the mean absolute deviation of 1.30kcal/mol. In addition, substituent effects were also taken into account. It is noted that the Hammett constants of substituent groups are related to the BDEs of the N-NO2 bond and the bond dissociation energies of the energetic materials studied decrease when increasing the number of NO2 group.
文摘Background: Limonene, a major component in citrus oil, has demonstrated anti-cancer effects in preclinical mammary cancer models. However, the effective oral dose translates to a human dose that may not be feasible for chronic dosing. We proposed to evaluate topical application of limonene to the breast as an alternative dosing strategy. Materials and Methods: We conducted a mouse disposition study to determine whether limonene would be bioavailable in the mammary tissue after topical application. SKH-1 mice received topical or oral administration of limonene in the form of orange oil every day for 4 weeks. Plasma and mammary pads were collected 4 hrs after the final dosing. We also conducted an exploratory clinical study to evaluate the safety and feasibility of topically applied limonene in the form of orange oil to the breast. Healthy women were recruited to apply orange oil containing massage oil to their breasts daily for four weeks. Safety and feasibility were assessed by reported adverse events, clinical labs, and usage compliance. Pre and post-intervention nipple aspirate fluid (NAF) and plasma were collected for limonene concentration determination. Results: The mouse disposition study showed that topical and oral orange oil administration resulted in similar mammary tissue disposition of limonene with no clinical signs of toxicity. In the clinical study, the topical application of limonene containing massage oil to the breast was found to be safe with high levels of usage compliance for daily application, although NAF and plasma limonene concentrations were not significantly changed after the massage oil application. Conclusions: Our studies showed that limonene is bioavailable in mammary tissue after topical orange oil application in mice and this novel route of administration to the breast is safe and feasible in healthy women.
基金grant IDEI-PN-II-ID-PCE-2011-30100 from the Romanian National Science Foundation(ANCS-CNCS)
文摘The basement of the Romanian Carpathians is made of Neoproterozoic to early Paleozoic peri- Gondwanan terranes variably involved in the Variscan orogeny, similarly to other basement terrains of Europe. They were hardly dismembered during the Alpine orogeny and traditionally have their own names in the three Carpathian areas. The Danubian domain of the South Carpathians comprises the Dragsan and Lainici-Paiius peri-Amazonian terranes. The Dragsan terrane originated within the ocean surrounding Rodinia and docked with Rodinia at -800 Ma. It does not contain Cadomian magmatism and consequently it is classified as an Avalonian extra-Cadomian terrane, The Lainici-Pfiius terrane is a Ganderian fragment strongly modified by Cadomian subduction-related magmatism, It is attached to the Moesia platform. The TisoviD terrane is an ophiolite that marks the boundary between Drfagsan and Lainici-Paius terranes. The other basement terranes of the Romanian Carpathians originated close to the Ordovician North- African orogen, as a result of the eastern Rheic Ocean opening and closure. Except for the Sebes-Lotru terrane that includes a lower metamorphic unit of Cadomian age, all the other terranes (Bretila, Tulghes, Negrisoara and Rebra in the East Carpathians, Somes, Biharia and Baia de Aries in the Apuseni mountains, Fagaras, Leaota, Carat and Pades in the South Carpathians) represent late Cambrian-Ordovician rock assemblages. Their provenance, is probably within paleo-nortbeast Africa, close to the Arabian-Nubian shield. The late Cambrian-Ordovician terranes are defined here as Carpathian-type terranes. According to their lithostratigraphy and origin, some are of continental margin magmatic arc setting, whereas others formed in rift and back-arc environment and closed to passive continental margin settings. In a paleo- geographic reconstruction, the continental margin magmatic arc terranes were first that drifted out, followed by the passive continental margin terranes with the back-arc terranes in their front. They accreted to Laurussia during the Variscan orogeny. Some of them (Sebes-Lotru in South Carpathians and Baia de Aries in Apuseni mountains) underwent eclogite-grade metamorphism. The Danubian terranes, the Bretila terrane and the Somes terrane were intruded by Variscan granitoids.
