Objective: To preliminarily explore the relationship between thrombosis and its associated factors in patients with coronary heart disease (CHD) of turbidity-phlegm blocking syndrome (TPB), and to study its actin...Objective: To preliminarily explore the relationship between thrombosis and its associated factors in patients with coronary heart disease (CHD) of turbidity-phlegm blocking syndrome (TPB), and to study its acting mechanism. Methods: Plasma levels of thrombosis-associated factors, including Von Willebrand factor (vWF), D-dimer, and fibrinogen (Fg), in 85 patients of CHD with TPB, 93 with CHD of non-TPD, and 89 healthy persons were detected and compared. Results: Levels of the three factors were increased in all the CHD patients, and were higher in TPB patients than in non-TPB patients (P〈0.01 or P〈0.05). Conclusion: The TPB syndrome in CHD patients was closely related to the blood coagulation-fibrinolytic system; they might be in prethrombosis state, and the plasma levels of vWF, D-dimer, and Fg could be taken as the objective indices for differentiation of TPB syndrome in CHD patients.展开更多
文摘Objective: To preliminarily explore the relationship between thrombosis and its associated factors in patients with coronary heart disease (CHD) of turbidity-phlegm blocking syndrome (TPB), and to study its acting mechanism. Methods: Plasma levels of thrombosis-associated factors, including Von Willebrand factor (vWF), D-dimer, and fibrinogen (Fg), in 85 patients of CHD with TPB, 93 with CHD of non-TPD, and 89 healthy persons were detected and compared. Results: Levels of the three factors were increased in all the CHD patients, and were higher in TPB patients than in non-TPB patients (P〈0.01 or P〈0.05). Conclusion: The TPB syndrome in CHD patients was closely related to the blood coagulation-fibrinolytic system; they might be in prethrombosis state, and the plasma levels of vWF, D-dimer, and Fg could be taken as the objective indices for differentiation of TPB syndrome in CHD patients.