Objective To clarify the clinical efficacy of first-line oral antiviral drugs tenofovir alafenamide(TAF),tenofovir disoproxil fumarate(TDF),and entecavir(ETV)in the treatment of chronic hepatitis B(CHB)and their safet...Objective To clarify the clinical efficacy of first-line oral antiviral drugs tenofovir alafenamide(TAF),tenofovir disoproxil fumarate(TDF),and entecavir(ETV)in the treatment of chronic hepatitis B(CHB)and their safety profiles with lipid,bone,and kidney metabolism.Methods 458 CHB cases diagnosed and treated at the Department of Hepatology of Integrated Traditional Chinese and Western Medicine of the Third Hospital of Hebei Medical University from February 2010to November 2022 were selected.展开更多
文摘Objective To clarify the clinical efficacy of first-line oral antiviral drugs tenofovir alafenamide(TAF),tenofovir disoproxil fumarate(TDF),and entecavir(ETV)in the treatment of chronic hepatitis B(CHB)and their safety profiles with lipid,bone,and kidney metabolism.Methods 458 CHB cases diagnosed and treated at the Department of Hepatology of Integrated Traditional Chinese and Western Medicine of the Third Hospital of Hebei Medical University from February 2010to November 2022 were selected.