文摘According to Kirillov's idea, the irreducible unitary representations of a Lie group G roughly correspond to the coadjoint orbits (?).In the forward direction one applies the methods of geometric quantization to produce a representation, and in the reverse direction one computes a transform of the character of a representation, to obtain a coadjoint orbit. The method of orbits in the representations of Lie groups suggests the detailed study of coadjoint orbits of a Lie group G in the space (?)~* dual to the Lie algebra (?) of G. In this paper, two primary goals are achieved: one is to completely classify the smooth coadjoint orbits of Virasoro group for nonzero central charge c; the other is to find representatives for coadjoint orbits. These questions have been considered previously by Segal, Kirillov, and Witten, but their results are not quite complete. To accomplish this, the authors start by describing the coadjoint action of D-the Lie group of all orientation preserving diffeomorphisms on the circle S^1, and its central extension (?), then the authors will give a complete classification of smooth coadjoint orbits. In fact, they can be parameterized by a subspace Of conjugacy classes of (?)(1,1). Finally, the authors will show how to find representatives f coadjoint orbits by analyzing the vector fields stabilizing the orbits, and describe the amazing connection between the characteristic (trace) of conjugacy classes of (?)(1, 1) and that of vector fields stabilizing orbits.
文摘Coronary angiography after cardiac arrest is important to ascertain potential treatable causes of cardiac arrest,salvage myocardium,and potentially increase long-term survival.The cause of adult out-of-hospital cardiac arrest is typically myocardial ischemia.More than 50% of such resuscitated individuals will have an acutely occluded epicardial coronary on emergency coronary angiography.This includes three in four with ST-segment elevation and one in three without STsegment elevation.In the latter the only reliable method of detection is coronary angiography.Numerous cohort studies,now including more than 8000 patients,have shown an association between survival and early coronary angiography and/or percutaneous coronary intervention.Public reporting of percutaneous coronary intervention 30-day mortality rates has been an impediment for extending this therapy to all resuscitated individuals who experienced out-of-hospital cardiac arrest,since current databases to do fully risk-adjust rates for this subgroup.Sincere efforts are under way to correct this situation.
文摘Conventional streamflow forecasting does not generally take into account the effects of irrigation practice on the magnitude of floods and flash floods. In this paper, we report the results of a study in which we modeled the impacts of an irrigated area in the US Southwest on streamflow. A calibrated version of the Variable Infiltration Capacity model (VIC), coupled with a routing algorithm, was used to investigate two strategies for irrigating alfalfa in the Beaver Creek watershed (Arizona, USA), for the period January to March of 2010, at a resolution of 1.8 km and hourly time step. By incorporating the effects of irrigation in artificially maintaining soil moisture, model performance is improved without requiring changes in the resolution or quality of input data. Peak flows in the watershed were found to increase by 10 to 500 times, depending on the irrigation scenario, as a function of the strategy and the intensity of rainfall. The study suggests that both flood control and irrigation efficiency could be enhanced by applying improved irrigation techniques.
文摘<strong>Purpose:</strong> The purpose of this study is to provide technical information on commissioning the TrueBeam STx 6 MV flattening-filter free (FFF) beam in the RayStation treatment planning system (TPS) for stereotactic radiosurgery (SRS) and stereotactic body radiation therapy (SBRT) treatments. <strong>Methods:</strong> For beam modeling, percent depth dose curves, profiles and output factors for jaw-collimated fields and stereotactic cones as well as X-jaws transmission were measured. For multi-leaf collimator (MLC) modeling, MLC model parameters such as offset, gain, curvature, leaf tip width, tongue and groove and transmission were determined and output factors for MLC-collimated fields were measured. Absolute dose calibration was also performed. For beam model and MLC model validation, the American Association of Physicists in Medicine Task Group-119 plans, clinical SRS and SBRT plans and end-to-end testing were performed. <strong>Results:</strong> Beam characteristics of the 6 MV FFF beam agreed well with those in the literature. Validation results showed that our beam model and MLC model were acceptable for SRS and SBRT treatments. <strong>Conclusions:</strong> The technical information and dosimetric data provided in this study will be a useful reference for other clinics/institutions which will commission the same machine energy in the RayStation TPS.
基金the National Natural Science Foundation of China(U21A20206,Chun-Peng Song)the Project of Sanya Yazhou Bay Science and Technology City(SCKJJYRC-2022-78,Baozhu Li)+1 种基金the Program for Innovative Research Team(in Science and Technology)in University of Henan Province(21IRTSTHN019,Siyi Guo)the 111 Project of China(D16014).
文摘Gibberellin(GA)functions in plant growth and development.However,genes involved in the biosynthesis and regulation of GA in crop plants are poorly understood.We isolated the mutant gad5-1(GAAssociated Dwarf 5),characterized by dwarfing,short internodes,and dark green and short leaves.Map-based gene cloning and allelic verification confirmed that ZmGAD5 encodes ent-kaurenoic acid oxidase(KAO),which catalyzes KA(ent-kaurenoic acid)to GA12 conversion during GA biosynthesis in maize.ZmGAD5 is localized to the endoplasmic reticulum and is present in multiple maize organs.In gad5-1,the expression of ZmGAD5 is severely reduced,and the levels of the direct substrate of KAO,KA,is increased,leading to a reduction in GA content.The abnormal phenotype of gad5-1 was restored by exogenous application of GA3.The biomass,plant height,and levels of GA12 and GA3 in transgenic Arabidopsis overexpressing ZmGAD5 were increased in comparison with the corresponding controls Col-0.These findings deepen our understanding of genes involved in GA biosynthesis,and could lead to the development of maize lines with improved architecture and higher planting-density tolerance.
文摘Social determinants of health (SDOH) contribute to cancer disparities among young Latina women (<50 years) residing in the counties along the US-Mexico border. These SDOH are particularly burdensome to young Latina mothers diagnosed with cancer while they are raising school-age children. Conexiones, a culturally adapted program designed to improve mother and child adjustment to maternal cancer, was piloted with diagnosed Latina mothers residing in border counties in New Mexico and Texas. The purpose of this case analysis was to highlight the SDOH affecting a young Latina mother’s cancer survivorship in the U.S.-Mexico border region. The participant’s Conexiones education sessions were recorded, transcribed, translated to English, back translated to Spanish to establish accuracy, and inductively coded. The participant’s baseline survey indicated she was a young (<50 years), married, Spanish-speaking Latina mother diagnosed with breast cancer while raising a teenage daughter. Seventeen SDOH themes affecting the participant’s cancer experience were identified in the cancer-related emotional triggers she reported across five Conexiones sessions. These themes were organized using Yanez’s conceptual model of determinants of cancer outcomes in Hispanics (i.e., socioeconomic, healthcare, cultural context, and psychosocial). Findings provide direction for cultural adaptations of evidence-based programs.
基金supported by the Hunan Provincial Natural Science Foundation of China(Grant No.2020JJ4704)the Fundamental Research Funds for the Central Universities of Central South University,China(Grant Nos.2021zzts0881 and 2021zzts0279).
文摘In high-altitude cold areas,freeze-thaw(F-T)cycles induced by day-night and seasonal temperature changes cause numerous rock mass slope engineering disasters.To investigate the dynamic properties of rock in the natural environment of a high-altitude cold area,standard specimens were drilled from the slope of the Jiama copper mine in Tibet,and dynamic compression tests were performed on watersaturated and frozen sandstone with different numbers of F-T cycles(0,10,20,30,and 40)by the split Hopkinson pressure bar(SHPB)system with a cryogenic control system.The influence of water-saturated and frozen conditions on the dynamic performance of sandstone was investigated.The following conclusions are drawn:(1)With increasing strain rate,the attenuation factor(la)of water-saturated sandstone and the intensifying factor(li)of frozen sandstone linearly increase.As the number of F-T cycles increases,the dependence factor(ld)of water-saturated sandstone linearly decreases,whereas the ld of frozen sandstone linearly increases.(2)The prediction equation of the dynamic compressive strength of water-saturated and frozen sandstone is obtained,which can be used to predict the dynamic compressive strength of sandstone after various F-T cycles based on the strain rate.(3)The mesoscopic mechanism of water-saturated and frozen sandstone’s dynamic compressive strength evolution is investigated.The water softening effect causes the dynamic compressive strength of water-saturated sandstone to decrease,whereas the strengthening effect of pore ice causes it to increase.(4)The decrease in the relative dynamic compressive strength of water-saturated sandstone and the increase in the relative dynamic compressive strength of frozen sandstone can be attributed to the increased porosity.